Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Advanced Science, EarlyView.Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin +9 more
wiley +1 more source
Hebbian imprinting and retrieval in oscillatory neural networks [PDF]
Neural Computation 14, 2371 (2002)., 2001 We introduce a model of generalized Hebbian learning and retrieval in oscillatory neural networks modeling cortical areas such as hippocampus and olfactory cortex. Recent experiments have shown that synaptic plasticity depends on spike timing, especially on synapses from excitatory pyramidal cells, in hippocampus and in sensory and cerebellar cortex ...
arxiv
MOTOR NERVE ENDINGS OF TWITCH MUSCLE FIBERS IN HIPPOCAMPUS HUDSONIUS [PDF]
, 1967 Ronald A. Bergman
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Advanced Science, EarlyView.New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang +10 more
wiley +1 more source
Hippocampus Temporal Lobe Epilepsy Detection using a Combination of Shape-based Features and Spherical Harmonics Representation [PDF]
arXiv, 2016 Most of the temporal lobe epilepsy detection approaches are based on hippocampus deformation and use complicated features, resulting, detection is done with complicated features extraction and pre-processing task. In this paper, a new detection method based on shape-based features and spherical harmonics is proposed which can analysis the hippocampus ...
arxiv
Advanced Science, EarlyView.S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin +7 more
wiley +1 more source
The Frequent Network Neighborhood Mapping of the Human Hippocampus Shows Much More Frequent Neighbor Sets in Males Than in Females [PDF]
arXiv, 2018 In the study of the human connectome, the vertices and the edges of the network of the human brain are analyzed: the vertices of the graphs are the anatomically identified gray matter areas of the subjects; this set is exactly the same for all the subjects. The edges of the graphs correspond to the axonal fibers, connecting these areas.
arxiv
The effect of absence of the corpus callosum on the position of the hippocampus and on the formation of Probst's bundle [PDF]
, 1961 Kenneth R. Magee, Robert N. Olson
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Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
Advanced Science, EarlyView.This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu +15 more
wiley +1 more source
Blood pressure, pulse, and respiratory changes produced by stimulation of the hippocampus of the monkey [PDF]
, 1963 Charles L. Votaw, Edward W. Lauer
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