Results 51 to 60 of about 2,226,679 (338)

Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

Frontiers in Cell and Developmental Biology, 2022
Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma.
Roberto Berra-Romani, Ajelet Vargaz-Guadarrama, Josué Sánchez-Gómez, Nayeli Coyotl-Santiago, Efraín Hernández-Arambide, José Everardo Avelino-Cruz, Mario García-Carrasco, Monica Savio, Giorgia Pellavio, Umberto Laforenza, Alfredo Lagunas-Martínez, Francesco Moccia   +11 more
doaj   +1 more source

Organic cation transporter-3 mediates exogenous histamine uptake by primary mast cells

Journal of Allergy and Clinical Immunology: Global
Background: Mast cells exhibit uptake of histamine from the extracellular microenvironment, which can affect the extent of histamine release following their activation. How mast cells take up exogenous histamine, however, is not fully understood. Organic
Thuy-An Nguyen, MD, Yuki Nakamura, PhD, Kentaro Yoshimura, PhD, Hiroaki Nagatomo, PhD, Keishi Narita, PhD, Nguyen Quoc Vuong Tran, MD, PhD, Kayoko Ishimaru, MS, Yoshiaki Kobayashi, MD, Nobuhiro Nakano, PhD, Satoshi Tanaka, PhD, Yoshiaki Shinohara, MD, PhD, Atsuhito Nakao, MD, PhD   +11 more
doaj   +1 more source

Histamine release by sodium chloroplatinate [PDF]

British Journal of Pharmacology, 1969
The chloroplatinate ion can release histamine from the tissues in various species of animals. This property is not shared by other complex ions with co‐ordination number 6, or other complex platinum ions. The release of histamine may form the basis of the known disease platinosis which affects people who work in platinum refineries, and which is ...
A, Saindelle, F, Ruff
openaire   +2 more sources

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

HISTAMINE RELEASE AND CHANDONIUM IODIDE [PDF]

Medical Journal Armed Forces India, 1996
Histamine releasing activity of chandonium iodide and d-tubocurarine was studied in guinea pig ileum (in vitro), guinea pig peritoneum (in vivo) and in human volunteers (in vivo) by intradermal testing at dilutions of 1:1,000 and 1:10,000 of the clinical dosage of drugs. d-tubocurarine revealed significant histamine releasing activity in in vivo animal
Y V, Suri, B B, Nayak, M, Jaiprakash
openaire   +2 more sources

Per‐ and polyfluoroalkyl substances and hand osteoarthritis: data from the Osteoarthritis Initiative

Arthritis &Rheumatology, Accepted Article.
Objective To explore whether biological levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS – reflecting the overall effect and accounting for correlations among each PFAS – relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban, Lisa B. Rokoff, Bing Lu, Timothy E. McAlindon, Charles B. Eaton, Mary B. Roberts, Diana Mathes, Colleen Lestician, Zhijin Carrie Xu, Zhihua Tina Fan, Shawn P. O'Leary, Ida K. Haugen, Jérémie Sellam, Alice Courties, Abby F. Fleisch   +14 more
wiley   +1 more source

Role of histamine in the inhibitory effects of phycocyanin in experimental models of allergic inflammatory response

Mediators of Inflammation, 2002
It has recently been reported that phycocyanin, a biliprotein found in the blue-green microalgae Spirulina, exerts anti-inflammatory effects in some animal models of inflammation.
D. Remirez, N. Ledón, R. González
doaj   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Recombinant IL-3 induces histamine release from human basophils.

Journal of Immunology, 1989
Human rIL-3 induces histamine release from some human basophils, with cells from atopics responding to a greater extent than non-atopic donors. The dose response curves were highly variable.
Shannon M. MacDonald, R. P. Schleimer, A. Kagey-sobotka, S. Gillis, L. Lichtenstein   +4 more
semanticscholar   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source