Results 111 to 120 of about 46,942 (270)

Direct and indirect trade‐offs between resistance, growth and reproduction in the Japanese stinging nettle Urtica thunbergiana

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Most studies of trade‐offs between defence, growth and reproduction have examined pairwise correlations between these processes, used ratio‐based measures for defence allocation such as allelochemical concentration and trichome density and estimated resource allocation ...
Inori Yuuzaki, Minami Oishi, Hiroaki Sato   +2 more
wiley   +1 more source

A Case Report of Angioedema and Anaphylactic Shock Induced by Ingestion of Polyethylene Glycol [PDF]

, 2020
Introduction: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG).Case Report: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension ...
Osborn, Lesley, Rossi, Amy
core  

Examining the predictive validity of alcohol‐seeking following punishment‐imposed abstinence in mice

Alcohol, Clinical and Experimental Research, EarlyView.
Animal models of alcohol use disorder are critical to understand the neurochemical mechanisms underlying this disorder to inform targeted medication development. However, quite often the validity of commonly used animal models remains untested. Here, we optimized a highly used model of abstinence in mice and demonstrated the predictive validity of the ...
Linh Tran, Maria Kuznetsova, Elizabeth E. Manning, Erin J. Campbell   +3 more
wiley   +1 more source

Alterations in histamine responses between juvenile and adult urinary bladder urothelium, lamina propria and detrusor tissues [PDF]

, 2020
Chess-Williams, Russ, Moro, Christian, Stromberga, Zane   +2 more
core   +1 more source

Blocking Histamine H1 Improves Learning and Mnemonic Dysfunction in Mice With Social Isolation Plus Repeated Methamphetamine Injection

Journal of Pharmacological Sciences, 2008
The aim of this study was to investigate the effects of histamine H1 and H3 antagonists on learning and mnemonic dysfunction in mice. Two H1 antagonists, pyrilamine and clozapine, and the prototypic H3 antagonist thioperamide were used to study the role ...
Feiyong Jia, Jalal Izadi Mobarakeh, Hongmei Dai, Motohisa Kato, Ajing Xu, Tomohiro Okuda, Eiko Sakurai, Nobuyuki Okamura, Kazuhiro Takahashi, Kazuhiko Yanai   +9 more
doaj  

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

Allergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka, Jitesh Chauhan, Silvia Crescioli, Sheila M. McSweeney, Amy Pope, Cheryl Gillett, Ashley Di Meo, Ioannis Prassas, Roman Laddach, Katie Stoker, Alexandra J. McCraw, Rebecca Adams, Thomas J. Tull, Nabeel Naban, Zena Willsmore, Kristina V. Semkova, Clive E. H. Grattan, John McGrath, Stephen J. Till, Christopher J. Corrigan, Rebecca Kristeleit, Sophia Tsoka, Eleftherios P. Diamandis, Katie E. Lacy, Sarah Pinder, Debra H. Josephs, James Spicer, Heather J. Bax, Sophia N. Karagiannis   +28 more
wiley   +1 more source

Effect of an antiandrogenic H2 receptor antagonist on hepatic regeneration in rats [PDF]

, 1988
Because biochemical 'feminization' of the liver in males is observed with hepatic regeneration and because the hepatic regenerative response in females is greater than that in males, the posibility that antiandrogens might potentiate liver regeneration ...
Chapchap, P, Eagon, PK, Kahn, D, Makowka, L, Podesta, L, Starzl, TE, Svanas, GW, Van Thiel, DH   +7 more
core  

Exercise Recommendations and Practical Considerations for Asthma Management—An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Exercise is an important treatment for people with asthma and should be considered alongside pharmacological therapy when developing personalised asthma management plans. Despite this, there remains limited guidance concerning the practicalities of asthma‐specific exercise prescription.
Oliver J. Price, Nikolaos G. Papadopoulos, Darío Antolín Amérigo, Vibeke Backer, Valérie Bougault, Stefano Del Giacco, Radoslaw Gawlik, Ibon Eguiluz‐Gracia, Enrico Heffler, Christer Janson, Vanessa M. McDonald, André Moreira, Andrew Simpson, Matteo Bonini   +13 more
wiley   +1 more source

Helicobacter pylori: types of diseases, diagnosis, treatment and causes of therapeutic failure [PDF]

, 2016
Acute upper gastrointestinal lesions have a multifactorial etiology but, regardless of the cause, they are related to mucosal barrier destruction. Since Helicobacter pylori induces a superficial chronic gastritis with the infiltration of neutrophils in ...
Ciorbagiu, Mihai Calin, Mirea, Cecil Sorin, Moraru, Emil, Obleaga, Cosmin Vasile, Valcea, Ionica Daniel, Vere, Cristin Constantin   +5 more
core   +3 more sources