Results 111 to 120 of about 8,121 (227)

Evidence for both histamine H1 and H2 receptors on human articular chondrocytes

, 1987
SUMMARY Using specific histamine HI and H2 receptor antagonists, evidence is presented for the existence of both H1 and H2 receptors on human articular chondrocytes in vitro.
D J Taylor, D E Woolley
core  

Differential photoaffinity labelling of serotonin-S2 receptors and histamine-H1 receptors using 7-azidoketanserin

, 1985
7-Azidoketanserin, a potent photoaffinity probe for serotonin-S2 receptors was shown to irreversibly photoinactivate histamine-H1receptors as well. The photolabelling of H1-receptors could be prevented by several selective histamine-H1 antagonists.
Pierre M. Laduron, Wouters, Walter, Walter Wouters, Jacky Van Dun, Van Dun, Jacky, Laduron, Pierre M., Leysen, Josée E., Josée E. Leysen   +7 more
core   +1 more source

Compound 48/80, a histamine-depleting agent, blocks the protective effect of morphine against electroconvulsive shock in mice

Brazilian Journal of Medical and Biological Research, 2000
We have shown that morphine has an anticonvulsive effect against maximal electroconvulsive shock (MES) in mice, and this effect is antagonized by histamine H1-receptor antagonists.
Karadag C.H., Dokmeci D., Dost T., Ulugol A., Dokmeci I.   +4 more
doaj  

Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects

World Allergy Organization Journal
Background: Androgenetic alopecia (AGA), though traditionally attributed to androgens and genetics, is increasingly linked to immune and inflammatory pathways.
Han-Wei Zhang, MD, PhD, Ya-Ting Chang, MD, PhD, Yi-Jie Kuo, MD, PhD, Yu-Pin Chen, MD, PhD, Yu-Shan Lin, BS, Fuu-Jen Tsai, PhD   +5 more
doaj   +1 more source

Role and immunomodulatory profile of histamine receptors by H1 and H2 antagonists

, 2008
The present study was designed to delineate the immunomodulatory role of histamine receptors (H1- and H2-) on induction of antibody response to sheep red blood cells (SRBC), as well as the antibody generation profile, in rabbit system, systemically.
Mohd. Shahid, Trivendra Tripathi, Rahat Khan, Mashiatullah Siddiqui   +3 more
core  

Effect of histamine‐receptor antagonism on the circulating inflammatory cell and cytokine response to exercise: A pilot study

Physiological Reports
The purpose of this study was to gain insight into histamine's role in the exercise inflammatory response and recovery from exercise. To explore this, young healthy participants (n = 12) performed 300 eccentric leg extensions under control (Placebo ...
Matthew R. Ely, Joshua E. Mangum, Karen Wiedenfeld Needham, Christopher T. Minson, John R. Halliwill   +4 more
doaj   +1 more source

Identification of novel competitive antagonists for Histamine H1 receptor in Malaysian kelulut honey [PDF]

Current breakthroughs in molecular docking approaches have significantly contributed to discovering novel antagonists that competitively bind to histamine H1 receptor (H1R), thereby inhibiting histamine-mediated reactions.
Feng, Tan wei, Dong, RuiHai, Raihana Zahirah, Edros   +2 more
core  

H1 histamine receptor mediates inflammatory responses in human keratinocytes.

, 2004
Background: Keratinocytes participate in initiation and. amplification of T-cell-mediated skin diseases. During these disorders, histamine can be released from both residents skin cells and immigrating leukocytes, and can affect the functions of ...
Fluhr J, Giustizieri ML, GIROLOMONI, Giampiero, Albanesi C, GISONDI, Paolo, Norgauer J   +5 more
core  

Crystallographic and conformational studies on histamine H1-receptor antagonists. IV. On the stereochemical vector of antihistaminic activity

, 1986
The geometries of 14 histamine H1-receptor antagonists have been compared with the aim of finding out a common stereochemical vector of antihistaminic activity.
BERTOLASI, Valerio, BOREA, Pier Andrea, GILLI, Gastone   +2 more
core  

Moving beyond promethazine: Advancing precision in antiemetic therapy. [PDF]

SAGE Open Med
Ryan MF, Lagasse C.
europepmc   +1 more source