Results 101 to 110 of about 2,323,053 (317)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
What Determines Employment of Part-Time Faculty in Higher Education Institutions? [PDF]
, 2007 This study uses a cross-section national sample of four-year colleges and universities in the United States to examine the variation of part-time faculty employment.
Liu, Xiangmin, Zhang, Liang
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Advanced Photonics ResearchCarbon dots (CDs) show great application potential with their unique and excellent performances. Coal and its derivatives are rich in aromatic ring structure, which is suitable for preparing CDs in microstructure.
Zhexian Zhao +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Changes in the Academic Labor Market for Economists [PDF]
, 2004 [Excerpt] American colleges and universities are increasingly substituting non-tenure track full-time and part-time faculty for full-time tenured and tenure track faculty.
Ehrenberg, Ronald G
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Nature CommunicationsActivatable afterglow luminescence nanoprobes enabling switched “off-on” signals in response to biomarkers have recently emerged to achieve reduced unspecific signals and improved imaging fidelity.
Yue Jiang +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Higher education means business: a summary of the economic impact of Scottish higher educaton institutions [PDF]
, 2006 This study examined key economic features of the Scottish higher education institutions (HEIs) in the academic and financial year 2004 -2005 together with those aspects of their contribution to the economy that can be readily measured.
Donald, Kelly +2 more
core