Results 21 to 30 of about 7,478 (186)
The relation between antihistamine medication during early pregnancy & birth defects
Egyptian Journal of Medical Human Genetics, 2015 Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H1 or H2). H1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.
Rabah M. Shawky, Neveen S. Seifeldin
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Allergic Rhinoconjunctivitis: the Role of Histamine
Mediators of Inflammation, 1994 Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
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Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
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Frontiers in Psychiatry, 2012 Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics.
Kjell A Svensson
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British Journal of Clinical Pharmacology, EarlyView.Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask +6 more
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Balkan Medical Journal, 2015 Background: Allergic rhinitis is characterized by a chronic inflammation of nasal mucosa and represents a risk factor for asthma occurrence. H1 antihistamines reduce the symptoms of rhinitis, but some compounds may have anti-inflammatory properties ...
Corina I. Bocşan +5 more
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Antihistamines in the treatment of allergic diseases: not as simple as it seems!
Клинический разбор в общей медицине, 2023 According to WHO, up to 35% of the world's population suffers from allergic diseases, and this number is growing exponentially. Histamine has been proven to play a key physiological role in the pathogenesis of allergic disorders by affecting tissues ...
Igor S. Guschin +2 more
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Pharmacological study of ebastine, a novel histamine H1-receptor antagonist.
Folia Pharmacologica Japonica, 1994 The anti-allergic activity of ebastine, a novel antihistamine, was assessed in comparison with several antihistamines. 1) Orally administered ebastine dose-dependently inhibited 7-day homologous passive cutaneous anaphylaxis (PCA), experimental allergic rhinitis and experimental asthma in guinea pigs or rats (ED50-values were 2.17, 0.29 and 0.35 mg/kg,
YAKUO, Ikuhisa +6 more
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Cetirizine a histamine H1 receptor antagonist improves viral myocarditis [PDF]
Journal of Inflammation, 2010 We showed that mast cells played a critical role in the progression of heart failure induced by pressure overload and viral myocarditis in mice. In this study, we investigated the effect of cetirizine, a selective H1 receptor antagonist, on experimental viral myocarditis induced by encephalomyocarditis (EMC) virus.Four-week-old inbred male DBA/2 mice ...
Yamamoto Kanjo +2 more
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Epilepsia, EarlyView.Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer +7 more
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