Results 291 to 300 of about 53,301 (333)

Histamine, histamine antagonists and regional blood flow

European Journal of Pharmacology, 1977
The effects of mepyramine, a selective histamine H1-receptor antagonist, and metiamide, a selective histamine H2-receptor antagonist, have been determined on the cardiovascular response to intravenous infusions of a large dose of histamine, 1 X 10(-7) mol/kg/min.
B M, Johnston, D A, Owen
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Histamine and Histamine Antagonists

1991
Together with the two previous volumes of the "Handbook of Experimental Pharmacology" on histamine and antihistamines (volume 18, part 1, 1966 and part 2, 1978), the present volume yields a picture of a still rapidly developing field of research. It covers the process in histamine research during the past two decades. As a result of a consensus meeting
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Histamine Agonists and Antagonists

Acta Oto-Laryngologica, 1991
The role of histamine in brain function is discussed. A brief review is presented on the three types of histamine receptors with regard to their biochemistry and functions. The agonists and antagonists of these three classes of histamine receptors are discussed, together with the role such compounds play in clinical therapy and pharmacology.
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Histamine H2-receptor antagonists

Baillière's Clinical Gastroenterology, 1988
The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine and Histamine Receptor Antagonists in Cancer Biology

Inflammation & Allergy - Drug Targets, 2010
Histamine has been demonstrated to be involved in cell proliferation, embryonic development, and tumour growth. These various biological effects are mediated through the activation of specific histamine receptors (H1, H2, H3, and H4) that differ in their tissue expression patterns and functions.
Bruno, Blaya, Francesca, Nicolau-Galmés, Shawkat M, Jangi, Idoia, Ortega-Martínez, Erika, Alonso-Tejerina, Juan, Burgos-Bretones, Gorka, Pérez-Yarza, Aintzane, Asumendi, María D, Boyano   +8 more
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Histamine H2-Receptor Antagonists

Nursing Clinics of North America, 1991
In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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2-Aryloxymethylmorpholine histamine H3 antagonists

Bioorganic & Medicinal Chemistry Letters, 2008
The synthesis and biological activity of a new series of 2-aryloxymethylmorpholine histamine H(3) antagonists is described. The new compounds are high affinity histamine H(3) ligands that penetrate the CNS and occupy the histamine H(3) receptor in rat brain.
Michael A, Letavic, John M, Keith, Kiev S, Ly, Pascal, Bonaventure, Mark A, Feinstein, Brian, Lord, Kirsten L, Miller, S Timothy, Motley, Diane, Nepomuceno, Steven W, Sutton, Nicholas I, Carruthers   +10 more
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Histamine H-2 Receptor Antagonists

Annals of Internal Medicine, 1977
Excerpt The actions of histamine are mediated by two types of receptors that are present on a number of morphologically distinct cell types (1).
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Histamine, Histamine Antagonists and Cromones

1989
Histamine was discovered independently from two sources in the first decade of this century by KUTSCHER (1910) and by WINDAUS and VOGT (1907). WINDAUS and VOGT prepared histamine synthetically by the decarboxylation of histidine whereas Kutscher identified histamine as a base in ergot.
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[H1 histamine antagonists].

Revue medicale de Bruxelles, 2003
Histamine is an important mediator for early phase allergic reactions that are involved in atopic diseases, mediated by specific IgE antibodies. After allergenic contact, its liberation induces unpleasant symptoms like itching, several manifestations as local vasodilatation, bronchoconstriction, mucus hypersecretion.
J, Duchateau, M, Heenen, J, Sternon
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