Results 71 to 80 of about 9,091 (225)

Rationalizing Proton Pump Inhibitor Use: Southeast Asia Consensus Recommendations

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1685-1700, June 2026.
ABSTRACT Background and Aim Proton pump inhibitors (PPIs) are integral to managing many gastrointestinal conditions. However, the prevalent inappropriate PPI prescription across Southeast Asia (SEA) is concerning. Given the absence of locally tailored recommendations to inform clinical practice, this consensus document aims to provide recommendations ...
Somchai Leelakusolvong, Tju Siang Chua, Duc Trong Quach, Andrew Ming‐Liang Ong, Ari Fahrial Syam, Augusto Jose G. Galang, Wee Kooi Cheah, Hang Viet Dao, Jose D. Sollano, Kalwinder Singh Khaira, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Sakkarin Chirapongsathorn, Yeong Yeh Lee   +13 more
wiley   +1 more source

Histamine H1 and H2 Receptor Antagonists Accelerate Skin Barrier Repair and Prevent Epidermal Hyperplasia Induced by Barrier Disruption in a Dry Environment

, 2001
Keratinocytes have histamine H1 and H2 receptors, but their functions are poorly understood. To clarify the role of histamine receptors in the epidermis, we examined the effects of histamine receptor antagonists and agonists applied epicutaneously on the
Denda, Mitsuhiro, Hirao, Tetsuji, Ashida, Yutaka   +2 more
core   +1 more source

Papel do receptor ativado por proteinases-2 (par-2) no comportamento de coçar em camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pos-Graduação em Farmacologia, Florianópolis, 2009.O objetivo do presente estudo foi investigar os possíveis mecanismos e mediadores envolvidos no
Costa, Robson da
core  

Six Cases of Antihistamine-Resistant Dermographic Urticaria Treated with Oral Ciclosporin

Allergology International, 2011
Background: Dermographic urticaria (DU) is characterized by strong itch and wheals induced by mechanical scratching. H1-receptor antagonists may reduce symptoms of DU to some extent, but other treatments being used for chronic spontaneous urticaria, such
Sayuri Toda, Shunsuke Takahagi, Shoji Mihara, Michihiro Hide   +3 more
doaj   +1 more source

Early Antibiotic Discontinuation for Children With a Positive Rapid Respiratory Viral Test Hospitalized for Suspected Bacterial Tracheostomy‐Associated Infections

Pediatric Pulmonology, Volume 61, Issue 5, May 2026.
ABSTRACT Objective Test the association between early antibiotic discontinuation and outcomes for children with a tracheostomy and positive respiratory viral PCR (RVP) hospitalized with suspected bTRAIN (bacterial TRacheostomy‐Associated INfection; pneumonia/tracheitis).
Christopher J. Russell, Naoko Kono, Margaret Rush, Andrea Hahn, Catherine S. Forster, Jonathan D. Cogen, Sarah Hofman DeYoung, John M. Morrison, Joanna Thomson, Sukhada Vaidya Mairal, Wendy J. Mack, Michael N. Neely, Tamara D. Simon, for the Pediatric Research in Inpatient Settings Network   +13 more
wiley   +1 more source

Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro [PDF]

, 1983
The in vitro effect of histamine and its antagonists, cimetidine and clemastine fumarate, on natural killer (NK) and antibody-dependent cellular Cytotoxicity (ADCC) activities of human lymphocytes was investigated.
Schwartz, Stanley A., Madhavan P.N. Nair, Nair, Madhavan P. N., Stanley A. Schwartz   +3 more
core   +1 more source

Gastric ulceration in dog: A review

Veterinary World, 2013
The common acid related diseases of the upper gastrointestinal tract could be considered as primarily due to the defect in barrier function either of the gastric mucosal or duodenal epithelium leading to the formation of gastric or duodenal ulcers.
J. D. Parrah, B. A. Moulvi, Mohsin Ali Gazi, D. M. Makhdoomi, H. Athar, Shahid Dar, A. Q. Mir   +6 more
doaj   +1 more source

Population Pharmacokinetic Modeling and Exposure‐Response Analyses of Nemtabrutinib in Patients With Hematologic Malignancies

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Nemtabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor under clinical investigation in patients with hematologic malignancies, including chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL). Nemtabrutinib plasma concentration data from 578 patients enrolled in phase 1 and 2 clinical studies, treated with doses from 5 to ...
Chiara C. Kemal, Thijs J. Zweers, Elke H. J. Krekels, Manash S. Chatterjee   +3 more
wiley   +1 more source

Relevance of Hydrogen Bonds for the Histamine H2 Receptor-Ligand Interactions: A Lesson from Deuteration

Biomolecules, 2020
We used a combination of density functional theory (DFT) calculations and the implicit quantization of the acidic N−H and O−H bonds to assess the effect of deuteration on the binding of agonists (2-methylhistamine and 4-methylhistamine) and ...
Mojca Kržan, Jan Keuschler, Janez Mavri, Robert Vianello   +3 more
doaj   +1 more source

Hydrochlorides, hydrates, hydronitrate, and an unanticipated hydrolysis product of famotidine

Acta Crystallographica Section C, Volume 82, Issue 5, Page 241-249, May 2026.
The structures of a new polymorph of famotidine hydrochloride, a famotidine hydrochloride hydrate, a new hydronitrate salt of famotidine, and an unexpected hydrolyzed complex of famotidine are reported. The famotidine hydrochloride hydrate and the hydrolyzed famotidine hydrochloride have Z′ values of 2 and 4, respectively.This article contributes to ...
MacKenzie C. Weaver, Allen G. Oliver, Toni L. O. Barstis   +2 more
wiley   +1 more source