Results 201 to 210 of about 167,267 (301)

Recent progress in postoperative nausea and vomiting after thyroidectomy. [PDF]

Front Surg
Zhao Q, Song F, Cui M, Jia H, Fu R, Wu G, Zhou D.   +6 more
europepmc   +1 more source

Trafficking and potentiation of Nav1.7 and Nav1.8 channels are mediated by IQGAP1

The Journal of Physiology, EarlyView.
Abstract figure legend IQGAP1 binds to the voltage‐gated Nav1.7 and Nav1.8 channels and TRPA1 channels in sensory neurons. Inflammatory mediators (IM), including PGE2 and TNFα, released during nerve injury and inflammation activate intracellular signalling messengers such as PKA, p38 MAPK and Cdc42 through their respective receptors.
Xuming Zhang, Pabitra Hriday Patra, Jinquan Yang   +2 more
wiley   +1 more source

MRGPRX2 as a novel therapeutic target in headache. [PDF]

Neurotherapeutics
Nematgorgani S, Brandon JM, Dussor G.
europepmc   +1 more source

Risk Stratification for Rebleeding in Obscure Gastrointestinal Bleeding After Comprehensive Gastrointestinal Evaluation

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aim: Obscure gastrointestinal bleeding (OGIB) is defined as bleeding of unknown origin after comprehensive upper, lower, and small‐bowel evaluations. However, the incidence and predictors of rebleeding after negative comprehensive gastrointestinal evaluation remain unclear.
Sachiyo Onishi, Kiichi Otani, Naoya Masuda, Hiroki Taniguchi, Kentaro Kojima, Jun Takada, Masaya Kubota, Takashi Ibuka, Masahito Shimizu   +8 more
wiley   +1 more source

Histamine and Skin Barrier: Are Histamine Antagonists Useful for the Prevention or Treatment of Atopic Dermatitis?

J Clin Med, 2015
De Benedetto A, Yoshida T, Fridy S, Park JE, Kuo IH, Beck LA.   +5 more
europepmc   +1 more source

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley   +1 more source

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis. [PDF]

J Med Chem
Weber P, Smits R, Lim HD, Andaloussi M, Wijkmans J, de Boer B, Tran TD, Zarzycka B, Dekker ME, van der Meer T, Riemens R, Hauwert N, Wagner G, Vischer HF, Chapin MJ, Gomes P, Whitlock A, Wijtmans M, Leurs R, de Esch IJP.   +19 more
europepmc   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Identification of novel peripherally restricted risperidone-like dopamine D2 receptor antagonists for prolactin-mediated neuroprotection through a multi-stage in silico screening. [PDF]

PLoS One
Kim S, Jo WH, Cha JO, Kim MS.
europepmc   +1 more source

The Mycorrhizal Fungal Species Funneliformis mosseae Reshapes Rhizosphere Microbial Metabolic Pathways of Soybeans Under Tetracycline Stress

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The presence of residual antibiotics (tetracycline) poses a threat to food safety in the black soils of northeastern China and a mycorrhizal fungal species Funneliformis mosseae could mitigate the negative effects. This study tracked the changes in soybeans' rhizospheric microbial profiles and the associated metabolites during the bioremediation ...
Chao Yang, Baiyan Cai, Harry Lye Hin Chong, Juan Li, Linghui Li, Jean Wan Hong Yong, Khim Phin Chong   +6 more
wiley   +1 more source