Results 31 to 40 of about 99,672 (347)

Are mice good models for human neuromuscular disease? Comparing muscle excursions in walking between mice and humans [PDF]

, 2017
The mouse is one of the most widely used animal models to study neuromuscular diseases and test new therapeutic strategies. However, findings from successful pre-clinical studies using mouse models frequently fail to translate to humans due to various ...
A De Luca, A Rajagopal, A Soman, AA Biewener, AA Biewener, AC Ludolph, AEH Emery, AL Camp, AV Birn-Jeffery, BH Wokke, BJ Petrof, C Pastoret, C Webster, CM Consolino, CM Eng, DM Escolar, E Azizi, E Mok, EK Moo, EM Arnold, EM Arnold, EM Arnold, FA Jenkins, FE Zajac, GM Buyse, GT Carter, H Radley-Crabb, H Stedman, HB van der Worp, HM Hsieh-Li, IG Kirkinezos, J Manning, JA Granchelli, JA Vilensky, JH Veldink, JJ Kaczor, JK Mah, JN Kornegay, JN Kornegay, JP Charles, JP Charles, JR Chamberlain, JW Carnwath, JW McGreevy, KA Clarke, KN An, L Xu, LM Ittner, M Benatar, M Bodor, M Millard, MD Grounds, MD Klein Horsman, ME Gurney, ME Llewellyn, MP Kadaba, N Alexander, N Serradj, NP Whitehead, P DeVita, P Moens, P Sicinski, R Burdi, R Willmann, R Willmann, RH Miller, RW Burgess, SL Delp, SL Delp, SR Ward, SS Blemker, SV Brooks, T Akay, TA McMahon, TA Partridge, TS Buchanan, V Brussee, VC Henderson, X Chen, X Chen, X Hu, ZJ Domire   +81 more
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Chronic Hindlimb Ischemia Assessment; Quantitative Evaluation Using Laser Doppler in a Rodent Model of Surgically Induced Peripheral Arterial Occlusion

Diagnostics, 2019
Therapeutic neoangiogenesis (TNA) holds promise as a treatment for peripheral arterial disease. Nevertheless, proper tools for in vivo pre-clinical investigation of different TNA approaches and their effects are still lacking.
Bogdan Hoinoiu, Lucian Petru Jiga, Alexandru Nistor, Vlad Dornean, Sorin Barac, Gratian Miclaus, Mihai Ionac, Teodora Hoinoiu   +7 more
doaj   +1 more source

Denervation in Femoral Artery-Ligated Hindlimbs Diminishes Ischemic Recovery Primarily via Impaired Arteriogenesis. [PDF]

PLoS ONE, 2016
AIMS:Multiple factors regulate arteriogenesis. Peripheral nerves play a crucial role in vascular remodeling, but the function of peripheral nerves during arteriogenesis is obscure.
Yinghuan Cen, Junfeng Liu, Yuansen Qin, Ruiming Liu, Huijin Wang, Yu Zhou, Shenming Wang, Zuojun Hu   +7 more
doaj   +1 more source

Turtle Flexion Reflex Motor Patterns Show Windup, Mediated Partly by L-type Calcium Channels

Frontiers in Neural Circuits, 2017
Windup is a form of multisecond temporal summation in which identical stimuli, delivered seconds apart, trigger increasingly strong neuronal responses. L-type Ca2+ channels have been shown to play an important role in the production of windup of spinal ...
Keith P. Johnson, Stephen M. Tran, Emily A. Siegrist, Krishna B. Paidimarri, Matthew S. Elson, Ari Berkowitz, Ari Berkowitz   +6 more
doaj   +1 more source

The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis [PDF]

, 2018
Diabetic vascular complications are associated with impaired ischaemia-driven angiogenesis. We recently found that reconstituted high-density lipoproteins (rHDL) rescue diabetes-impaired angiogenesis.
Bursill, Christina A., Clayton, Zoe E., Henriquez, Rodney, Hourigan, Samuel T., Nankivell, Victoria A., Ng, Martin K.C., Nicholls, Stephen J., Ridiandries, Anisyah, Robertson, Stacy, Solly, Emma L., Tan, Joanne T.M., Tepper, Edward R., Tsatralis, Tania, Vanags, Laura Z., Weimann, Benjamin M., Zhang, Jennifer Q.J.   +15 more
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Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery

Scientific Reports, 2018
Peripheral ischemia is associated with higher degree of endothelial dysfunction and a worse prognosis after percutaneous coronary interventions (PCI).
S. Sorrentino, C. Iaconetti, S. De Rosa, A. Polimeni, J. Sabatino, C. Gareri, Francesco Passafaro, Teresa Mancuso, Laura Tammè, C. Mignogna, C. Camastra, G. Esposito, A. Curcio, D. Torella, C. Indolfi   +14 more
semanticscholar   +1 more source

Influence of seating styles on head and pelvic vertical movement symmetry in horses ridden at trot [PDF]

, 2018
Detailed knowledge of how a rider’s seating style and riding on a circle influences the movement symmetry of the horse’s head and pelvis may aid rider and trainer in an early recognition of low grade lameness. Such knowledge is also important during both
Haubro Andersen, P, Hernlund, E, Persson-Sjodin, E, Pfau, T, Rhodin, M   +4 more
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Candidate Regulatory Genes for Hindlimb Development in the Embryos of the Chinese Alligator (Alligator sinensis)

Animals, 2023
Crocodilians, which are a kind of animal secondary adaptation to an aquatic environment, their hindlimb can provide the power needed to engage in various life activities, even in low-oxygen water environments.
Liuyang Yang, Mengqin Liu, Yunzhen Zhu, Yanan Li, Tao Pan, En Li, Xiaobing Wu   +6 more
doaj   +1 more source

Curcumin induces therapeutic angiogenesis in a diabetic mouse hindlimb ischemia model via modulating the function of endothelial progenitor cells

Stem cell research & therapeutics, 2017
Neovascularization is impaired in diabetes mellitus, which leads to the development of peripheral arterial disease and is mainly attributed to the dysfunction of endothelial progenitor cells (EPCs).
Jinzhi You, Jiacheng Sun, T. Ma, Ziying Yang, Xu Wang, Zhiwei Zhang, Jingjing Li, Longgang Wang, Masaaki Ii, Junjie Yang, Zhenya Shen   +10 more
semanticscholar   +1 more source

Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice [PDF]

, 2016
Background: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular ...
Bursill, Christina A., Lam, Yuen Ting, Ng, Martin K. C., Ridiandries, Anisyah, Robertson, Stacy, Tan, Joanne T. M., Tsatralis, Tania, Vanags, Laura Z.   +7 more
core   +2 more sources