Results 141 to 150 of about 852,985 (355)

Bird flu, avian influenza : the H5N1 virus, poultry, other animals, and people here and elsewhere, from Asia to Africa [PDF]

, 2006
Illustré d'une trentaine de photographies originales issues des missions de terrain des vétérinaires et ornithologues du Cirad dans les pays du Sud, le livret fait le point sur ce fléau qui a d'abord frappé les pays du Sud-Est asiatique depuis 1997 ...
Albina, Emmanuel, Balança, Gilles, Benmansour, Abdenour, Camus, Emmanuel, Cardinale, Eric, Caron, Alexandre, Chevalier, Véronique, De La Rocque, Stéphane, Desvaux, Stéphanie, Gaidet, Nicolas, Gerbier, Guillaume, Goutard, Flavie, Lancelot, Renaud, Martinez, Dominique, Monicat, François, Porphyre, Vincent, Renard, Jean-François, Richard, Didier, Roger, François, Salgado, Paulo, Vial, Laurence   +20 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Genomic Characterization of Clinical Brucella melitensis Isolates from Tunisia: Integration into the Global Population Structure

Microorganisms
Brucellosis represents a significant global health concern that is endemic in many regions of the world, especially in Maghreb (Tunisia, Morocco and Algeria).
Asma Ferjani, Hellen Buijze, Germán Kopprio, Susanne Köhler, Amel Rehaiem, Hajer Battikh, Lamia Ammari, Sana Ferjani, Lamia Kanzari, Meriam Zribi, Badreddine Kilani, Nicolle Hanschmann, Holger Scholz, Ilhem Boutiba   +13 more
doaj   +1 more source

Intra- and interspecies transmission of H7N7 highly pathogenic avian influenza virus during the avian influenza epidemic in the Netherlands in 2003 [PDF]

The poultry epidemic of H7N7 highly pathogenic avian influenza (HPAI) virus in the Netherlands in 2003 was probably the result of the introduction of an H7N7 low pathogenic avian influenza (LPAI) virus (by interspecies transmission from wild birds) and ...
Goot, J.A., van der, Jong, M.C.M., de, Koch, G., Stegeman, J.A.   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Pathogenicity and transmissibility of cow-derived H5N1 highly pathogenic avian influenza viruses

Uirusu
The H5N1 highly pathogenic avian influenza virus (HPAIV) of clade 2.3.4.4b emerged in Europe during 2020-2021 and rapidly spread worldwide via migratory birds, causing outbreaks in poultry, wild birds, and wildlife. Sporadic cases of human infection, likely resulting from close contact with infected animals, have been reported.
Tadashi, Maemura, Yoshihiro, Kawaoka
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A MALDI-ToF mass spectrometry database for identification and classification of highly pathogenic bacteria

Scientific Data
Today, MALDI-ToF MS is an established technique to characterize and identify pathogenic bacteria. The technique is increasingly applied by clinical microbiological laboratories that use commercially available complete solutions, including spectra ...
Peter Lasch, Wolfgang Beyer, Alejandra Bosch, Rainer Borriss, Michal Drevinek, Susann Dupke, Monika Ehling-Schulz, Xuewen Gao, Roland Grunow, Daniela Jacob, Silke R. Klee, Armand Paauw, Jörg Rau, Andy Schneider, Holger C. Scholz, Maren Stämmler, Le Thi Thanh Tam, Herbert Tomaso, Guido Werner, Joerg Doellinger   +19 more
doaj   +1 more source

NO EVIDENCE OF INFECTION OR EXPOSURE TO HIGHLY PATHOGENIC AVIAN INFLUENZAS IN PERIDOMESTIC WILDLIFE ON AN AFFECTED POULTRY FACILITY [PDF]

, 2016
Daniel A. Grear, Robert J. Dusek, Daniel P. Walsh, Jeffrey S. Hall   +3 more
openalex   +1 more source