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Mast cells activated by SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine storm and inflammatory reaction in COVID-19.

Journal of Biological Regulators and Homeostatic Agents, 2020
SARS-CoV-2 virus is an infectious agent commonly found in certain mammalian animal species and today also in humans. SARS-CoV-2, can cause a pandemic infection with severe acute lung injury respiratory distress syndrome in patients with COVID-19, that ...
P. Conti   +9 more
semanticscholar   +1 more source

Histamine releasing factors

Clinical & Experimental Allergy, 1991
Histamine-releasing factors (HRF) are cell-derived products which cause histamine release from basophils and/or mast cells. We have isolated HRF from human mononuclear cells and platelets and have purified 3 molecular species having molecular weights of 8–10, 15–17 and 35–41 kilodaltons (kDa).
A P, Kaplan   +3 more
openaire   +3 more sources

Learned Histamine Release

Science, 1984
Most of the effort directed at understanding the problems of allergy has focused on the interacting components of the immune system. The possibility that histamine may be released as a learned response has now been tested. In a classical conditioning procedure in which an immunologic challenge was paired with the presentation of an odor, guinea pigs ...
M, Russell   +5 more
openaire   +2 more sources

Histamine Release by Anaphylatoxin

Nature, 1951
EARLY studies of the mechanism of anaphylaxis led to two apparently contradictory views : the so-called ‘humoral theory’, according to which the blood is the site of production of a toxin, the anaphylatoxin1–4; and the ‘cellular theory’, which localizes the anaphylactic reaction in the cells, and assumes that this reaction causes the release of ...
M, ROCHA E SILVA, O, BIER, M, ARONSON
openaire   +2 more sources

Histamine Release by Contrast Media

Radiology, 1971
The blood draining organs with a high histamine content was sampled and elevation of plasma histamine was found to result from injections of certain contrast media. All methylglucamine contrast media tested to date (acetrizoate, diatrizoate, and iodipamide) produced such elevations.
E C, Lasser   +3 more
openaire   +2 more sources

Histamine Storage and Release

Proceedings, annual meeting, Electron Microscopy Society of America, 1973
Isolated rat peritoneal mast cells respond to compound 48/80 and to antigen with degranulation and histamine (Hi) release. In electronmicroscopic studies the initial structural changes were seen at the periphery of the cell immediately adjacent to the cell membrane, indicating that the effect of compound 48/80 (and of antigen) starts from the cell ...
openaire   +2 more sources

Myocardial infarction and histamine release

Agents and Actions, 1986
On the basis of previous data suggesting the involvement of cardiac histamine in ischemic heart disease (IHD), we evaluated plasma histamine (H) and creatine-kinase isoenzyme (CK-MB) level in cardiac and healthy subjects. 20 patients with acute myocardial infarction (AMI) (10 developing AMI in Hospital, thus making possible the detection of plasma H ...
F, Zaca   +7 more
openaire   +2 more sources

Histamine release in man

Agents and Actions, 1975
(1) Histamine release in man could be demonstrated using the fluorometric histamine assay in plasma as a reliable test. (2) Histamine release in animals may be relevant in some cases for human subjects, as shown for anaesthetic drugs and plasma substitutes on gelatin basis.
openaire   +2 more sources

Leucocyte Histamine Release in Migraine

Headache: The Journal of Head and Face Pain, 1980
SYNOPSIS Although histamine has been suggested as a possible vasoactive mediator in the pathogenesis of migraine, the mechanism of histamine release and its exact role in the pathophysiology of migraine is unclear. The spontaneous release of histamine from plasma‐free leucocyte suspensions was examined in 9 patients with 5 types of ...
W M, Sanders   +3 more
openaire   +2 more sources

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