Results 201 to 210 of about 26,153 (259)
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Histamine, histamine antagonists and regional blood flow
European Journal of Pharmacology, 1977The effects of mepyramine, a selective histamine H1-receptor antagonist, and metiamide, a selective histamine H2-receptor antagonist, have been determined on the cardiovascular response to intravenous infusions of a large dose of histamine, 1 X 10(-7) mol/kg/min.
B M, Johnston, D A, Owen
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Evidence that tamoxifen is a histamine antagonist
Biochemical and Biophysical Research Communications, 1985Recently we reported that both the triphenylethylene antiestrogen tamoxifen, and the novel compound N,N-diethyl-2-[(4 phenylmethyl)-phenoxy]-ethanamine. HCl (DPPE), which is selective for the antiestrogen binding site, may be histamine antagonists and have suggested that the antiestrogen binding site may be a growth-promoting histamine receptor ...
E A, Kroeger, L J, Brandes
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Histamine and its antagonists in asthma
Journal of Allergy and Clinical Immunology, 1989Histamine has been recognized as a potent effector agent in allergic responses for many years. Windaus and Vogt’ first synthesized histamine in 1907, but it was Dale and Laidlaw who originally suggested that this substance could be liberated during an anaphylactic reaction when they observed that the features of anaphylaxis could be reproduced by the ...
P, Rafferty, S T, Holgate
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Histamine and Histamine Antagonists
1991Together with the two previous volumes of the "Handbook of Experimental Pharmacology" on histamine and antihistamines (volume 18, part 1, 1966 and part 2, 1978), the present volume yields a picture of a still rapidly developing field of research. It covers the process in histamine research during the past two decades. As a result of a consensus meeting
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The evaluation of histamine antagonists in man
European Journal of Clinical Pharmacology, 1971A new method for evaluating histamine antagonists in man is described based on diminution of the effects of intradermal histamine. The inter and intra subject variability of such effects is examined experimentally and previous descriptions reviewed. Measures are adopted to minimise the effects and so achieve maximum economy of drug administrations and ...
A S, Fowle, D T, Hughes, G J, Knight
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Effects of histamine and histamine antagonists on intestinal capillary permeability
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1981Steady-state lymph flow, blood flow, and lymph and plasma total protein concentration were measured in an autoperfused cat ileum preparation during the continuous infusion of histamine at venous pressures of 0, 10, 20, and 30 mmHg. The capillary osmotic reflection coefficients for total proteins and each protein fraction were estimated.
N A, Mortillaro +4 more
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Histamine, Histamine Antagonists and Cromones
1989Histamine was discovered independently from two sources in the first decade of this century by KUTSCHER (1910) and by WINDAUS and VOGT (1907). WINDAUS and VOGT prepared histamine synthetically by the decarboxylation of histidine whereas Kutscher identified histamine as a base in ergot.
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Histamine H2-receptor antagonists
Baillière's Clinical Gastroenterology, 1988The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine H2-Receptor Antagonists
Nursing Clinics of North America, 1991In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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