Results 201 to 210 of about 28,885 (301)

Repurposing the antihistamine cyproheptadine for osteoarthritis: nothing to sneeze at. [PDF]

J Clin Invest
Loeser RF, Coryell PR.
europepmc   +1 more source

Deprescription of Psychotropics in Children and Adolescents: Systematic Review of Guidelines and Development of a Deprescribing Algorithm

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Background Psychotropics are increasingly prescribed in paediatrics despite limited evidence regarding their benefits and effectiveness. Although deprescribing approaches are established in adults, structured paediatric strategies remain poorly defined.
Paul‐Benoît Fargier, Mark Horowitz, Rodolphe Charles, Valérie Rousselon, Erik Fakra, Marie‐Noëlle Beyens, Marie‐Laure Laroche   +6 more
wiley   +1 more source

Pitolisant disrupts memory consolidation and hippocampal synaptic plasticity: Impaired excitability and long-term potentiation in the CA1 area. [PDF]

Iran J Basic Med Sci
Beheshti S, Badiyifard A, Badiei Darani Z, Azimzadeh M, Halabian A.   +4 more
europepmc   +1 more source

Analysis of the Clinical Application Value of Immune Function Markers and Cytokines in the Recurrent Aphthous Ulcer

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Background This study aimed to analyze the alterations in cellular and humoral immune functions, alongside cytokine profiles, in patients with recurrent aphthous ulcer (RAU) compared to those with other oral mucosal diseases and healthy controls (HC), and to investigate their clinical significance.
Yiwen Chen, Ting Meng, Lahong Zhang, Qiang Ke   +3 more
wiley   +1 more source

The dual G9a inhibitor and histamine H3 receptor antagonist A-366 improves repetitive and social behaviors and attenuates neuroinflammation in BTBR T + tf/J mice. [PDF]

Sci Rep
Hajar M, Jayaprakash P, Stark H, Sadek B.   +3 more
europepmc   +1 more source

Rupatadine Ameliorates Cisplatin‐Induced Hepatotoxicity in Rats: Targeting HMGB1/TLR4/NF‐κB and NLRP3/Caspase‐1 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Graphical representation of the probable mechanisms underlying the effect of RUPA on CISP‐evoked hepatotoxicity in rats. ABSTRACT Despite cisplatin (CISP) is broadly employed in cancer therapy, its adverse effects, involving hepatotoxicity, restrict its clinical usage.
Shaimaa Mohamed Abdelrahman, Amany Abdlrehim Bekhit, Olivia N. Beshay   +2 more
wiley   +1 more source

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

When the brain talks back to the eye. [PDF]

PLoS Biol
Gonschorek D, Euler T.
europepmc   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, Volume 41, Issue 4, Page 1048-1060, August 2026.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Tic disorders and allergic diseases: mechanistic links and the impact of allergy management - a narrative review. [PDF]

Front Allergy
Li L, Hu W, Ren Y, Zhang H, Zhu S, Zhong T, Zhang H.   +6 more
europepmc   +1 more source