Results 181 to 190 of about 42,892 (256)
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Structural Requirements for Histamine H2 Agonists and H2 Antagonists
1991This chapter reviews the structural requirements for H2 agonists and antagonists. Section B discusses the agonists, which are divided into three classes: the non-selective histamine analogues, showing H2 activity as well as H1 and H3 activity; dimaprit, a selective, but moderately active agonist which allows no substitution without a dramatic fall in ...
H. van der Goot, A. Bast, H. Timmerman
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Recent developments in histamine H2-antagonists
Trends in Pharmacological Sciences, 1981R.T. Brittain, D. Jack, B.J. Price
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Histamine receptors, agonists, and antagonists in health and disease.
Handbook of Clinical Neurology, 2021Histamine in the brain is produced by a group of tuberomamillary neurons in the posterior hypothalamus and a limited number of mast cells in different parts of the brain. Four G-protein-coupled receptors mediate the effects of histamine.
P. Panula
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Water Research, 2020
Peroxymonosulfate (PMS) is an appealing oxidant for organic contaminant destruction relying on radical generation after activation. Herein, we report PMS-promoted rapid degradation of histamine H2-receptor antagonists (HRAs) through non-radical process ...
Yajie Qian +8 more
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Peroxymonosulfate (PMS) is an appealing oxidant for organic contaminant destruction relying on radical generation after activation. Herein, we report PMS-promoted rapid degradation of histamine H2-receptor antagonists (HRAs) through non-radical process ...
Yajie Qian +8 more
semanticscholar +1 more source
Histamine H2-receptor antagonists
Baillière's Clinical Gastroenterology, 1988The first histamine H2-receptor antagonists were developed in the early 1970s, and they have a dominant role in today's management of peptic ulceration. The original regimens using either cimetidine or ranitidine attempted to control acidity across the 24 hours, but more 'modern' regimens use a large single dose of the H2-blocker in the evening, which ...
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Histamine H2-Receptor Antagonists
Nursing Clinics of North America, 1991In summary, histamine initiates acid secretion by stimulating the H2 subtype histamine receptor on parietal cells. Cimetidine, rantidine, famotidine, and nizantidine are histamine H2-receptor antagonists that block this action of histamine, reducing gastric acid output and concentration under both basal and stimulated conditions.
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Prolactin responses to histamine H2 receptor antagonists
Acta Endocrinologica, 1980Abstract. We have compared the effects of cimetidine and SK&F 92994, a new more potent histamine H2 receptor antagonist, on serum prolactin, and also assessed the effect of the H2 receptor agonist impromidine on the response to cimetidine. As previously reported, cimetidine 200 mg given as an iv bolus dose produced a marked rise in serum prolactin,
P C, Sharpe +4 more
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Inhibition of naloxone-resistant antinociception by centrally administered H2-antagonists.
Journal of Pharmacology and Experimental Therapeutics, 1989In order to test directly the hypothesis that brain histamine and H2-receptors mediate the naloxone-resistant footshock-induced antinociception (FSIA) elicited by 3 min of 3.5 mA, the effect of i.c.v.
K. Gogas, L. Hough
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Potential histamine H2-receptor antagonists. 3. Methylhistamines
Journal of Medicinal Chemistry, 1976Syntheses are described for all the mono- and some di- and trimethylhistamines. New methods are given for the known Npi, Ntau-, Nalpha-, 2-, and 4-methylhistamines and for the novel compounds, beta-methyl-, 4,Nalpha-dimethyl-, and 4,Nalpha,Nalpha-trimethylhistamines. Agonist activities are reported for stimulation of histamine H1 (guinea-pig ileum) and
G J, Durant +4 more
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