Results 101 to 110 of about 308,029 (295)

Experimental Charge Densities and Intermolecular Interactions:  Electrostatic and Topological Analysis of dl-Histidine

, 2016
A high-resolution, low-temperature X-ray diffraction data set on dl-histidine, collected with a CCD detector, is used in the analysis of molecular bonding and intermolecular interactions. The molecular dipole moment in the crystal is enhanced relative to
Yuriy Abramov (2537785), Philip Coppens (1272102), Mark R. Pressprich (3006033), Irina Novozhilova (2962155), Cristobal Alhambra (3006027), Michael Carducci (3006036), Boris Korjov (3006030)   +6 more
core   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Histidine Alleviates Impairments Induced by Chronic Cerebral Hypoperfusion in Mice

Frontiers in Physiology, 2018
Chronic cerebral hypoperfusion is one of the fundamental pathological causes of brain disease such as vascular dementia. Exploration of effective treatments for this is of great interest.
Jiangman Song, Lu Yang, Di Nan, Qihua He, You Wan, Huailian Guo, Huailian Guo   +6 more
doaj   +1 more source

Molecular Dynamics Simulations Based on Newly Developed Force Field Parameters for Cu²⁺ Spin Labels Provide Insights into Double-Histidine-Based Double Electron–Electron Resonance

, 2020
Electron paramagnetic resonance (EPR) in combination with the recently developed double-histidine (dHis)-based Cu2+ spin labeling has provided valuable insights into protein structure and conformational dynamics.
Austin Gamble Jarvi (5184884), Xiaowei Bogetti (8626533), Junmei Wang (141197), Sunil Saxena (595882), Shreya Ghosh, Junmei Wang, Sunil Saxena, Xiaowei Bogetti, Austin Gamble Jarvi, Shreya Ghosh (5963075)   +9 more
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

L-Histidinin tespiti için CNT Destekli Bimetalik Ru-Mo Katalizörü

Van Yüzüncü Yıl Üniversitesi Mühendislik Fakültesi Dergisi
Bu çalışmada, karbon nanotüp (CNT) destekli Ru-Mo bimetalik katalizörle modifiye edilmiş camsı karbon elektrot (GCE) ile bir voltametrik L-Histidin (His) sensörü geliştirilmektedir.Ru-Mo/CNT, katalizörü, sodyum borohidrit indirgeme yöntemiyle hazırlandı.
Ömrüye Özok Arıcı, Hilal Demir Kıvrak, Aykut Çağlar, Arif Kıvrak   +3 more
doaj  

Towards an Understanding of the Molecular Basis of Nickel Hyperaccumulation in Plants

Plants, 2019
Metal hyperaccumulation is a rare and fascinating phenomenon, whereby plants actively accumulate high concentrations of metal ions in their above-ground tissues.
Llewelyn van der Pas, Robert A. Ingle
doaj   +1 more source

Histidine-Rich Cell-Penetrating Peptide for Cancer Drug Delivery and Its Uptake Mechanism

, 2019
In this work, we report a drug delivery system based on the pH-responsive self-assembly and -disassembly behaviors of peptides. Here, a systematically designed histidine-rich lipidated peptide (NP1) is presented to encapsulate and deliver an anticancer ...
Feng Wang, Zhongzheng Gui (4537411), P. Chen, Lei Zhang (38117), Pingkai Ouyang, P. Chen (37301), Lei Zhang, Jiang Xu, Grace Jin, Yong Ding, Toby Wang, Pingkai Ouyang (1909729), Matthew Martz (6376295), Jiang Xu (351121), Feng Wang (44414), Grace Jin (6376292), Zhongzheng Gui, Matthew Martz, Toby Wang (6376289), Yong Ding (108968)   +19 more
core   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source