Results 121 to 130 of about 291,783 (305)

Differences between β-Ala and Gly-Gly in the design of amino acids-based hydrogels

open access: yesBeilstein Journal of Organic Chemistry, 2010
Despite the continuous interest in organogels and hydrogels of low molecular weight gelators (LMWG), establishing the relationship between the molecular structure and the gelation mechanism is still a challenge.
Andreea Pasc   +3 more
doaj   +1 more source

Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy [PDF]

open access: yes, 2012
Renjith P Johnson,1* Chung-Wook Chung,2* Young-Il Jeong,2 Dae Hwan Kang,2 Hongsuk Suh,3 Il Kim,11WCU Centre for Synthetic Polymer Bioconjugate Hybrid Materials, Department of Polymer Science and Engineering, Pusan National University, Pusan, 2National ...
Chung CW   +11 more
core   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

open access: yesAdvanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy

open access: yesMolecules, 2019
Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials.
Brett H. Pogostin   +3 more
doaj   +1 more source

Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet [PDF]

open access: yes, 2012
[[abstract]]The effects of histidine, alanine and carnosine on activity and/or mRNA expression of lipogenic enzymes and sterol regulatory element-binding proteins (SREBPs) in liver and adipose tissue from high fat diet treated mice were examined ...
蒙美津;Mong, Mei-Chin;趙哲毅;Chao, Che-Yi;殷梅津;YIN, MEI-CHIN
core  

Molybdenum-L-Histidine Complexes [PDF]

open access: yes, 1964
L- Histidine is a very important amino acid and is widely distributed in living systems. In the growth and multiplication of animal cells, it was found that L-histidine is one of the amino acids that must be present.
Lee, Jiing-yun
core   +2 more sources

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

open access: yesAdvanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Highly Sensitive Amperometric Sensor for the Determination of Glucose at Histidine Stabilized Copper Nanospheres Decorated Multi-Walled Carbon Nanotubes

open access: yesInternational Journal of Electrochemical Science, 2016
Uniform sized copper nanospheres (CuNSs) were deposited at functionalised multiwalled carbon nanotubes (f-MWCNTs) modified glassy carbon electrode (GCE) through a simple electrochemical method.
Shen-Ming Chen   +3 more
doaj   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

open access: yesAdvanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

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