Results 61 to 70 of about 297,937 (262)
An Improved Approximate-Bayesian Model-choice Method for Estimating Shared Evolutionary History [PDF]
, 2014 To understand biological diversification, it is important to account for large-scale processes that affect the evolutionary history of groups of co-distributed populations of organisms.
Oaks, Jamie R.
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
NeuroImage: Clinical, 2019 The “sensory processing disorder” (SPD) refers to brain's inability to organize sensory input for appropriate use. In this study, we determined the diffusion tensor imaging (DTI) microstructural and connectivity correlates of SPD, and apply machine ...
Seyedmehdi Payabvash +8 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
On predictive probability matching priors
, 2008 We revisit the question of priors that achieve approximate matching of Bayesian and frequentist predictive probabilities. Such priors may be thought of as providing frequentist calibration of Bayesian prediction or simply as devices for producing ...
Sweeting, Trevor J.
core +1 more source
Estimation of Inverse Weibull Distribution Under Type-I Hybrid Censoring [PDF]
, 2020 The hybrid censoring is a mixture of Type I and Type II censoring schemes. This paper presents the statistical inferences of the Inverse Weibull distribution when the data are Type-I hybrid censored. First we consider the maximum likelihood estimators of
Azizpour, Mina, Kazemi, Mohammad
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Science and Technology of Advanced Materials: MethodsX-ray magnetic circular dichroism (MCD) spectra are the difference spectra of X-ray absorption (XA) measured in magnetic materials with left and right circular polarizations ([Formula: see text]helicity) under a magnetic field.
Taiga Yamasaki +7 more
doaj +1 more source
Trends in Computational and Applied Mathematics, 2006 [10] apresentou um procedimento para testar hipóteses precisas (hipóteses com medida de Lebesgue nula), que baseia-se no cálculo da probabilidade posterior da Região HPD (Highest Posterior Density) tangente ao conjunto que define a hipótese nula ...
E.L.O. Fernandes +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source