Results 31 to 40 of about 267,254 (237)

The relation between antihistamine medication during early pregnancy & birth defects

open access: yesEgyptian Journal of Medical Human Genetics, 2015
Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H1 or H2). H1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.
Rabah M. Shawky, Neveen S. Seifeldin
doaj   +1 more source

Determination of histamine in human plasma: the European external quality control study 1988 [PDF]

open access: yes, 1990
There is an increasing interest in measuring human plasma histamine levels in various clinical conditions. A variety of 'old' and newly developed techniques are applied to meet this demand.
Lorenz, Wilfried   +7 more
core   +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

open access: yesMediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask   +6 more
wiley   +1 more source

Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H1 Receptor Blockade

open access: yesFrontiers in Psychiatry, 2012
Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics.
Kjell A Svensson
doaj   +1 more source

Cetirizine a histamine H1 receptor antagonist improves viral myocarditis [PDF]

open access: yesJournal of Inflammation, 2010
We showed that mast cells played a critical role in the progression of heart failure induced by pressure overload and viral myocarditis in mice. In this study, we investigated the effect of cetirizine, a selective H1 receptor antagonist, on experimental viral myocarditis induced by encephalomyocarditis (EMC) virus.Four-week-old inbred male DBA/2 mice ...
Yamamoto Kanjo   +2 more
openaire   +3 more sources

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Effect of histamine H1 receptor antagonists on antigen-induced increase of cough sensitivity in guinea pigs [PDF]

open access: yes, 2000
Eosinophilic airway inflammation and increased cough sensitivity without bronchial hyperresponsiveness are the pathologic and physiologic features of bronchodilator-resistant non-productive cough-associated global atopic tendency, abbreviated herein as ...
Liu, Qi
core   +1 more source

In Vivo Anti-Inflammatory Effect of H1 Antihistamines in Allergic Rhinitis: A Randomized Clinical Trial

open access: yesBalkan Medical Journal, 2015
Background: Allergic rhinitis is characterized by a chronic inflammation of nasal mucosa and represents a risk factor for asthma occurrence. H1 antihistamines reduce the symptoms of rhinitis, but some compounds may have anti-inflammatory properties ...
Corina I. Bocşan   +5 more
doaj   +1 more source

Antihistamines in the treatment of allergic diseases: not as simple as it seems!

open access: yesКлинический разбор в общей медицине, 2023
According to WHO, up to 35% of the world's population suffers from allergic diseases, and this number is growing exponentially. Histamine has been proven to play a key physiological role in the pathogenesis of allergic disorders by affecting tissues ...
Igor S. Guschin   +2 more
doaj   +1 more source

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