Results 171 to 180 of about 228,380 (298)

N‐Amino Peptide–Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

open access: yesAdvanced NanoBiomed Research, EarlyView.
A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu   +5 more
wiley   +1 more source

Chirality Makes or Breaks Chemically Driven Self‐Assembly

open access: yesAngewandte Chemie, EarlyView.
Chirality‐controlled reaction cycles: Reaction cycles are constructed to respond to the chirality (handedness) of an acylating agent. Left‐ and right‐handed aminoacyl phosphate esters modulate the structure, lifetime, and transformation of transient (thio)ester intermediates, enabling control over distinct chemical pathways using molecules that are ...
Lenard Saile   +5 more
wiley   +2 more sources

STUDIES ON THE HISTIDINE-HISTAMINE RELATIONSHIP IN VIVO [PDF]

open access: bronze, 1968
Margaret A. Reilly, Richard W. Schayer
openalex   +1 more source

Correction: Proximity-induced SuFEx increases the potency of cytosolic nucleotidase inhibitors and reveals a rare example of covalently targeted histidine. [PDF]

open access: yesRSC Chem Biol
Chrominski M   +8 more
europepmc   +1 more source

Fortification of FeS Clusters Reshapes Anaerobic CO Dehydrogenase into an Air‐Viable Enzyme Through Multilayered Sealing of O2 Tunnels

open access: yesAngewandte Chemie, EarlyView.
Fortification of FeS clusters in Ni─Fe CO dehydrogenase (Carboxydothermus hydrogenoformans) reshapes this anaerobic enzyme into an air‐viable variant through multilayered O2 tunnel sealing. The engineered enzyme retains structural integrity and catalytic efficiency in ambient air, offering a practical solution for industrial CO/CO2 bioconversion ...
Suk Min Kim   +9 more
wiley   +2 more sources

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