Results 101 to 110 of about 39,913 (287)

Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2–/– mice and human cholangiocarcinoma tumorigenesis

Hepatology, 2018
Primary sclerosing cholangitis (PSC) patients are at risk of developing cholangiocarcinoma (CCA). We have shown that (1) histamine increases biliary hyperplasia through H1/H2 histamine receptors (HRs) and (2) histamine levels increase and mast cells (MCs)
Lindsey Kennedy, Laura A Hargrove, Jennifer Demieville, W. Karstens, Hannah Jones, S. DeMorrow, F. Meng, P. Invernizzi, F. Bernuzzi, G. Alpini, Steven A. Smith, Austin Akers, Vik Meadows, H. Francis   +13 more
semanticscholar   +1 more source

Occurrence and effects of pharmaceutical chemicals in Chicago metropolitan area streams [PDF]

, 2006
U.S. Department of the InteriorU.S.
Rosi-Marshall, Emma
core  

Histamine and migraine revisited: mechanisms and possible drug targets

The Journal of Headache and Pain, 2019
Objective To review the existing literature on histamine and migraine with a focus on the molecule, its receptors, its use in inducing migraine, and antihistamines in the treatment of migraine. Background Histamine has been known to cause a vascular type
Jacob Worm, Katrine Falkenberg, Jes Olesen   +2 more
doaj   +1 more source

H3 antagonists and postoperative cognitive dysfunction

Journal of Anaesthesiology Clinical Pharmacology, 2019
Since histamine (HA) was first synthesized in 1907 and isolated as a bacterial contaminant of an extract of ergot in 1910, its role in health and disease and its molecular mechanism of action have been unraveled, leading to the formulation of an array of
Chandrasekhar Krishnamurti
doaj   +1 more source

Protective effects of exogenous and endogenous hydrogen sulfide in mast cell-mediated pruritus and cutaneous acute inflammation in mice. [PDF]

, 2016
Published onlineJournal ArticleThis is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.The recently described 'gasomediator' hydrogen sulfide (H2S) has been involved in pain mechanisms, but its ...
Cerqueira, AR, Costa, SK, De Nucci, G, Ekundi-Valentim, E, Florenzano, J, Muscará, MN, Ribela, MT, Rodrigues, L, Santos, KT, Schmidt, TP, Soares, AG, Teixeira, SA, Whiteman, M, Wood, M   +13 more
core   +1 more source

Effect of histamine‐receptor antagonism on the circulating inflammatory cell and cytokine response to exercise: A pilot study

Physiological Reports
The purpose of this study was to gain insight into histamine's role in the exercise inflammatory response and recovery from exercise. To explore this, young healthy participants (n = 12) performed 300 eccentric leg extensions under control (Placebo ...
Matthew R. Ely, Joshua E. Mangum, Karen Wiedenfeld Needham, Christopher T. Minson, John R. Halliwill   +4 more
doaj   +1 more source

ROLE OF HISTAMINE IN GASTRIC SECRETION: FROM DISCOVERY TO CLINICAL APPLICATION (A Tribute Leon Popielski To 150-Anniversary From His Birth)

Праці Наукового товариства імені Шевченка. Медичні науки, 2019
Professor of Lviv National Medical University (formerly known as Jan Kazimierz Lemberg University), Ukraine, Leon Popielski was the fi rst to recognize that histamine stimulated gastric acid secretion 100 years ago, at 1916.
Oksana Zayachkivska, Anna Musiol, Iryna Muzyka   +2 more
doaj   +1 more source

Chemical Genetic Identification of the Histamine H1 Receptor as a Stimulator of Insulin-Induced Adipogenesis [PDF]

, 2004
A large collection of bioactive compounds with diverse biological effects can be used as probes to elucidate new biological mechanisms that influence a particular cellular process.
Yoshinori Kawazoe, Satoshi Tanaka, Motonari Uesugi, Green, Green, Rosen, MacDougald, Zhang, Dowell, Font de Mora, Engelman, Ho, Ohtsu, Hill, Hill, Nakamura, Hiroi, Elbashir, Brummelkamp, Beaven, Beaven, White, Barocelli, Schwartz, Simons, Huang, Masaki, Morimoto, Fulop, Laurier, Ishikawa, Choi, Schreiber, Stockwell, Peterson, Crews, Root, Schreiber, Kuruvilla, Ohmori, Shore   +40 more
core   +3 more sources

Antacid preparations in the modern treatment of acid-base disorders

Медицинский совет, 2014
Until the middle of the XX century, a large group of drugs called antacids played the key role in the treatment of acid-related diseases. Antacids have long been used to relieve heartburn and pain in the upper gastrointestinal tract.
S. A. Babanov, E. B. Grischenko
doaj   +1 more source

Histamine H1 and H2 Receptor Antagonists Accelerate Skin Barrier Repair and Prevent Epidermal Hyperplasia Induced by Barrier Disruption in a Dry Environment [PDF]

, 2001
Yutaka Ashida, Mitsuhiro Denda, Tetsuji Hirao   +2 more
openalex   +1 more source