Results 51 to 60 of about 8,363 (180)

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

Food Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman, Shefali Arora, Parteek Prasher, Sukanya Chhetri, Pankaj Bhandari, William N. Setzer, Javad Sharifi‐Rad   +6 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

Stem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao, Youchao Chen, Li Cheng, Lishi Fan, Han Chen, Yushan Wan, Yi You, Yanrong Zheng, Lei Jiang, Zhong Chen, Xiangnan Zhang, Weiwei Hu   +11 more
doaj   +1 more source

Divergent Management of the Foregut Between Pulmonologists and Gastroenterologists in Advanced Cystic Fibrosis Lung Disease

Pediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Background Advanced cystic fibrosis lung disease (ACFLD) remains a major cause of morbidity, particularly in individuals requiring lung transplantation. Gastrointestinal‐related aspiration (GRASP), including reflux and motility disorders, may contribute to adverse respiratory outcomes, yet diagnostic and management strategies vary across ...
Dhiren Patel, Jeffrey King, Alexandra Wilder, Noor Al‐Hammadi, Reza Hejazi, Jodie Barkin, Christine Hachem, Christopher Vélez   +7 more
wiley   +1 more source

Six Cases of Antihistamine-Resistant Dermographic Urticaria Treated with Oral Ciclosporin

Allergology International, 2011
Background: Dermographic urticaria (DU) is characterized by strong itch and wheals induced by mechanical scratching. H1-receptor antagonists may reduce symptoms of DU to some extent, but other treatments being used for chronic spontaneous urticaria, such
Sayuri Toda, Shunsuke Takahagi, Shoji Mihara, Michihiro Hide   +3 more
doaj   +1 more source

Evidence‐Based Management Recommendations for Microfocused Ultrasound With Visualization (MFU‐V) Complications: A Multidisciplinary Consensus and Clinical Validation

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Microfocused ultrasound with visualization (MFU‐V) is a widely used noninvasive modality for skin tightening and lifting. Despite its favorable safety profile, transient and occasionally severe complications necessitate evidence‐based management protocols, which remain underdeveloped in current literature.
Valentina Dicker, Andrea Acevedo, Andrea Marcela Parra, Juan Sebastian Rodriguez Cabrales, Lina Velasquez, Carlos Bravo Rojas, Luis Alberto Parra   +6 more
wiley   +1 more source

Proton Pump Inhibitors and Gastric Cancer: A Large-Scale Propensity Score-Matched Analysis

Gut and Liver
Background/Aims : We aimed to elucidate whether proton pump inhibitor (PPI) users are at increased risk of gastric cancer compared with non-PPI users or histamine-2 receptor antagonist (H2RA) users. Methods : A population-based cohort study was conducted
Cheal Wung Huh, Nak-Hoon Son, So Hyeon Gwon, Hee Byung Koh, Hae-Ryong Yun, Da Hyun Jung   +5 more
doaj   +1 more source

Gastric ulceration in dog: A review

Veterinary World, 2013
The common acid related diseases of the upper gastrointestinal tract could be considered as primarily due to the defect in barrier function either of the gastric mucosal or duodenal epithelium leading to the formation of gastric or duodenal ulcers.
J. D. Parrah, B. A. Moulvi, Mohsin Ali Gazi, D. M. Makhdoomi, H. Athar, Shahid Dar, A. Q. Mir   +6 more
doaj   +1 more source

A Synergistic Hydrogel‐Microalgae Platform for Dual‐Targeting of Intestinal and Neuroimmune Dysfunction in Inflammatory Bowel Disease

Advanced Science, Volume 13, Issue 36, 29 June 2026.
A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu, Kangyu Jin, Bing Chen, Ruoxi Wang, Fengling Hu, Shaohua Hu, Danni Zhong, Xiaoming Li, Min Zhou   +8 more
wiley   +1 more source

Relevance of Hydrogen Bonds for the Histamine H2 Receptor-Ligand Interactions: A Lesson from Deuteration

Biomolecules, 2020
We used a combination of density functional theory (DFT) calculations and the implicit quantization of the acidic N−H and O−H bonds to assess the effect of deuteration on the binding of agonists (2-methylhistamine and 4-methylhistamine) and ...
Mojca Kržan, Jan Keuschler, Janez Mavri, Robert Vianello   +3 more
doaj   +1 more source