Results 11 to 20 of about 267,254 (237)
Histamine antagonists promote cancer immunosurveillance
OncoImmunology, 2023 Recently, a cellular mini-immune system comprising infinitely expandable dendritic cells and T cells led to the discovery that histamine receptor H1 antagonists act on T cells to stimulate their proliferation and polarization toward a Th1/Tc1 phenotype ...
Peng Liu, Guido Kroemer, Oliver Kepp
doaj +2 more sources
Effects of H1–receptor antagonists in antidepressant tests in rats [PDF]
Al Ameen Journal of Medical Sciences, 2008 : Considering the vast data suggesting the role of brain histamine(HA) in behaviour,emotions,anxiety and depression;four H1-receptor antagonists; promethazine, diphenhydramine, cyclizine and pheniramine were subjected to antidepressant tests in rats ...
Chitra C.Khanwelkar
doaj +1 more source
Journal of Pharmacological Sciences, 2007 Histamine is a major mediator in allergy acting mainly through the histamine H1 receptor (H1R). Although H1R up-regulation has been suggested as an important step for induction of allergic symptoms, little is known about the regulation of H1R level. Here
Asish K. Das +10 more
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Could histamine h1 receptor antagonists be used for treating covid-19? [PDF]
, 2021 COVID-19 has rapidly become a pandemic worldwide, causing extensive and long-term health issues. There is an urgent need to identify therapies that limit SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Unbalanced lung inflammation is a
Changbo Qu +7 more
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Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials [PDF]
, 1982 To demonstrate the efficacy of a premedication with H1- + H2-receptor antagonists against histamine-release responses in anaesthesia and surgery 3 randomized controlled trials were conducted in patients, volunteers and experimental animals (dogs ...
Lorenz, Wilfried +5 more
core +1 more source
Perioperative uses of histamine antagonists [PDF]
, 1990 Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening ...
Lorenz, Wilfried +3 more
core +1 more source
Journal of Pharmacological Sciences, 2005 The second-generation histamine-H1-receptor antagonists, such as epinastine and cetirizine, are used as non-sedating antihistamines for treating allergic symptoms due to their poor ability to penetrate blood-brain barrier.
Junzo Kamei +4 more
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Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia [PDF]
, 1994 Although histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant cardiorespiratory disturbances serious enough to warrant prophylaxis with antihistamines.
Lorenz, Wilfried +10 more
core +1 more source
No effects on sleep of a histamine H1‐receptor antagonist: temelastine. [PDF]
British Journal of Clinical Pharmacology, 1986 Twelve volunteer poor sleepers of mean age 57 years took placebo on each of 3 consecutive nights, and temelastine 100 mg on 3 consecutive nights in a double‐blind balanced order study. Sleep in the EEG laboratory was unaffected by the drug.
K, Adam, I, Oswald
openaire +2 more sources
Are hypotension and rash after atracurium really caused by histamine release? [PDF]
, 1994 A prospective, randomized, double-blind study was performed in 40 patients (ASA class I-III) treated with atracurium to ascertain whether histamine release caused hemodynamic or cutaneous changes.
Doenicke, A. +4 more
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