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Histamine and the hypothalamus

Neuroscience, 1983
The chemical tools that could be used to examine the function of histamine in the brain are considered together with the evidence linking histamine specifically with the hypothalamus. The distribution of histamine and the enzymes responsible for its synthesis and metabolism is consistent with there being both mast cells and histaminergic nerve ...
F. Roberts, C.R. Calcutt
openaire   +3 more sources

Histamine and Histamine Receptors in Allergic Dermatitis

2016
In this chapter we will first introduce the pathophysiological process of several skin diseases including allergic dermatitis, a common skin disease, including chronic allergic contact dermatitis (CACD), and atopic dermatitis (AD). In CACD and AD patients, repeated skin exposure to antigens contributes to the development of chronic eczematous lesions ...
Masahiro Seike, Hiroshi Ohtsu
openaire   +3 more sources

Histamine in the nervous system.

Physiological Reviews, 2008
Histamine is a transmitter in the nervous system and a signaling molecule in the gut, the skin, and the immune system. Histaminergic neurons in mammalian brain are located exclusively in the tuberomamillary nucleus of the posterior hypothalamus and send ...
H. Haas, O. Sergeeva, O. Selbach
semanticscholar   +1 more source

Histamine, histamine receptors, and anti-histamines in the context of allergic responses

LymphoSign Journal, 2019
Histamine is a bioactive amine which is considered a key player in the allergic response. Thus, histamine receptor blockers (antihistamines) play an important role in the treatment of a number atopic diseases such as allergic rhinitis, conjunctivitis, and acute and chronic forms of urticaria.
Amarilla B. Mandola   +2 more
openaire   +2 more sources

Histamine and Methyl-Histamine

1995
Histamine is widely distributed throughout all tissues although its main sites of synthesis and storage are the tissue mast cell and the blood basophil. Histamine is synthesized from histidine by a specific decarboxylase and stored in the secretory granules. On activation of the cells histamine is released by degranulation.
openaire   +2 more sources

Comparison of human bronchial muscle responses to histamine in vivo with histamine and isoproterenol agonists in vitro.

American Review of Respiratory Disease, 2015
In an effort to explain the large variation of airway reactivity to histamine in human subjects in vivo, we have examined the relationship between histamine responses in vivo and isoproterenol in vitro.
J. Cerrina   +5 more
semanticscholar   +1 more source

Comparison of in vivo and in vitro responses to histamine in human airways.

American Review of Respiratory Disease, 2015
The study was designed to compare in vivo responses to histamine in 14 patients prior to thoracotomy with in vitro responses to histamine of both parenchymal and bronchial tissue.
K. Vincenc   +5 more
semanticscholar   +1 more source

Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways.

American Review of Respiratory Disease, 2015
Terfenadine (Seldane) is a new, highly potent H1 histamine receptor antagonist that in clinically effective doses is free of side effects. Because the low potency and specificity of many H1 receptor antagonists have made it difficult to define the ...
P. Rafferty, S. Holgate
semanticscholar   +1 more source

Histamine and Appetite

2016
Our survival relies on the ability to search for food to attend immediate metabolic needs and to store excess energy in the form of fat to meet metabolic demands during fasting. Hunger and satiety are key factors driving eating behavior and are under control of a complex interplay of several central and peripheral neuroendocrine systems.
Provensi G., Blandina P., Passani M. B.
openaire   +3 more sources

The effects of preferential deposition of histamine in the human airway.

American Review of Respiratory Disease, 2015
Two inhalation techniques were performed to obtain airway and diffuse airway deposition of histamine aerosol. A radiotracer method was used to confirm the patterns of aerosol deposition and to measure the dose of histamine aerosol in the airways.
R. Ruffin   +3 more
semanticscholar   +1 more source

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