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Histamine, Histamine Antagonists and Cromones
1989Histamine was discovered independently from two sources in the first decade of this century by KUTSCHER (1910) and by WINDAUS and VOGT (1907). WINDAUS and VOGT prepared histamine synthetically by the decarboxylation of histidine whereas Kutscher identified histamine as a base in ergot.
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Histamine H2-receptor antagonists
Baillière's Clinical Gastroenterology, 1988The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine H2-Receptor Antagonists
Nursing Clinics of North America, 1991In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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Histamine and Histamine Antagonists
2017Matthew R. Cooke, Joseph A. Giovannitti
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Revue medicale de Bruxelles, 2003
Histamine is an important mediator for early phase allergic reactions that are involved in atopic diseases, mediated by specific IgE antibodies. After allergenic contact, its liberation induces unpleasant symptoms like itching, several manifestations as local vasodilatation, bronchoconstriction, mucus hypersecretion.
J, Duchateau, M, Heenen, J, Sternon
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Histamine is an important mediator for early phase allergic reactions that are involved in atopic diseases, mediated by specific IgE antibodies. After allergenic contact, its liberation induces unpleasant symptoms like itching, several manifestations as local vasodilatation, bronchoconstriction, mucus hypersecretion.
J, Duchateau, M, Heenen, J, Sternon
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