Factors in the Iodination of Histidine in Proteins [PDF]
J. Wolff, I Covelli
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HCN2‐Associated Neurodevelopmental Disorders: Data from Patients and Xenopus Cell Models
Objective We aimed to characterize the phenotypic spectrum and functional consequences associated with variants in HCN2, encoding for the hyperpolarization‐activated cyclic nucleotide (HCN) gated channel 2. Methods GeneMatcher facilitated the recruitment of 21 individuals with HCN2 variants from 15 unrelated families, carrying HCN2 variants.
Clara Houdayer+52 more
wiley +1 more source
Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof
PsiK from Psilocybe cubensis phosphorylates a diverse set of substituted phenols and benzenediols beyond its native substrate. High‐throughput screening of active site mutant libraries using DESI‐MS enabled protein engineering of PsiK, further expanding its substrate scope.
Ahram Kim+8 more
wiley +2 more sources
The Reaction between Mercury(II) and Organic Compounds. II. The Composition of a Mercury(II)-L-Histidine Complex in an Ethanol-Water Solution [PDF]
Fumiaki Kai
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The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He+11 more
wiley +1 more source
Induction of the specific histidine decarboxylase by TSH and 2-mercaptobenzimidazole-1,3-dimethylol (MBI) [PDF]
W. Lorenz, M. Gerant, E Werle
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Endogenously Triggered DNAzyme‐Based Nanostructures for Gene‐Combined Therapy
DNAzymes show great promise for gene regulation and therapeutic use via controlled release triggered by endogenous factors. This review summarizes recent advances in designing and constructing nanoscale platforms enabling endogenously triggered release of DNAzyme.
Theoneste Muyizere+4 more
wiley +1 more source
Photocontrolled Release of Urea Enables the Detection of Urea–Urease Intermediates by Cryo‐FTIR
Urease is a fast enzyme, presenting kcat of the order of 103–104 s−1. To enable the visualization of its mechanism we explored the technique of cryo‐FTIR. By means of using a ruthenium complex as a caged‐urea, upon light irradiation urea was released and we could see the coordination of the urea to the active site.
Caterina G.C. Marques Netto+7 more
wiley +2 more sources