Results 111 to 120 of about 291,783 (305)

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]

, 2012
In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Pan-Ngum Wirichada, George Mtove (124816), Gesase Samwel, Woodrow, Charles, Saiwaew, Somporn, Mwanga-Amumpaire Juliet, Fanello, CI, Kathryn Maitland, Ermelinda Gomes, Sarah Joseph (140503), White, Lisa, Nicholas J. White (35779), Ilse C E Hendriksen, Arjen M Dondorp, Gomes, Ermelinda, Samwel Gesase, Charles Woodrow, Sue J. Lee (140486), Rasaq Olaosebikan, Kesinee Chotivanich (140505), Fanello, Caterina I, Nicholas J White, Hendriksen Ilse C. E., White Nicholas J., von Seidlein Lorenz, Tshefu, Antoinette K, Antoinette K. Tshefu (140488), Sarah Joseph, von Seidlein, Lorenz, Antoinette K Tshefu, Lee, Sue, Silamut, Kamolrat, Tshefu Antoinette K., Woodrow, C, Corine Karema (140493), Ilse C. E. Hendriksen (140479), Mwanga-Amumpaire, J, Day Nicholas P. J., White Lisa J., White, Nicholas J, Caterina I. Fanello (140506), Maitland, K, Lee Sue J., Nicholas P J Day, Dondorp, Arjen M, Kamolrat Silamut (140501), Maitland Kathryn, Woodrow Charles, Dondorp, Adrianus, Arjen M. Dondorp (140509), Reyburn, Hugh, Day, Nicholas P J, Tshefu, AK, Day, Nicholas, Sue J Lee, Corine Karema, Juliet Mwanga-Amumpaire (140482), White, NJ, Lorenz von Seidlein (45473), Amos Ben, White, Lisa J, Lisa J White, Maitland, Kathryn, Amos, Ben, Somporn Saiwaew (140495), Silamut Kamolrat, Olaosebikan, Rasaq, Gomes, E, Lorenz von Seidlein, Pan-Ngum, W, Mtove, G, Samwel Gesase (140499), Hendriksen, ICE, Wirichada Pan-Ngum (2583205), Nicholas P. J. Day (35781), George Mtove, Joseph, Sarah, Gesase, Samwel, Hendriksen, IC, Chotivanich Kesinee, Saiwaew, S, Lisa J. White (101780), Hendriksen, Ilse C E, von Seidlein, L, Fanello Caterina I., Hugh Reyburn (45198), Reyburn Hugh, Juliet Mwanga-Amumpaire, Charles Woodrow (140489), Hendriksen, AM, Ben Amos (140491), Lee, Sue J, Gomes Ermelinda, Chotivanich, Kesinee, Wirichada Pan-Ngum, White, Nicholas, White, LJ, Ben Amos, Dondorp, AM, Gesase, S, Pan-Ngum, Wirichada, Mwanga-Amumpaire, Juliet, Amos, B, Karema, C, Day, NP, Joseph, S, Day, NPJ, Karema Corine, Saiwaew Somporn, Joseph Sarah, Karema, Corine, Lee, SJ, Chotivanich, K, Ermelinda Gomes (140497), Somporn Saiwaew, Kamolrat Silamut, Reyburn, H, Hugh Reyburn, Kesinee Chotivanich, Rasaq Olaosebikan (130780), Olaosebikan Rasaq, Kathryn Maitland (21356), Dondorp Arjen M., Silamut, K, Mtove George, Olaosebikan, R, Mtove, George, Caterina I Fanello   +127 more
core   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Towards an Understanding of the Molecular Basis of Nickel Hyperaccumulation in Plants

Plants, 2019
Metal hyperaccumulation is a rare and fascinating phenomenon, whereby plants actively accumulate high concentrations of metal ions in their above-ground tissues.
Llewelyn van der Pas, Robert A. Ingle
doaj   +1 more source

Turning Water Into a Tool: From Degradation Pathways to Functional Engineering in Halide Perovskites

Advanced Materials Technologies, EarlyView.
Water exhibits a threshold‐dependent dual role in lead halide perovskites, acting either as a degradation trigger or as a powerful tool for defect passivation, recrystallization, and structural engineering. This review discusses how controlled water‐mediated interactions govern stability, dimensionality, and optoelectronic performance, providing ...
Raphaella T. S. Gonçalves, Gabriela O. Gera, Aryane Tofanello, Jose A. Souza, Andre L. M. Freitas   +4 more
wiley   +1 more source

L-Histidinin tespiti için CNT Destekli Bimetalik Ru-Mo Katalizörü

Van Yüzüncü Yıl Üniversitesi Mühendislik Fakültesi Dergisi
Bu çalışmada, karbon nanotüp (CNT) destekli Ru-Mo bimetalik katalizörle modifiye edilmiş camsı karbon elektrot (GCE) ile bir voltametrik L-Histidin (His) sensörü geliştirilmektedir.Ru-Mo/CNT, katalizörü, sodyum borohidrit indirgeme yöntemiyle hazırlandı.
Ömrüye Özok Arıcı, Hilal Demir Kıvrak, Aykut Çağlar, Arif Kıvrak   +3 more
doaj  

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Beyond Peptides and Peptidomimetics: Natural Heteroaromatic Amino Acids in the Synthesis of Fused Heterocyclic Frameworks for Bioactive Agents

Organics
Heterocycle cores are widely used in medicinal chemistry for developing bioactive compounds. In this scenario, using cheap and accessible starting material to build these heterocycles is desirable to obtain new drug candidates for cost-efficient ...
Isis Apolo Silveira de Borba, Jamile Buligon Peripolli, Angélica Rocha Joaquim, Fernando Fumagalli   +3 more
doaj   +1 more source

Deuterium MAS NMR Studies of Dynamics on Multiple Timescales: Histidine and Oxalic Acid. [PDF]

, 2014
International audience ; Deuterium ((2) H) magic-angle spinning (MAS) nuclear magnetic resonance is applied to monitor the dynamics of the exchanging labile deuterons of polycrystalline L-histidine hydrochloride monohydrate-d7 and α-oxalic acid dihydrate-
Gervais, Christel, Chan-Huot, Monique, Bodenhausen, Geoffrey, Duma, Luminita, Wimperis, Stephen   +4 more
core   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Knocking out histidine ammonia-lyase by using CRISPR-Cas9 abolishes histidine role in the bioenergetics and the life cycle of Trypanosoma cruzi

Microbial Cell
Trypanosoma cruzi, the causing agent of Chagas disease, is the only known trypanosomatid pathogenic to humans having a complete histidine to glutamate pathway, which involves a series of four enzymatic reactions that convert histidine into downstream ...
Janaína de Freitas Nascimento, María Julia Barisón, Gabriela Torres Montanaro, Letícia Marchese, Rodolpho Ornitz Oliveira Souza, Letícia Sophia Silva, Alessandra Aparecida Guarnieri, Ariel Mariano Silber   +7 more
doaj   +1 more source