Results 71 to 80 of about 265,522 (247)
The spatial orientation of histidine via five-armed alkylamino siloxane improved the properties of the cationic gene delivery vector [PDF]
Biofunctional MaterialsThe efficiency of gene transfection using cationic polymers primarily depends on factors such as compact polyplex formation, cellular uptake, endosomal escape, cytoplasmic transport, nuclear entry, and the dissociation and release of plasmid from the ...
Viola B. Morris, Chandra P. Sharma
doaj +1 more source
Advanced Materials, EarlyView.The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim +12 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Conversion of Histidine to Hercynine by Neurospora crassa [PDF]
, 1970 Vernon N. Reinhold +2 more
openalex +1 more source
Remediation of cationic and anionic dyes from water by histidine modified mesoporous silica
, 2021 Abdullah M. Alswieleh
openalex +2 more sources
Advanced Porous Materials for Maritime Carbon Capture
Advanced Materials, EarlyView.Carbon capture from emission sources, such as marine vessels, has attracted significant attention over the years. To achieve this goal, sorbents such as metal–organic frameworks (MOFs), porous polymer networks (PPNs), covalent organic frameworks (COFs), and their post‐synthetic modifications are currently being explored.
Kelechi Festus +6 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH2) with different ratios of two relevant amino ...
Fatemeh Sheikhi Mehrabadi +5 more
doaj +1 more source
Role of
, 2005 Ileana C. Fărcăşanu +3 more
openalex +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid
Advanced Science, EarlyView.α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė +7 more
wiley +1 more source