Results 161 to 170 of about 81,056 (343)

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Variability of sclerosis along the longitudinal hippocampal axis in epilepsy: A post mortem study

, 2012
Maria Thom, Ioannis Liagkouras, Lillian Martinian, Joan Liu, Claudia B. Catarino, Sanjay M. Sisodiya   +5 more
openalex   +1 more source

The use of hippocampal volumetric measurements to improve diagnostic accuracy in pediatric patients with mesial temporal sclerosis [PDF]

, 2017
Gloria Guzmán, Christopher Owen, Katherine E. Schwetye, Spencer McFarlane, Ananth K. Vellimana, Soe Mar, Michelle Miller‐Thomas, Joshua S. Shimony, Matthew D. Smyth, Tammie L.S. Benzinger   +9 more
openalex   +1 more source

Diagnostic performance of neuroimaging modalities for epileptogenic focus localization: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Accurate localization of epileptogenic foci remains of significant importance for surgical planning in drug‐resistant epilepsy. Multiple neuroimaging modalities are available; however, their comparative diagnostic performance lacks comparative detailed synthesis.
Mustafa S. Alhasan, Mohammed Khalil, Ayman S. Alhasan, Ahmed Najjar, Yasir Hassan Elhassan, Abdullah Almaghraby, Omar Alharthi, Seham Hamoud, Muhammed Amir Essibayi, Fabricio Feltrin, Sumit Singh, James Milburn, Ahmed Y. Azzam   +12 more
wiley   +1 more source

Consanguinity in patients with mesial temporal lobe epilepsy due to hippocampal sclerosis in a Saudi population [PDF]

, 2020
Khalid Alqadi, Saba A. Rammal, Mosaab E. Alam, Ashwaq Alshahrani, Saleh Baeesa, Husam Kayyali, Fawzi Babtain, Youssef Al-Said   +7 more
openalex   +1 more source

Predictors of etiology and drug resistance in children with new‐onset focal seizures

Epilepsia Open, EarlyView.
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee, Russell C. Dale, Elizabeth H. Barnes, Shekeeb S. Mohammad, Sachin Gupta, Chong Wong, Deepak Gill, Kavitha Kothur   +7 more
wiley   +1 more source

Response: Hippocampal Sclerosis [PDF]

Epilepsia, 2004
Adrian Lowe, Christine Kilpatrick, Terence J. O'Brien   +2 more
openaire   +1 more source

Thalamic–hippocampal–prefrontal disruption in relapsing–remitting multiple sclerosis

, 2014
Kyle C. Kern, Stefan M. Gold, Brian Lee, Michael Montag, Jessica L. Horsfall, Mary‐Frances O'Connor, Nancy L. Sicotte   +6 more
openalex   +1 more source

Late‐onset unexplained epilepsy as a risk factor for cognitive impairment and dementia: Protocol for a multi‐center prospective longitudinal observational study (ELUCID)

Epilepsia Open, EarlyView.
Abstract Objective Late‐onset unexplained epilepsy (LoUE), defined as epilepsy onset after age 55 without an obvious cause, is an important risk factor for dementia. Studies have shown that 10%–25% of individuals with LoUE develop dementia within 3–4 years following their first seizure.
Alice D. Lam, Emily L. Johnson, Rani A. Sarkis, Leah J. Blank, Tyler E. Gaston, Mouhsin M. Shafi, Rodrigo Zepeda, Kyle R. Pellerin, Nathalie Jette, Douglas N. Greve, Lori B. Chibnik, Rebecca E. Amariglio, Gad A. Marshall, M. Brandon Westover   +13 more
wiley   +1 more source

Ultra‐refractory epilepsy: The newly described entity

Epilepsia Open, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) is defined as the failure of two antiseizure medications (ASMs) to achieve complete seizure control, affecting approximately 30% of epilepsy patients. In some cases, additional ASMs and surgical approaches are also unsuccessful.
Jan Vinklárek, Petra Búřilová, Mojdeh Raouf Zadeh, Eva Zatloukalová, Jitka Kočvarová, Ondřej Strýček, Martin Pail, Klára Štillová, Jan Chrastina, Eva Brichtová, Andrea Pokorná, Dana Mazánková, Milan Brázdil, Irena Doležalová   +13 more
wiley   +1 more source