Results 51 to 60 of about 2,323,053 (317)

Corruption risks in higher education institution

Journal of actual problems of jurisprudence, 2021
The article examines some corruption risks that exist in the field of higher education in Kazakhstan. Currently, the identification of corruption risks in the activities of higher education institutions is one of the most effective mechanisms to prevent the occurrence of corruption in the field of education.
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DFT Study on the Possible Intramolecular Rearrangement of Four Monocyclic Monoterpenes [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2018
As the basis and preliminary work of future experimental study on PAHs formation under high temperature, theoretical computations on the intramolecular rearrangement reactions of sylvestrene (1-methyl-3-vinylcyclohexene) and 1,4-dimethyl-4 ...
Li He, Wang Dong, Wang Chuanming
doaj  

Rare earth separations by selective borate crystallization

Nature Communications, 2017
Trivalent lanthanides possess similar chemical properties, making their separation from one another challenging. Here, Wang and colleagues demonstrate that their subtle chemical differences can be greatly amplified during borate crystallization, leading ...
Xuemiao Yin, Yaxing Wang, Xiaojing Bai, Yumin Wang, Lanhua Chen, Chengliang Xiao, Juan Diwu, Shiyu Du, Zhifang Chai, Thomas E. Albrecht-Schmitt, Shuao Wang   +10 more
doaj   +1 more source

Financing Higher Education Institutions in the 21st Century [PDF]

, 2003
[Excerpt] My remarks today relate to the “Financing of American Higher Education Institutions in the 21st Century”. Although the discussion has some implications for the ability of students and their families to finance college educations, my focus is on
Ehrenberg, Ronald G
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of soil quality and analysis of drivers of different vegetation patterns in the loess region of Northern Shaanxi

Scientific Reports
Evaluating the effects of different vegetation patterns on soil quality and clarifying the soil quality drivers in the loess area of northern Shaanxi are highly important for the future land use and vegetation optimization in this area.
Youfu Wang, Fangfang Qiang, Guangquan Liu, Changhai Liu, Jie Gao, Ning Ai   +5 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source