Results 111 to 120 of about 435,238 (305)

L-Histidinin tespiti için CNT Destekli Bimetalik Ru-Mo Katalizörü

Van Yüzüncü Yıl Üniversitesi Mühendislik Fakültesi Dergisi
Bu çalışmada, karbon nanotüp (CNT) destekli Ru-Mo bimetalik katalizörle modifiye edilmiş camsı karbon elektrot (GCE) ile bir voltametrik L-Histidin (His) sensörü geliştirilmektedir.Ru-Mo/CNT, katalizörü, sodyum borohidrit indirgeme yöntemiyle hazırlandı.
Ömrüye Özok Arıcı, Hilal Demir Kıvrak, Aykut Çağlar, Arif Kıvrak   +3 more
doaj  

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Effects of Dietary Supplementation of Histidine, β-Alanine, Magnesium Oxide, and Blood Meal on Carnosine and Anserine Concentrations of Broiler Breast Meat

The Journal of Poultry Science, 2013
An experiment was conducted to evaluate the effect of dietary supplementation of histidine, β-alanine, blood meal (BM), magnesium oxide (MgO), and their combination on carnosine and anserine concentrations of broiler breast meat.
Se Won Park, Chan Ho Kim, Nyun Namgung, Byoung Yun Jung, In Kee Paik, Dong Yong Kil   +5 more
doaj   +1 more source

Ligand-dependent reactivity of the CysB5[23] b sulfhydryl group of the major haemoglobin of chicken [PDF]

, 1997
Chicken haemoglobin contains eight reactive sulfhydryl groups per (tetramer) molecule, as determined by Boyer titration with p-chloromercury(II)benzoic acid. However, only four of these sulfhydryls are reactive towards 5,5@-dithiobis(2-nitrobenzoic acid)
Nwozo, Sarah, Okonjo, K. O.
core  

Heme‐NO Dilates Arteries via Mobilization of NO Moieties From an Intracellular NO Store Within Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu, Meijuan Zhang, Lingchao Zhu, Haiyan Ke, Amancio de Souza, Qian Li, Daniel Castella, Nicolai Lehnert, Lubo Zhang, Arlin B. Blood   +9 more
wiley   +1 more source

Transferrin Conjugated pH- and Redox-Responsive Poly(Amidoamine) Dendrimer Conjugate as an Efficient Drug Delivery Carrier for Cancer Therapy

International Journal of Nanomedicine, 2020
Qing Hu,1,2,* Yifei Wang,1,* Lu Xu,1,* Dawei Chen,1,3 Lifang Cheng1 1Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, People’s Republic of China; 2Department of Pharmaceutics, College of ...
Hu Q, Wang Y, Xu L, Chen D, Cheng L
doaj  

UV-B induced alteration of oxygen evolving reactions in pea thylakoid membranes as affected by scavengers of reactive oxygen species

Biologia Plantarum, 2014
The effect of UV-B irradiation at temperatures of 22 and 4 °C on flash induced oxygen yields, photochemical activity, and energy transfer in pea thylakoid membranes in the absence and presence of scavengers of reactive oxygen species (ROS) was studied ...
D. Lazarova, D. Stanoeva, A. Popova, D. Vasilev, M. Velitchkova   +4 more
doaj   +1 more source

The protective effect of exercise on diabetic nephropathy : the role of histidine-containing dipeptides [PDF]

, 2017
C
Baba, Shahid P, Baelde, Hans, Delanghe, Joris, Derave, Wim, Everaert, Inge, Hanssens, Maxime, Hauske, Sibylle J, Yard, Benito A   +7 more
core   +1 more source

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source