Results 301 to 310 of about 147,237 (374)

Pharmacokinetics and Pharmacodynamics of Intravenous Magnesium Sulfate in Pediatric Acute Asthma Exacerbations

The Journal of Clinical Pharmacology, Volume 65, Issue 6, Page 665-674, June 2025.
Abstract Pediatric asthma exacerbations represent a significant cause of emergency department use and hospitalizations. Despite available treatment options, many children's exacerbations are refractory to standard therapies and require adjunct treatments.
Joseph E. Rower, Michael D. Johnson, Joseph J. Zorc, Bashar Shihabuddin, Mengtao Dai, Bradley J. Barney, Yaron Finkelstein   +6 more
wiley   +1 more source

First demonstration of implication of hereditary alpha-tryptasaemia in vasospastic angina: a case report. [PDF]

Eur Heart J Case Rep
Caullery B, Bocquet A, Riou L, Barone-Rochette G.   +3 more
europepmc   +1 more source

Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling

British Journal of Pharmacology, Volume 182, Issue 12, Page 2585-2602, June 2025.
Abstract Background and Purpose Vasoreactivity of pulmonary arteries regulates blood flow through the lungs. Excessive constriction of these vessels contributes to pulmonary arterial hypertension (PAH), a progressive and incurable condition, resulting in right heart failure.
Adam L. Fellows, Kate Quigley, Venus Leung, Alexander J. Ainscough, Martin R. Wilkins, Harry Barnett, David Miller, Manuel Mayr, Beata Wojciak‐Stothard   +8 more
wiley   +1 more source

Time-sensitive effects of quercetin on rat basophilic leukemia (RBL-2H3) cell responsiveness and intracellular signaling. [PDF]

PLoS One
Matsuo M, Liu S, Yamada H, Takemasa E, Suzuki Y, Mogi M.   +5 more
europepmc   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, Volume 42, Issue 6, June 2025.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source

Estimation of serum levels of mast cells-related chymase, histamine and diamine oxidase in oral submucous fibrosis- a preliminary report. [PDF]

BMC Oral Health
Gharote H, Panchbhai A, Joshi D.
europepmc   +1 more source

Type 2 Inflammation and Its Role in Dermatologic Diseases

International Journal of Dermatology, Volume 64, Issue 6, Page 978-991, June 2025.
ABSTRACT Atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria are immune‐mediated, inflammatory skin conditions characterized by intense itch and disease‐specific skin lesions. Despite their different clinical presentations, the three diseases are unified by an aberrant type 2 immune response involving type 2 cytokines, immune cells,
Raj Chovatiya, Jason E. Hawkes, Douglas DiRuggiero, Leigh Ann Pansch, Elizabeth Simcox, Tayler Gonzalez   +5 more
wiley   +1 more source

Quercetin and Its Lecithin-Based Formulation: Potential Applications for Allergic Diseases Based on a Narrative Review. [PDF]

Nutrients
Naso M, Trincianti C, Tosca MA, Ciprandi G.   +3 more
europepmc   +1 more source

Single‐cell sequencing reveals a regulatory role of WT1 in mast cell proliferation in endometrial polyps

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
We used single‐cell and bulk RNA sequencing to analyze ectopic endometrial polyps (EPs) and adjacent eutopic endometrial tissues (EUs), identifying alterations in cell composition and transcriptional dynamics. Notably, mast cells showed increased activation with distinct transcriptional changes.
Yu Lin, Yiwen Qi, Yutong Yao, Huan Tong, Lan Chen, Weizhou Song, Guojing Li, Hong Xu, Xiaoying He   +8 more
wiley   +1 more source

Effects of <i>Astragalus membranaceus</i> Leaf Extract on Allergic Inflammation in Immune Cell Lines. [PDF]

Prev Nutr Food Sci
Bunddulam P, Nakamura M, Zorig A, Hinata Y, Takasugi M, Feng CH, Sato T, Arai H.   +7 more
europepmc   +1 more source