Mast Cell Mediators in Citric Acid-Induced Airway Constriction of Guinea Pigs
, 2009 We demonstrated previously that mast cells play an important role in citric acid (CA)-induced airway constriction. In this study, we further investigated the underlying mediator( s) for this type of airway constriction.
林健合;賴義隆 +1 more
core
Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells
Allergy, EarlyView.We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller +16 more
wiley +1 more source
Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
Allergy, EarlyView.This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes +11 more
wiley +1 more source
Histamine-Mediated Syndrome (HMS): Beyond Allergy and Therapeutic Potential of Immunoglobulin/Histamine Complex (IHC). [PDF]
Int J Mol SciKim HS, Noh G.
europepmc +1 more source
Allergy, EarlyView.Histamine infusions induce reproducible severe hypotension. Intramuscular adrenaline showed ‘supposedly therapeutic’ plasma concentrations but did not produce a sustained clinically relevant improvement in shock in the majority of recipients. These findings question adrenaline pharmacokinetic surrogate thresholds and support the need for faster and ...
Matthias Weiss‐Tessbach +12 more
wiley +1 more source
Sanguinarine Alleviates the Adverse Effects of Excessive Dietary Histamine on Growth and Intestinal and Hepatic Health in Juvenile American Eels (<i>Anguilla rostrata</i>). [PDF]
Animals (Basel)Xu Y +5 more
europepmc +1 more source
Isolation of histamine using -Fe2O3 nanoparticles
, 2019 Histamine, biologically active amine, is normally present in the body and it is involved in a local regulation of physiological processes. It occurs in food as a product of microbial decarboxylation of the amino acid histidine, and the ingestion of foods
Milosavljević, Vedran +7 more
core
The Evolution of Sesame Seed Allergy Over Time
Allergy, EarlyView.This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong +14 more
wiley +1 more source
Neuroinflammatory Remodeling by Type 2 Immune Pathways Links Allergic Signaling to Neurodegenerative Disease. [PDF]
CellsSchuldt ON +4 more
europepmc +1 more source
Indestructible micro identification of histamine in fish samples using ATR-FTIR spectroscopy
The decarboxylation of histidine can form histamine. It is a heterocyclic amine that is very poisonous if consumed more than 50 ppm per day. The histamine investigation in food is imperative owing to the poisons of histamine.
Muhammad Abdurrahman, Munir +3 more
core +1 more source