Results 101 to 110 of about 335,737 (319)

Pattern Separation in a Spiking Neural Network of Hippocampus Robust to Imbalanced Excitation/Inhibition [PDF]

open access: yesarXiv, 2018
Efficient pattern separation in dentate gyrus plays an important role in storing information in the hippocampus. Current knowledge of the structure and function of the hippocampus, entorhinal cortex and dentate gyrus, in pattern separation are incorporated in our model. A three-layer feedforward spiking neural network inspired by the rodent hippocampus
arxiv  

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

Comprehensive study on influence of low dose chronic consumption of silver nanoparticles on cognitive functions and identification of the effect reasons [PDF]

open access: yesarXiv, 2018
The influence of the daily prolonged administration of silver nanoparticles on cognitive functions of model mammals was studied. The accumulation of silver in whole brain, hippocampus, cerebellum, cortex and residual part of mice brain was investigated by highly precise and representative Neutron Activation Analysis and the histological studies were ...
arxiv  

Thermally Drawn Shape and Stiffness Programmable Fibers for Medical Devices

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Thermal drawing technique is adapted to fabricate Shape Memory Polymer Fibers (SMPFs) with programmable stiffness and shape. Multilumen and multimaterial SMPFs are developed for innovative medical devices: stiffness adjustable catheters, body temperature softening neural interfaces, and shape programmable cochlear implants.
Jiwoo Choi   +16 more
wiley   +1 more source

Enhancement Mask for Hippocampus Detection and Segmentation [PDF]

open access: yes2018 IEEE International Conference on Information and Automation (ICIA), 2019
Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently detects and segments the hippocampal structures.
arxiv  

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Hippocampus: Remembering the Choices [PDF]

open access: yesNeuron, 2013
The hippocampus is said to be involved in "navigation" and "memory" as if these were distinct functions. In this issue of Neuron, Singer et al. (2013) provide evidence that the hippocampus retrieves spatial sequences in support of memory, strengthening a convergence between the two perspectives on hippocampal function.
openaire   +3 more sources

Transparent Temperature Sensors for Photothermal Neuromodulation: Advances, Challenges, and Future Directions

open access: yesAdvanced Materials Interfaces, EarlyView.
Photothermal neuromodulation is a promising technique for versatile neural signal study and treatment development. To further develop these technologies and optimize their effectiveness, transparent electrical temperature sensors with high thermal sensitivity and resolution are essential for accurately monitoring temperature changes during ...
Jee Woong Lee   +7 more
wiley   +1 more source

A Flexible‐Substrate 5‐µm‐Diameter Needle Electrode: Minimizing Neuronal Death and Enabling Year‐Long Neural Recording

open access: yesAdvanced Materials Interfaces, EarlyView.
An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki   +6 more
wiley   +1 more source

SPECT and MRI study in patients with temporal lobe epilepsy caused by hippocampal sclerosis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To analyze the changes of hippocampus blood perfusion and hippocampal volume in patients with temporal lobe epilepsy (TLE) caused by hippocampal sclerosis (HS) using single-photon emission-computed tomography (SPECT) and MRI, so as to ...
Le GUAN   +5 more
doaj  

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