Results 191 to 200 of about 4,290,191 (312)

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Broadly Protective Antibody-Like Vaccines Against Highly Pathogenic Coronaviruses. [PDF]

J Med Virol
Helal A, Aljehani ND, Ghazwani A, Alsulaiman RM, Alyami F, Abdulaal WH, Alsharef A, Alghanmi M, Zawawi A, Azhari AA, Almehmadi A, Balula J, Altorki T, Alhabbab RY, Khan MY, Alluhaybi K, Alnami A, Neamatallah T, Abujamel TS, Alfaleh MA, Hashem AM.   +20 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Assessment of variant pathogenicity in a highly admixed population [PDF]

Human Mutation, 2017
openaire   +2 more sources

Experimental Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Alpacas, 2026. [PDF]

Emerg Infect Dis
Schön J, Breithaupt A, Halwe NJ, Hertel M, Ahrens AK, Aebischer A, Hoffmann D, Beer M.   +7 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Genomic and pathogenic characterization of a highly pathogenic chicken infectious anemia virus strain in China. [PDF]

Front Vet Sci
Yang H, Yuan L, Chen H, Liu Y, Xu A, Ling Z, Xuan X, Ma S, Feng S, Wang Y, Si H, Li G, Li Y, Zhang A, Ou C.   +14 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Multiple introductions of highly pathogenic avian influenza viruses into the High Arctic: Svalbard and Jan Mayen, 2022-2025. [PDF]

J Gen Virol
Granstad S, Tønnessen R, Ytrehus B, Descamps S, Moe B, Strøm H, Gabrielsen GW, Hanssen SA, Rønning E, Tronerud OH, Loonen MJJE, Gjerset B, Mjelde HK, Madslien K, Åkerstedt J, Bøe CA.   +15 more
europepmc   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source