Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway. [PDF]
, 2015 The ability to biosynthetically produce chemicals beyond what is commonly found in Nature requires the discovery of novel enzyme function. Here we utilize two approaches to discover enzymes that enable specific production of longer-chain (C5-C8) alcohols
Baker, David +7 more
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Molecular Biology of L-Histidine Decarboxylase
YAKUGAKU ZASSHI, 1994 L-Histidine decarboxylase (HDC) catalyzes the formation of histamine from L-histidine. This biogenic amine is known to exert various effects in physiological and pathological reactions. In contrast to the well-known mechanism of histamine action through its interaction with specific receptors, the mechanisms regulating HDC gene expression are not ...
K, Yatsunami, T, Fukui, A, Ichikawa
openaire +3 more sources
Role of histidine decarboxylase gene in the pathogenesis of Tourette syndrome. [PDF]
Brain Behav, 2022 Xu L +6 more
europepmc +1 more source
Histidine decarboxylase-positive lactic acid bacteria strains and the formation of histamine in ripened cheeses [PDF]
, 2018 The relationship between histidine decarboxylase-positive (hdc+) lactic acid bacteria (LAB) counts and the amounts of biogenic amines, particularly histamine, in cheeses made with and without LAB starter were investigated. Sixty LAB strains were isolated
Carbó Moliner, Rosa +3 more
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Quercetin Inhibition of Specific Histidine Decarboxylase
Experimental Biology and Medicine, 1964 SummaryQuercetin by an isotopic method has been shown to be an effective inhibitor of non-specific and specific (induced) histi-dine decarboxylase both in vivo and in vitro.
R D, SMYTH, R, LAMBERT, G J, MARTIN
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Acute ethanol treatment upregulates th1, th2 and hdc in larval zebrafish in stable networks
Frontiers in Neural Circuits, 2013 Earlier studies in zebrafish have revealed that acutely given ethanol has a stimulatory effect on locomotion in fish larvae but the mechanism of this effect has not been revealed.
Henri ePuttonen +4 more
doaj +1 more source
Prevalence of Histidine Decarboxylase Genes of Gram-Positive Bacteria in Surströmming as Revealed by qPCR. [PDF]
Indian J Microbiol, 2021 Belleggia L +6 more
europepmc +1 more source
The effects of drugs on worm expulsion in the Nippostrongylus brasiliensis infected rat: a discussion of the interpretation of drug action [PDF]
, 2017 In rats treated with compound 48/80 or histamine, worm expulsion was inhibited. Treatment with a histidine decarboxylase inhibitor accelerated worm expulsion. Treatment with compound 48/80 elevates histamine and histidine decarboxylase levels and reduces
Keller, R., Ogilvie, Bridget M.
core
Journal of Pharmacological Sciences, 2016 Antihistamines inhibit histamine signaling by blocking histamine H1 receptor (H1R) or suppressing H1R signaling as inverse agonists. The H1R gene is upregulated in patients with pollinosis, and its expression level is correlated with the severity of ...
Hiroyuki Mizuguchi +7 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2010 Using extracellular single unit recordings, we have determined the characteristics of neurons in the ventral tuberomammillary nucleus (VTM) of wild-type (WT) and histidine decarboxylase knock-out (HDC-KO) mice during the sleep-waking cycle.
Kazuya Sakai +3 more
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