Results 71 to 80 of about 164 (159)
The Metabolism of Histidine [PDF]
Journal of Biological Chemistry, 1957 Charles D. Tourtellotte +1 more
openaire +2 more sources
Angewandte Chemie, EarlyView.Ein Biosyntheseweg für den Polymervorläufer Tulipalin A ausgehend von Isoprenylacetat wird hier präsentiert. Die Alkan‐Monooxygenase AlkB katalysiert die chemo‐ und regioselektive terminale Hydroxylierung von Isoprenylacetat und die Aktivität konnte durch rationelles Engineering des Membranenzyms weiter gesteigert werden. Die vollständige Oxidation zur
Andrea Nigl +11 more
wiley +1 more source
Angewandte Chemie International Edition, EarlyView.Small but crucial difference: Type‐III copper enzymes, like tyrosinase (TYR) and o‐aminophenol oxidase (AO), catalyze the oxidation of o‐aminophenols (AP) to quinone imines. Unlike TYR, AO can further oxidize AP to nitrosophenols. This nitroso‐forming activity is controlled by a key amino acid near the Cu(A) ion.
Hoa Le Xuan, Felix Panis, Annette Rompel
wiley +1 more source
Angewandte Chemie International Edition, EarlyView.A biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme.
Andrea Nigl +11 more
wiley +1 more source
Photo‐controlled Release of Urea Enables the Detection of Urea‐Urease Intermediates by cryo‐FTIR
Angewandte Chemie International Edition, Accepted Article.Caged compounds are a valuable tool to photocontrol the release of enzymatic substrates in a reaction. For example, caged urea molecules were proposed to control urea delivery to urease reactions and aid the determination of the catalytic mechanism of this enzyme.
Caterina Netto +7 more
wiley +1 more source
Redirecting the Peptide Cleavage Causes Protease Inactivation
Angewandte Chemie International Edition, Accepted Article.Cysteine and serine proteases cleave peptides through covalent catalysis by generating a transient adduct with the N‐terminal part of the substrate after releasing its C‐terminal part. We demonstrate the unique redirection of this event leading to strong enzyme inactivation.
Michael Gütschow +20 more
wiley +1 more source
Angewandte Chemie International Edition, Accepted Article.The inherent O2 sensitivity of Ni–Fe carbon monoxide dehydrogenases (CODHs), crucial for rapid CO to CO2 interconversion, presents substantial challenges for industrial application. Transforming CO/CO2, a prevalent anthropogenic air pollutant, into valuable carbon chemicals either directly or through intermediate steps via biocatalytic methods offers a
Yong Hwan Kim +9 more
wiley +1 more source
Analysis of plant metabolomics data using identification‐free approaches
Applications in Plant Sciences, EarlyView.Abstract Plant metabolomes are structurally diverse. One of the most popular techniques for sampling this diversity is liquid chromatography–mass spectrometry (LC‐MS), which typically detects thousands of peaks from single organ extracts, many representing true metabolites.
Xinyu Yuan +2 more
wiley +1 more source