Results 1 to 10 of about 26,592 (294)

Molecular Regulation of Histamine Synthesis [PDF]

Frontiers in Immunology, 2018
Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the amino acid histidine through a reaction catalyzed by the enzyme histidine ...
Hua Huang, Hua Huang, Yapeng Li, Jinyi Liang, Jinyi Liang, Fred D. Finkelman, Fred D. Finkelman   +6 more
doaj   +2 more sources

Histidine Decarboxylase Expression in Human Melanoma [PDF]

Journal of Investigative Dermatology, 2000
Histamine has been implicated as one of the mediators involved in regulation of proliferation in both normal and neoplastic tissues. Histidine decarboxylase, the only enzyme that catalyzes the formation of histamine from L-histidine, is an essential regulator of histamine levels.
Gábor Szabad, József Tímár, Éva Pállinger, Zsuzsa Darvas, Randall L. Hoffman, Lajos Kemény, Jozsef Füresz, Andor Pivarcsi, Csaba Szalai, Sarolta Kárpáti, Zsuzsanna Bata-Csorgo, Mary Haak-Frendscho, Valéria László, Attila Dobozy, Attila Horváth, Hargita Hegyesi, M. Bencsáth, András Falus   +17 more
openaire   +5 more sources

Anti-Allergic Potential of Cinnamaldehyde via the Inhibitory Effect of Histidine Decarboxylase (HDC) Producing Klebsiella pneumonia [PDF]

Molecules, 2020
Allergy is an immunological disorder that develops in response to exposure to an allergen, and histamines mediate these effects via histidine decarboxylase (HDC) activity at the intracellular level.
Lorina I. Badger-Emeka, Promise Madu Emeka, Krishnaraj Thirugnanasambantham, Hairul Islam M. Ibrahim   +3 more
doaj   +2 more sources

A STUDY OF POTENTIAL HISTIDINE DECARBOXYLASE INHIBITORS [PDF]

British Journal of Pharmacology and Chemotherapy, 1960
A series of compounds has been examined for ability to inhibit histidine decarboxylase. Histidine analogues having substituents in the imidazole ring showed a wide variation in potency, but these were all much less active than α‐methyldopa [β‐(3,4‐dihydroxyphenyl)‐α‐methylalanine], the most potent known inhibitor of histidine decarboxylase.
D. M. Shepherd, D. Mackay
openaire   +5 more sources

Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice [PDF]

Journal of Diabetes Research, 2015
Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model.
Manal Alkan, François Machavoine, Rachel Rignault, Julie Dam, Michel Dy, Nathalie Thieblemont   +5 more
doaj   +2 more sources

Histidine decarboxylase activity in lactic acid bacteria from wine

OENO One, 1993
Histidine decarboxylase activity was investigated in 21 strains of lactic acid bacteria isolated from Argentinian wines. This activity is not widely distributed between them, and occurs significatively only in some strains of Lactobacillus hilgardii.
Marta Elena Farías, María Cristina Manca de Nadra, Graciela Celestina Rollan, Ana María Strasser de Saad   +3 more
doaj   +3 more sources

Review of the potential of bioactive compounds in seaweed to reduce histamine formation in fish and fish products [PDF]

Italian Journal of Food Safety
The formation of histamine in food is influenced by temperature, and histamine growth can be inhibited by maintaining a cold chain. However, simply relying on temperature control is insufficient, as certain bacteria can produce the enzyme histidine ...
Muhammad Maskur, Asep Awaludin Prihanto, Muhamad Firdaus, Rovina Kobun, Rahmi Nurdiani   +4 more
doaj   +2 more sources

L-histidine decarboxylase and Tourette's syndrome. [PDF]

N Engl J Med, 2010
Tourette's syndrome is a common developmental neuropsychiatric disorder characterized by chronic motor and vocal tics. Despite a strong genetic contribution, inheritance is complex, and risk alleles have proven difficult to identify. Here, we describe an analysis of linkage in a two-generation pedigree leading to the identification of a rare functional
Ercan-Sencicek AG, Stillman AA, Ghosh AK, Bilguvar K, O'Roak BJ, Mason CE, Abbott T, Gupta A, King RA, Pauls DL, Tischfield JA, Heiman GA, Singer HS, Gilbert DL, Hoekstra PJ, Morgan TM, Loring E, Yasuno K, Fernandez T, Sanders S, Louvi A, Cho JH, Mane S, Colangelo CM, Biederer T, Lifton RP, Gunel M, State MW.   +27 more
europepmc   +6 more sources

Genomic Analysis of Two Histamine-Producing Strains Isolated from Yellowfin Tuna [PDF]

Foods
Psychrotrophic Morganella spp. is a typical histamine producer commonly found in seafood, exhibiting a high histamine-producing capacity. In this study, two strains of Morganella (GWT 902 and GWT 904) isolated from yellowfin tuna were subjected to ...
Yazhe Wang, Di Wang, Shengjun Chen, Gang Yu, Zhenhua Ma, Ya Wei, Chunsheng Li, Yueqi Wang, Chaoming Shen, Yongqiang Zhao   +9 more
doaj   +2 more sources

Histidine Decarboxylase in Enterobacteriaceae Revisited [PDF]

Journal of Clinical Microbiology, 2004
ABSTRACT With a modification of Taylor's decarboxylation broth, histidine decarboxylase was detected in Enterobacter aerogenes , Morganella morganii , Raoultella ornithinolytica , and some strains of Citrobacter youngae and
Wauters, Georges, Avesani, Véronique, Charlier, Jacqueline, Janssens, Michèle, Delmée, Michel   +4 more
openaire   +5 more sources