Results 81 to 90 of about 95,056 (227)
MOLECULAR MODELING AND NMR STUDY OF HISTDINIE AND ITS ANALOGUES AS , PYRIDOXAL 5 '-PHOSPHATE DEPENDENT HISTIDINE DECARBOXYLASE INHIBITORS [PDF]
Journal of Sciences, Islamic Republic of Iran, 1998 Molecular modeling analysis of charge density and heat of fornation by PM3 method as well as C, H NMR and 2D-NMR measurements of histidine (substrate) and some of its derivatives as histidine decarboxylase inhibitors were performed.
doaj
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
Adaptive increase in mammalian histidine decarboxylase activity in response to nonspecific stress
, 1959 Adaptive increase in histidine decarboxylase activity has been found to occur in all of the three species tested after a variety of stressful stimuli in rat skin following injection of polymyxin B, in mouse skin after burns, in lungs of mice injected ...
Oswald H. Ganley, Richard W. Schayer
core +1 more source
Chemical Engineering Transactions, 2019 Total DNA extracted from bacteriocinogenic and potential probiotic lactic acid bacteria (LAB) (Lactobacillus curvatus ET06, ET30 and ET31, Lactobacillus fermentum ET35, Lactobacillus delbrueckii ET32, Pediococcus acidilactici ET34 and Enterococcus ...
Svetoslav Todorov +2 more
doaj +1 more source
Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance
The FEBS Journal, EarlyView.Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley +1 more source
LPS-caused secretion of corticosterone is mediated by histamine through histidine decarboxylase
, 1986 Escherichia coli lipopolysaccharide (LPS) induced strong time- and dose-dependent secretion of corticosterone (CS) in C3H/HeN mice. In contrast, C3H/HeJ mice were very insensitive to LPS; 100,000 times more LPS was required with C3H/HeJ mice for ...
S. Suzuki, K. Nakano
core +1 more source
Squalen, 2020 Histamine-producing bacteria to predict histamine level production can be identified by a molecular approach. The purpose of this study was to identify the types of histamine-producing bacteria on tuna, little tuna, and skipjack (TTC) meat, to analyze ...
Mala Nurilmala +5 more
doaj +1 more source
The FEBS Journal, EarlyView.Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara +5 more
wiley +1 more source
Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm
MicrobiologyOpen, Volume 15, Issue 5, October 2026.Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Katie C. Sprinkel +2 more
wiley +1 more source
Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder
International Journal of Eating Disorders, Volume 59, Issue 9, Page 2059-2075, September 2026.ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang +4 more
wiley +1 more source