Results 281 to 290 of about 310,272 (392)

Smartphone application‐delivered cognitive behavioural therapy for insomnia with telephone support for insomnia disorder compared to a waitlist control: a randomised clinical trial

open access: yesJournal of Sleep Research, EarlyView.
Summary Although there have been promising findings for smartphone application (app)‐delivered cognitive behavioural therapy for insomnia (CBT‐I), previous trials have not screened participants rigorously for insomnia disorder and used therapist support.
Markus Jansson‐Fröjmark   +1 more
wiley   +1 more source

Pitolisant 40 mg for excessive daytime sleepiness in obstructive sleep apnea patients treated or not by CPAP: Randomised phase 3 study

open access: yesJournal of Sleep Research, EarlyView.
Summary Obstructive sleep apnea (OSA) syndrome commonly leads to excessive daytime sleepiness (EDS). Pitolisant, a selective histamine‐3 receptor antagonist, is efficacious at doses up to 20 mg once daily in OSA treated or not with continuous positive airway pressure (CPAP).
Yves Dauvilliers   +20 more
wiley   +1 more source

MRI‐based surrogates of brain clearance in narcolepsy type 1

open access: yesJournal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese   +6 more
wiley   +1 more source

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