Results 161 to 170 of about 41,234 (255)

Long-term predictors of seizure outcome after anterior temporal lobectomy in unilateral hippocampal sclerosis: A 281-patient cohort with mean 10-year follow-up. [PDF]

Epileptic Disord
Rodrigues TP, Bocca LF, Yacubian EMT, Guaranha MSB, Alonso NB, Junior HC, Noffs MHS, Caboclo LO, Duarte JTC, Centeno RS.   +9 more
europepmc   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, Volume 99, Issue 3, Page 809-824, March 2026.
A[Color figure can be viewed at www.annalsofneurology.org] Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

<i>TMEM14A</i> Gene Affects Hippocampal Sclerosis in Mesial Temporal Lobe Epilepsy. [PDF]

J Clin Med
Kim J, Cho S, Jeong KH, Ha WS, Kim KM, Chu MK, Lee JH, Kim S, Kim WJ.   +8 more
europepmc   +1 more source

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

Annals of Neurology, Volume 99, Issue 3, Page 614-628, March 2026.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl, We Fong Siah, Efstratios Karavasilis, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Foteini Christidi, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Hippocampal sclerosis in association with Sturge-weber syndrome: An intertwining of 2 epileptogenic lesions. [PDF]

Radiol Case Rep
AlAlwan MQ, Alsaad FA, Alhashem HY, Altaweel I, AlAlwan QM, Al Obaid JJ, Almohammed Ali HA.   +6 more
europepmc   +1 more source

Associations Between Cardiovascular Risk Factors and Neurofilament Light Levels Among US Mexican American Adults

Brain and Behavior, Volume 16, Issue 3, March 2026.
These findings suggest NfL's potential as a prognostic biomarker for CVD and neurodegeneration, especially in MA adults. Further research is needed to understand these associations and develop targeted prevention strategies for brain aging disparities. ABSTRACT Background This study explores the relationship between neurofilament light (NfL) levels, a ...
Monica M. Diaz, Eran Dayan, Health and Aging Brain Study – Health Disparities (HABS‐HD) Study   +2 more
wiley   +1 more source

Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy. [PDF]

J Physiol
Wu Z, Henning L, Steinhäuser C, Bedner P.   +3 more
europepmc   +1 more source

MCC‐135 Exerts Antiepileptic and Neuroprotective Effects by Downregulating NCX1 Expression to Decrease Intracellular Calcium Overload in the Hippocampus

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
MCC‐135 treatment significantly prolonged the seizure latency and alleviated hippocampal neuronal damage in KA‐induced epileptic mice. Furthermore, MCC‐135 reduced NCX1 levels, alleviated intracellular calcium overload, and downregulated glutamate levels in the epileptic mice.
Chaoning Liu, Min He, Rida Li, Shouhuan Zheng, Lanfeng Sun, Chi Gong, Hengchang Qi, Xinran Qin, Xiaohang Gan, Fang Wang, Yuan Wu   +10 more
wiley   +1 more source

Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis. [PDF]

Ann Clin Transl Neurol
Iwata T, Yanagisawa T, Fukuma R, Ikegaya Y, Oshino S, Tani N, Khoo HM, Sugano H, Iimura Y, Suzuki H, Kishima H.   +10 more
europepmc   +1 more source