Results 71 to 80 of about 186,471 (141)

Histidine Metabolic Pathway Modifies the Relationships Between 6:2 Cl-PFESA Exposure and Preterm Birth

Toxics
Background: Evidence linking chlorinated polyfluoroalkyl ether sulfonic acids (Cl-PFESAs) to preterm birth (PTB) is limited, and their relationships with the metabolome remain unexplored. Aims: Our study aimed to explore the role of the metabolome in the
Jianping Cong, Chu Chu, Zhitao Zhang, Gaoyuan Sun, Yan Zhang, Aaron M. Qian, Michael G. Vaughn, Sarah Dee Geiger, Kun Zhao, Yunting Zhang, Yang Zhou, Zhihua Yin, Guanghui Dong   +12 more
doaj   +1 more source

Design, Synthesis, and Evaluation of Homochiral Peptides Containing Arginine and Histidine as Molecular Transporters

Molecules, 2018
Linear (HR)n and cyclic [HR]n peptides (n = 4,5) containing alternate arginine and histidine residues were synthesized. The peptides showed 0–15% cytotoxicity at 5–100 µM in human ovarian adenocarcinoma (SK-OV-3) cells while they ...
Naglaa Salem El-Sayed, Taryn Miyake, Amir N. Shirazi, Shang Eun Park, Jimmy Clark, Stephani Buchholz, Keykavous Parang, Rakesh Tiwari   +7 more
doaj   +1 more source

Split histidine kinases enable ultrasensitivity and bistability in two-component signaling networks [PDF]

, 2012
Bacteria sense and respond to their environment through signaling cascades generally referred to as two-component signaling networks. These networks comprise histidine kinases and their cognate response regulators.
Amin, Munia, Porter, Steven L., Soyer, Orkun S.   +2 more
core   +3 more sources

Effects of reduced metabolizable protein diets supplemented with rumen-protected His under adequate Met and Lys supply on production, nutrient digestibility, N utilization, and manure ammonia emissions in lactating cows

Journal of Dairy Science
: Balancing for limiting AA may prevent reduced production when deficient MP is provided. The objective of the study was to determine the effects of rumen-protected (RP) His supplementation at different levels of MP when Lys and Met supplies meet the ...
K. Park, J. Kim, H. Hu, M. Kambara, K. Nakagawa, C. Lee   +5 more
doaj   +1 more source

Global regulation and virulence mediated by the histidine-responsive local transcription factor HutC in Pseudomonas aeruginosa

mBio
Host-derived nutritional substrates fuel infection in invading bacteria, yet their potential as signaling molecules for host perception remains largely unexplored.
Kiran S. Jayan, Naran Naren, Yunhao Liu, Xinyi Liu, Chang Luan, Xue-Xian Zhang   +5 more
doaj   +1 more source

Histidine Alleviates Impairments Induced by Chronic Cerebral Hypoperfusion in Mice

Frontiers in Physiology, 2018
Chronic cerebral hypoperfusion is one of the fundamental pathological causes of brain disease such as vascular dementia. Exploration of effective treatments for this is of great interest.
Jiangman Song, Lu Yang, Di Nan, Qihua He, You Wan, Huailian Guo, Huailian Guo   +6 more
doaj   +1 more source

EPR of Cu\u3csup\u3e2+\u3c/sup\u3e Prion Protein Constructs at 2 GHz Using the \u3cem\u3eg\u3c/em\u3e\u3csub\u3e⊥\u3c/sub\u3e Region to Characterize Nitrogen Ligation [PDF]

, 2009
A double octarepeat prion protein construct, which has two histidines, mixed with copper sulfate in a 3:2 molar ratio provides at most three imidazole ligands to each copper ion to form a square-planar Cu2+ complex.
Antholine, William E., Bennett, Brian, Hyde, James S, Millhauser, Glenn L., Sidabras, Jason Walter, Walter, Eric D.   +5 more
core   +1 more source

Towards an Understanding of the Molecular Basis of Nickel Hyperaccumulation in Plants

Plants, 2019
Metal hyperaccumulation is a rare and fascinating phenomenon, whereby plants actively accumulate high concentrations of metal ions in their above-ground tissues.
Llewelyn van der Pas, Robert A. Ingle
doaj   +1 more source

L-Histidinin tespiti için CNT Destekli Bimetalik Ru-Mo Katalizörü

Van Yüzüncü Yıl Üniversitesi Mühendislik Fakültesi Dergisi
Bu çalışmada, karbon nanotüp (CNT) destekli Ru-Mo bimetalik katalizörle modifiye edilmiş camsı karbon elektrot (GCE) ile bir voltametrik L-Histidin (His) sensörü geliştirilmektedir.Ru-Mo/CNT, katalizörü, sodyum borohidrit indirgeme yöntemiyle hazırlandı.
Ömrüye Özok Arıcı, Hilal Demir Kıvrak, Aykut Çağlar, Arif Kıvrak   +3 more
doaj  

Beyond Peptides and Peptidomimetics: Natural Heteroaromatic Amino Acids in the Synthesis of Fused Heterocyclic Frameworks for Bioactive Agents

Organics
Heterocycle cores are widely used in medicinal chemistry for developing bioactive compounds. In this scenario, using cheap and accessible starting material to build these heterocycles is desirable to obtain new drug candidates for cost-efficient ...
Isis Apolo Silveira de Borba, Jamile Buligon Peripolli, Angélica Rocha Joaquim, Fernando Fumagalli   +3 more
doaj   +1 more source