Results 131 to 140 of about 310,272 (392)

Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets

ESC Heart Failure, EarlyView.
Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley   +1 more source

Evaluation of the Histamine Content and Potential Toxicity of Some of Consumable food

Armaghane Danesh Bimonthly Journal, 2017
Background & aim: Consuming high amounts of histamine with food causes histamine poisoning among its consumers. Much information about the content of histamine in various food products is not available in the country.
M Zarei, A Fazlara, F Zarezadeh
doaj  

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F., Gilles, Stefanie, Sommerhoff, Christian P., Welsch, Ulrich, Zahler, Stefan   +4 more
core   +1 more source

Synthesis of Substituted Imidazo[1,2‐a]pyridines, Imidazo[1,2‐a]pyrazines and Imidazo[1,2‐b]pyridazines by Multicomponent Reactions Using Green Solvents.

European Journal of Organic Chemistry, Accepted Article.
Here we describe the synthesis of imidazo[1,2‐a]pyridines, imidazo[1,2‐a]pyrazines and imidazo[1,2‐b]pyridazines by multicomponent Groebke‐Blackburn‐Bienaymé (GBB) reaction under sustainable conditions using eucalyptol as green solvent. After determining the optimum conditions for catalysis, a library of 32 compounds with activity on the central ...
Sabine Berteina-Raboin, Abdelkarim El-Qami, Gatien Messire, Gaëtan Bouchery, Emma Caillet, Sloan Steiner   +5 more
wiley   +1 more source

The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer [PDF]

, 2014
Although there is increasing appreciation of the role of the host inflammatory response in determining outcome in patients in colorectal cancer, there has been little concerted effort to favourably manipulate cancer-associated inflammation, either alone ...
Horgan, P.G., McMillan, D.C., Park, J.H., Roxburgh, C.S.   +3 more
core   +1 more source

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission [PDF]

, 2016
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa.
A Musoke, A Musoke, AR Trimnell, AR Trimnell, AR Walker, AS Bowman, AS Young, AS Young, B Minjauw, C Almazán, C Almazán, C Almazán, C Almazán, CA Ferreira, Cassandra L. Olds, CL Schwartzkoff, Claudia Daubenberger, David O. Odongo, DO Odongo, DO Odongo, G Büscher, GC Paesen, GJ Rowlands, Glen A. Scoles, H Ochanda, I Couillin, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Fuente de la, J Katende, JD Hunt, JD Hunt, JG Valenzuela, JH Pruett, JM Ribeiro, JO Adejinmi, K Bailey, KM Kocan, M Labuda, M Saimo, M Shakya, MP Szabó, NA Steen, NH Ogden, O Merino, O Merino, P Willadsen, P Willadsen, P Willadsen, PG Toye, R Bishop, R Bishop, RA Skilton, RAI Norval, RC Galindo, Richard Bishop, S Havlíková, SK Wikel, Stephen Mwaura, T Bazarusanga, T Schetters, TT Dolan, V Nene, Z Zivkovic   +65 more
core   +3 more sources

Inducible and titratable silencing of Caenorhabditis elegans neurons in vivo with histamine-gated chloride channels

Proceedings of the National Academy of Sciences of the United States of America, 2014
Significance Inducible silencing of neurons is a powerful method for studying the functions of neural circuits. We describe a system for inducible silencing of Caenorhabditis elegans neurons, based on transgenic C. elegans nematodes engineered to produce
N. Pokala, Q. Liu, A. Gordus, Cori Bargmann   +3 more
semanticscholar   +1 more source

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling

iMeta, EarlyView.
Compared to healthy controls, children with food‐sensitized tolerance and food allergy showed reduced fecal short‐chain fatty acids (SCFAs), particularly butyrate. In an ovalbumin‐sensitized mouse model, butyrate outperformed other SCFAs in alleviating allergic responses.
Jialu Shi, Wenjun Mao, Yuqing Song, Yuxin Wang, Lili Zhang, Yan Xu, Huiwen Gu, Siyu Yao, Yuanhang Yao, Zhifeng Liu, Vijaya Raghavan, Jin Wang   +11 more
wiley   +1 more source

Progress in Allergy Signal Research on Mast Cells: The Role of Histamine in Immunological and Cardiovascular Disease and the Transporting System of Histamine in the Cell

Journal of Pharmacological Sciences, 2008
Since its discovery in 1910, histamine has been regarded as one of the most important biogenic amines in the medical and biological fields. This article summarizes the information about the role of histamine in allergic situations, atherosclerosis, and ...
Hiroshi Ohtsu
doaj  

Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze

Brazilian Journal of Medical and Biological Research, 1997
The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj   +1 more source