Results 181 to 190 of about 9,091 (225)
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Localization of histamine and histamine H2-receptor antagonists in the gastric mucosa
The Histochemical Journal, 1977Histamine stimulates acid secretion by the parietal cell and this secretion is inhibited by the histamine H2-receptor antagonists. Whole body autoradiography showed that radioactivity from 14C-histamine was localized in the artery walls of the stomach and in the muscularis mucosae, but that the level in the fundic mucosa was the same as the blood. When
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Structural Requirements for Histamine H2 Agonists and H2 Antagonists
1991This chapter reviews the structural requirements for H2 agonists and antagonists. Section B discusses the agonists, which are divided into three classes: the non-selective histamine analogues, showing H2 activity as well as H1 and H3 activity; dimaprit, a selective, but moderately active agonist which allows no substitution without a dramatic fall in ...
H. van der Goot, A. Bast, H. Timmerman
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The pharmacology of histamine H2-receptor antagonists.
Methods and findings in experimental and clinical pharmacology, 1989The structure of the first histamine H2-receptor antagonist, burimamide was described in 1972. Since then, numerous compounds with diverse chemical structures have been shown to possess H2-receptor antagonist activity. Most of these compounds comprise an aromatic ring and polar group linked by a flexible chemical chain.
J G, Mills, J R, Wood
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Histamine and histamine H1- and H2-receptor antagonists in acute inflammation
Biochemical Society Transactions, 1980D A, Owen, D F, Woodward
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Histamine H2 Receptor-Antagonists
JAMA: The Journal of the American Medical Association, 1976openaire +3 more sources
Histamine H2 Receptor Antagonists and the Cardiovascular System
Pharmacological Research, 1993G, Bertaccini, E, Poli, G, Coruzzi
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Histamine H2 antagonists and the nervous system.
American family physician, 1986In extensive clinical trials, both cimetidine and ranitidine appeared free of central nervous system side effects. The potential for neurologic complications became apparent only after these drugs had been subjected to the test of general use. The incidence of side effects is generally low, but in the elderly and in patients with renal or hepatic ...
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Behavioural effects of histamine and its antagonists: a review
Psychopharmacology, 1988Jason M White
exaly