Results 71 to 80 of about 39,913 (287)
Health Science Reports, Volume 9, Issue 1, January 2026.ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam +10 more
wiley +1 more source
The relation between antihistamine medication during early pregnancy & birth defects
Egyptian Journal of Medical Human Genetics, 2015 Antihistamines are a group of medications which can inhibit various histaminic actions at one of two histamine receptors (H1 or H2). H1 receptor antagonists are used for the relief of allergic dermatological and nondermatological conditions.
Rabah M. Shawky, Neveen S. Seifeldin
doaj +1 more source
PLoS ONE, 2020 In this population-based propensity score matched (PSM) cohort study, we aimed to investigate the risk of developing dementia with the use of acid suppressants, including proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2 antagonists).
Chia-Liang Wu +5 more
doaj +1 more source
The association between histamine 2 receptor antagonist use and Clostridium difficile infection: a systematic review and meta-analysis. [PDF]
, 2013 Background Clostridium difficile infection (CDI) is a major health problem. Epidemiological evidence suggests that there is an association between acid suppression therapy and development of CDI.
A Deshpande +69 more
core +3 more sources
Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry
ChemistryOpen, Volume 15, Issue 1, January 2026.Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten +5 more
wiley +1 more source
Frontiers in Oncology, 2019 Cancer microenvironment is complex and consists of various immune cells. There is evidence for mast cell (MC) infiltration of tumors, but their role thereof is poorly understood.
Sandeep Paudel +2 more
doaj +1 more source
Signal transduction mechanism of biased ligands at histamine H2 receptors [PDF]
, 2014 7TMRs (seven-transmembrane receptors) exist as conformational collections in which different conformations would lead to differential downstream behaviours such as receptor phosphorylation, G-protein activation and receptor internalization.
Alonso, Natalia +5 more
core +1 more source
A Mechanism‐Based Multi‐Level Population PK/PD Model for Potassium‐Competitive Acid Blockers
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.Schematic overview of a mechanism‐based, multi‐level population model for potassium‐competitive acid blockers. ABSTRACT Potassium‐competitive acid blockers (PCABs) are emerging alternatives to proton pump inhibitors for the treatment of acid‐related diseases.
Woojin Jung +6 more
wiley +1 more source
Scientific Reports, 2019 The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions.
Zane Stromberga +2 more
semanticscholar +1 more source