Results 11 to 20 of about 251,504 (224)
Histamine H1 antagonists and clinical characteristics of febrile seizures [PDF]
International Journal of General Medicine, 2012 Mohammed A ZolalyDepartment of Pediatrics, College of Medicine, Taibah University, Al-Madinah Al-Munawarah, Kingdom of Saudi ArabiaBackground: The purpose of this study was to determine whether seizure susceptibility due to antihistamines is provoked in ...
Zolaly MA
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LifeHistamine receptor antagonists, which can bind to specific histamine receptors on target cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated disorders.
Erwen Kou, Yuanjie Zhu
exaly +4 more sources
Journal of Pharmacological Sciences, 2008 We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma +4 more
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The Impact of H1–H4 Receptor Antagonists on the Levels of Selected Oxidative Stress Markers in Liver and Muscle Tissue in an Animal Model of Colitis [PDF]
PharmaceuticalsBackground/Objectives: The global prevalence and incidence of inflammatory bowel diseases have risen in the past two decades. Among them, Crohn’s disease and ulcerative colitis are still challenging to treat due to vascular and proliferative alterations.
Bartosz Bogielski +16 more
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Antidiabetic Properties of Histamine H1 Receptor Antagonists: A Systematic Review [PDF]
AntioxidantsAllergies and diabetes mellitus are highly prevalent, frequently co-occurring diseases. Antihistamines, the first-line treatment for allergies, block H1 receptors but also exhibit anti-inflammatory and antioxidant properties that may improve glucose ...
Michał Radzikowski, Mateusz Maciejczyk
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Journal of Pharmacological Sciences, 2007 Histamine is a major mediator in allergy acting mainly through the histamine H1 receptor (H1R). Although H1R up-regulation has been suggested as an important step for induction of allergic symptoms, little is known about the regulation of H1R level. Here
Asish K. Das +10 more
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Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation. [PDF]
PLoS ONE, 2014 BACKGROUND: Histamine drives pruritus in allergic skin diseases which clinically constitutes a most disruptive symptom. Skin pathology in allergic skin diseases is crucially influenced by different T-helper subsets. However, the contribution of different
Subhashree Mahapatra +10 more
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Improved survival in several cancers with use of H1-antihistamines desloratadine and loratadine
Translational Oncology, 2021 Background: We have previously shown an association with substantially improved survival in breast cancer and melanoma for desloratadine and loratadine users, and set out to find whether an improved survival can be seen in tumors with and without a known
Ildikó Fritz +2 more
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Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil [PDF]
Anais Brasileiros de Dermatologia, 2018 : Background: Several dermatoses are mediated by histamine, such as urticaria, angioedema, and papular urticaria. There are no Brazilian studies comparing the potency of antihistamines.
Helena Maciel-Guerra +6 more
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Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells
Scientific Reports, 2021 Cancer therapy is often hampered by the disease’s development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is ...
Nobuki Matsumoto +5 more
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