Histamine h2 antagonists - Open Access .click

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Improvement of Fibromyalgia by Immunoglobulin/Histamine Complex Therapy for Chronic Urticaria and Allergic Rhinitis: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread musculoskeletal pain, often accompanied by fatigue, sleep disturbance, and cognitive symptoms. Although several treatment options are available, no curative therapy has been established.
Hyuk Soon Kim +3 more
wiley +1 more source

Central effects of histamine H2-receptor agonists and antagonists on nociception in the rat

, 1988
The effects of intracerebroventricular injection of histamine H2-receptor agonists (4-methylhistamine, 4-MeH; dimaprit, DIM), H2-antagonists (cimetidine, CIM; ranitidine, RAN; famotidine, FAM) and of the DIM chemical analogue SK&F 91487 on hot-plate ...
F. Guidobono +5 more
core +1 more source

New Insights Into Immunomodulatory Strategies for Drug Hypersensitivity Reactions: An EAACI Task Force Report

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are a global health concern and remain challenging to investigate owing to the heterogeneity of endotypes and phenotypes, as well as the lack of standardized biomarkers. Until recently, strict drug avoidance was the only management strategy for severe DHRs.
Ana Maria Copaescu +13 more
wiley +1 more source

Papel dos receptores histaminérgicos da medula espinhal na inflamação articular de ratos e sua possível contribuição como adjuvante para os efeitos da morfina [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA medula espinhal é conhecida por ser um centro de controle ortodrômico (nocicepção), bem como antidrômico ...
Silva, Taciane Stein da
core

Histamine analogues, XXXV: 2-substituted histamine derivatives containing classical moieties of H2-antagonists--a novel class of H1-agonists

, 1993
A new type of H1-agonists resulted from the combination of the essential histamine structure with parts of H2-antagonists. 2,4-Disubstituted imidazole derivatives were synthesized by reaction of imidic acid methyl esters with 1,3-dihydroxypropanone, 1,4 ...
Volkmar Zingel +5 more
core +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

Mediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj +1 more source

Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.
Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling. ABSTRACT pH‐dependent drug–drug interactions (DDIs) commonly occur when acid‐reducing agents (ARAs) are co‐administered with weakly basic drugs.
Yuanfang Qin +6 more
wiley +1 more source

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

Stem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao +11 more
doaj +1 more source

The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria

Allergy, Volume 81, Issue 8, Page 2582-2632, August 2026.
ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
Torsten Zuberbier +221 more
wiley +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source

humans
histamine
animals

3. good health
cimetidine
ranitidine

gastric juice
dogs
peptic ulcer