Results 191 to 200 of about 852,985 (355)

Update on human infections with highly pathogenic avian influenza virus A/H7N7 during an outbreak in poultry in The Netherlands

, 2003
Marion Koopmans, Ron A. M. Fouchier, Berry Wilbrink, Adam Meijer, Gerard Natrop, Albert D. M. E. Osterhaus, Jim van Steenbergen, M Du Ry, M.A.E. Conyn-van Spaendonck, A Bosman   +9 more
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis. [PDF]

Science
Funk M, Spronken MI, Hutchinson RM, Arragain B, Juyoux P, Bestebroer TM, de Bruin ACM, Gultyaev AP, Fouchier RAM, Cusack S, Te Velthuis AJW, Richard M.   +11 more
europepmc   +1 more source

PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection [PDF]

, 2012
Qiang Wang, Shijian Zhang, Hongbing Jiang, Jinlan Wang, Leiyun Weng, Yingying Mao, Satoshi Sekiguchi, Fumihiko Yasui, Michinori Kohara, Philippe Buchy, Vincent Deubel, Ke Xu, Bing Sun, Tetsuya Toyoda   +13 more
openalex   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Detection of highly pathogenic avian influenza A(H5N1) virus 2.3.4.4b in alpacas. [PDF]

J Vet Diagn Invest
Lehman KA, Leibsle SR, Detwiler L, Gaborick C, McCoy-Harrison L, Snekvik K, Lantz K, Torchetti MK, Robbe-Austerman S.   +8 more
europepmc   +1 more source

Additional file 1: of A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture

, 2017
Shoya Iwanami, Yusuke Kakizoe, Satoru Morita, Tomoyuki Miura, Shinji Nakaoka, Shingo Iwami   +5 more
openalex   +1 more source

Persistence of low and highly pathogenic avian influenza virus in reused poultry litter, effects of litter amendment use, and composting temperatures

, 2020
A. Figueroa, Theodore J. Derksen, Sagor Biswas, Ali Nazmi, Daniel Rejmanek, Beate Crossley, Pramod Pandey, Rodrigo A. Gallardo   +7 more
openalex   +1 more source

Benefits of a European Project on Diagnostics of Highly Pathogenic Agents and Assessment of Potential “Dual Use†Issues [PDF]

, 2014
Roland Grunow, Giuseppe Ippolito, Daniela Jacob, Ursula G. Sauer, Anna-Maria Rohleder, Antonino Di, R. Iacovino   +6 more
openalex   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source