Results 1 to 10 of about 1,110 (131)

Association of the HIGS Score With Permanent Pacemaker Implantation and Mortality After Transcatheter Aortic Valve Implantation. [PDF]

Annals of Medicine
Background Permanent pacemaker implantation (PPI) and early mortality remain important complications after transcatheter aortic valve implantation (TAVI).
Ali Orcun Sürmeli, Mehmet Balli, Sonay Oguz   +2 more
exaly   +4 more sources

The MoSR-MoDde1 Regulatory Axis: A Novel Determinant of DMI Sensitivity and a Target for Sustainable Rice Blast Control. [PDF]

Adv Sci (Weinh)
The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Meng FZ, Wei WK, Wu MY, Cai MZ, Wang YF, Zhao L, Meng S, Yin LF, Schnabel G, Yin WX, Luo CX.   +10 more
europepmc   +2 more sources

Determinants of Immune Tolerance Induction Outcomes in 237 Persons With Severe Hemophilia A. [PDF]

Eur J Haematol
ABSTRACT Immune tolerance induction (ITI) to eradicate an immune response against factor VIII (FVIII) has been used in hemophilia A (HA) with various success rates, costs, and treatment burden. The present study aimed to identify markers predictive of ITI success.
Fager Ferrari M, Roslund J, Manderstedt E, Berntorp E, Astermark J, Malmö and Hemophilia Inhibitor Genetics Study Investigators.   +5 more
europepmc   +2 more sources

Host-Induced Gene Silencing of SmDSR32 Enhances Wheat Defense Against Sitobion miscanthi [PDF]

Current Issues in Molecular Biology
The grain aphid, Sitobion miscanthi, poses a serious threat to cereal crops worldwide, leading to considerable yield losses and demanding annual insecticide applications during the grain-filling stage.
Jiahui Zhang, Xue Zhong, Mingxin Cao, Jiajing Xu, Mengchao Qin, Frédéric Francis, Lanqin Xia   +6 more
doaj   +2 more sources

RNAI-based strategies and nanomaterial-mediated delivery for green control of clubroot disease in rapeseed [PDF]

Journal of Advanced Research
Introduction: Clubroot, caused by Plasmodiophora brassicae, threatens crucifers globally. RNAi shows promise for disease control, yet its use against clubroot is unexplored.
Miaomiao Cui, Zanzan Xu, Zheng Shi, Jiasen Cheng, Jiatao Xie, Yang Lin, Yanping Fu, Tom Hsiang, Daohong Jiang, Tao Chen   +9 more
doaj   +2 more sources

Host induced gene silencing of Magnaporthe oryzae by targeting pathogenicity and development genes to control rice blast disease

Frontiers in Plant Science, 2022
Rice blast disease caused by the hemi-biotrophic fungus Magnaporthe oryzae is the most destructive disease of rice world-wide. Traditional disease resistance strategies for the control of rice blast disease have not proved durable.
Mengying Wang, Ralph A. Dean
doaj   +1 more source

Developing neural network diagnostic models and potential drugs based on novel identified immune-related biomarkers for celiac disease

Human Genomics, 2023
Background As one of the most common intestinal inflammatory diseases, celiac disease (CD) is typically characterized by an autoimmune disorder resulting from ingesting gluten proteins. Although the incidence and prevalence of CD have increased over time,
Tao Shen, Haiyang Wang, Rongkang Hu, Yanni Lv   +3 more
doaj   +1 more source

Hematological Inflammatory Gradient Score (HIGS): A Novel Predictor of Early Mortality After Coronary Artery Bypass Grafting [PDF]

Journal of Inflammation Research
Abdülkadir Bilgic, Özkan Karaca, Samet Yılmaz   +2 more
exaly   +2 more sources

Host-induced gene silencing of multiple pathogenic factors of Sclerotinia sclerotiorum confers resistance to Sclerotinia rot in Brassica napus

Crop Journal, 2022
Sclerotinia sclerotiorum is generally considered one of the most economically damaging pathogens in oilseed rape (Brassica napus). Breeding for Sclerotinia resistance is challenging, as no immune germplasm available in B. napus.
Jian Wu, Shengliang Yin, Li Lin, Dongxiao Liu, Sichao Ren, Wenjing Zhang, Wencheng Meng, Peipei Chen, Qinfu Sun, Yujie Fang, Cunxu Wei, Youping Wang   +11 more
doaj   +1 more source

Mobile RNAs—the magical elf traveling between plant and the associated organisms [PDF]

ExRNA, 2019
RNA interfering (RNAi) is mediated by small non-coding RNAs (sRNAs) and efficiently silence gene expression at the posttranscriptional level in eukaryotes.
Shuo Zhang, Zhi Hong
doaj   +1 more source