Results 91 to 100 of about 308,029 (295)
Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin
Advanced Healthcare Materials, EarlyView.Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi +2 more
wiley +1 more source
Reactivation of Serratia marcescens Endonuclease NucSma(H89G) by Hydroxilamine [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2017 Serratia marcescens endonuclease is the most nonspecific nuclease known. This nuclease refers to enzymes that can cleave both DNA and RNA. The active site of this enzyme is characterized by the H–N–H motif, but more important functions have been shown ...
R.G. Khamidullina +2 more
doaj
Characterization of the novel Maurer's clefts protein MAHRP1 in "Plasmodium falciparum" [PDF]
, 2007 Plasmodium falciparum causes the worst form of human malaria and is responsible for 1-2 million deaths annually. A vaccine is not available and resistance to drugs is widespread.
Spycher, Anna Cornelia
core +1 more source
Advanced Materials, EarlyView.Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi +3 more
wiley +1 more source
FASEB BioAdvancesDeuterium is a natural heavy isotope of hydrogen, having a neutron as well as a proton. Deuterium disrupts ATP synthesis in mitochondria, causing increased production of reactive oxygen species and reduced synthesis of ATP.
Stephanie Seneff +2 more
doaj +1 more source
Molecules, 2018 Linear (HR)n and cyclic [HR]n peptides (n = 4,5) containing alternate arginine and histidine residues were synthesized. The peptides showed 0–15% cytotoxicity at 5–100 µM in human ovarian adenocarcinoma (SK-OV-3) cells while they ...
Naglaa Salem El-Sayed +7 more
doaj +1 more source
Turning Water Into a Tool: From Degradation Pathways to Functional Engineering in Halide Perovskites
Advanced Materials Technologies, EarlyView.Water exhibits a threshold‐dependent dual role in lead halide perovskites, acting either as a degradation trigger or as a powerful tool for defect passivation, recrystallization, and structural engineering. This review discusses how controlled water‐mediated interactions govern stability, dimensionality, and optoelectronic performance, providing ...
Raphaella T. S. Gonçalves +4 more
wiley +1 more source
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L) [PDF]
, 2009 Purpose: Elevated levels of dietary histidine have previously been shown to prevent or mitigate cataract formation in farmed Atlantic salmon (Salmo salar L). The aim of this study was to shed light on the mechanisms by which histidine acts.
Breck, Olav +5 more
core
Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]
, 2012 In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Pan-Ngum Wirichada +127 more
core +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
Advanced Science, EarlyView.ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source