Results 21 to 30 of about 251,504 (224)

The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions

Frontiers in Pharmacology, 2021
This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann, Uwe Kirchhefer, Stefan Dhein, Britt Hofmann, Ulrich Gergs   +4 more
doaj   +1 more source

Could histamine h1 receptor antagonists be used for treating covid-19? [PDF]

, 2021
COVID-19 has rapidly become a pandemic worldwide, causing extensive and long-term health issues. There is an urgent need to identify therapies that limit SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Unbalanced lung inflammation is a
Changbo Qu, Qu, Changbo, Pan, Yihang, Gwenny Fuhler, Fuhler, Gwenny M., C Qu, G.M. (Gwenny) Fuhler, Yihang Pan   +7 more
core   +1 more source

Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials [PDF]

, 1982
To demonstrate the efficacy of a premedication with H1- + H2-receptor antagonists against histamine-release responses in anaesthesia and surgery 3 randomized controlled trials were conducted in patients, volunteers and experimental animals (dogs ...
Lorenz, Wilfried, Doenicke, A., Schöning, B., A. Doenicke, W. Lorenz, B. Schöning   +5 more
core   +1 more source

Perioperative uses of histamine antagonists [PDF]

, 1990
Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening ...
Lorenz, Wilfried, Doenicke, A., Ennis, M., Dick, W., Wolfgang Dick, Madeleine Ennis, Wilfried Lorenz, Alfred Doenicke   +7 more
core   +1 more source

Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia [PDF]

, 1994
Although histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant cardiorespiratory disturbances serious enough to warrant prophylaxis with antihistamines.
Lorenz, Wilfried, Doenicke, A., Weber, Doris, Junginger, T., Stinner, B., Duda, D., Black, A., Menke, H., Trial Group, Mainz/Marburg, Sitter, H., Dick, W.   +10 more
core   +1 more source

Are hypotension and rash after atracurium really caused by histamine release? [PDF]

, 1994
A prospective, randomized, double-blind study was performed in 40 patients (ASA class I-III) treated with atracurium to ascertain whether histamine release caused hemodynamic or cutaneous changes.
Doenicke, A., Lorenz, Wilfried, Hoernecke, R., Gottardis, M., Moss, J.   +4 more
core   +1 more source

Perioperative nonspecific histamine release: a new classification by aetiological mechanisms and evaluation of their clinical relevance [PDF]

, 1993
As a consequence of the performance of a randomized controlled clinical trial on perioperative histamine release and cardiovascular and respiratory disturbances, several types of increases in plasma histamine had to be distinguished instead of only two ...
Lorenz, Wilfried, Schäfer, U., Junginger, T., Stinner, B., Nies, C., Duda, D., Hasse, C., Menke, H., Rothmund, M., Sitter, H.   +9 more
core   +1 more source

Histamine receptors in GtoPdb v.2021.3 [PDF]

, 2021
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Levi, Roberto, Leurs, Rob, Cowart, Marlon, Hill, Stephen J., Young, J. Michael, Gutzmer, Ralf, Seifert, Roland, Ganellin, C. Robin, Shankley, Nigel P., Timmerman, Henk, Haas, Helmut L., Stark, Holger, Panula, Pertti, Schunack, Walter, Chazot, Paul, Fukui, Hiroyuki, Liu, Steve, Schwartz, Jean-Charles, Hills, Rebecca, Thurmond, Robin, Steve Liu, Jean-Charles Schwartz, Holger Stark, Nigel P. Shankley, Robin Thurmond, Paul Chazot, Stephen J. Hill, J. Michael Young, Marlon Cowart, Rebecca Hills, C. Robin Ganellin, Rob Leurs, Roberto Levi, Hiroyuki Fukui, Roland Seifert, Walter Schunack, Henk Timmerman, Pertti Panula, Helmut L. Haas, Ralf Gutzmer   +39 more
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Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors [PDF]

, 2019
The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions.
Stromberga, Zane, Chess-Williams, Russ, Moro, Christian; id_orcid   +2 more
core   +1 more source

Histamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Hill, Stephen J., Young, J. Michael, Steve Liu, Jean-Charles Schwartz, Shankley, Nigel P., Haas, Helmut L., Holger Stark, Nigel P. Shankley, Robin Thurmond, Paul Chazot, Stephen J. Hill, Fukui, Hiroyuki, Hills, Rebecca, J. Michael Young, Levi, Roberto, Leurs, Rob, Marlon Cowart, Rebecca Hills, Cowart, Marlon, Gutzmer, Ralf, C. Robin Ganellin, Seifert, Roland, Ganellin, C. Robin, Rob Leurs, Roberto Levi, Timmerman, Henk, Stark, Holger, Panula, Pertti, Hiroyuki Fukui, Schunack, Walter, Chazot, Paul, Roland Seifert, Liu, Steve, Schwartz, Jean-Charles, Walter Schunack, Henk Timmerman, Pertti Panula, Helmut L. Haas, Thurmond, Robin, Ralf Gutzmer   +39 more
core   +1 more source