Results 131 to 140 of about 26,891 (179)

Bacterial histidine decarboxylase in rat stomach

European Journal of Pharmacology, 1970
Abstract Two histadine decarboxylase activities have been found in rat stomach. One, in the supernatant fraction of stomach homogenate, had optimum activity at pH 7 and appeared similar to the specific mammalian L-histidine decarboxylase (EC 4.1.1.22) descrideb by other workers.
M A Beaven, Z Horakova, W B Severs
exaly   +3 more sources

Inhibition of histidine decarboxylases

Life Sciences, 1963
Abstract Histidine decarboxylases of mammalian origin are of two main types. One of these acts not only on histidine but also on other aromatic amino acids, notably L-3,4-dihydroxyphenylalanine (DOPA) and L-5-hydroxytryptophan. A typical example of this non-specific enzyme, for which the term aromatic L-amino acid decarboxylase has been suggested1 ...
J D, REID, D M, SHEPHERD
openaire   +2 more sources

Histidine Decarboxylase and Growth

Nature, 1961
KAHLSON1,2 has presented evidence of a relationship between activity of histidine decarboxylase and growth or wound-healing in rat tissues. In particular he has shown that the developing liver of the fœtal rat has much higher histidine decarboxylase activity than the normal liver of adults.
D, MACKAY, J D, REID, D M, SHEPHERD
openaire   +2 more sources

Gastric histidine decarboxylase

Analytical Biochemistry, 1968
Abstract A simple method is described for determining histidine decarboxylase activity. It depends on the measurement of 14 CO 2 liberated from tracer carboxyl- 14 C- l -histidine. The method is sensitive enough to permit measurements in small samples of gastric mucosa of individual rats. It is specific in that dopa decarboxylase does not interfere.
P E, Powell, M A, Kumar
openaire   +2 more sources

Inhibition of histidine decarboxylase. Derivatives of histidine

Journal of Medicinal Chemistry, 1977
Twenty-eight derivatives of histidine were tested as inhibitors of histidine decarboxylase from rat stomach. Potent inhibition was observed with the methyl ester of L-histidine (1) which had a Ki = 1.8 X 10(-6) M. Substitution on 1 at various positions resulted in a decrease or complete loss of inhibition.
J L, Kelley, C A, Miller, H L, White
openaire   +2 more sources

A microassay for mammalian histidine decarboxylase

Analytical Biochemistry, 1975
Abstract This report describes a microassay procedure for mammalian histidine decarboxylase (HDC) based on the measurement of [ 14 C]O 2 formed from l -[1- 14 C]histidine. This assay is particularly useful for quick measurement of HDC activity both in microgram quantities of cell or tissue extract and in tissues that contain significant levels of ...
D G, Ritchie, D A, Levy
openaire   +2 more sources

Primary structure of histidine decarboxylase

Bulletin of Experimental Biology and Medicine, 1989
The results of investigation of the primary structure of the Histidine Decarboxylase Micrococcus sp. n. are reported. A comparison of the primary structure of the Histidine Decarboxylase Micrococcus sp. n. with that of the Lactobacillus 30a enzyme suggests the alignment with a 52% identity. It is therefore highly probable that two proteins have evolved
V N, Prozorovskiĭ, A E, Alekseeva, O G, Grebenshchikova   +2 more
openaire   +2 more sources

A rapid histidine decarboxylase assay

Analytical Biochemistry, 1978
Abstract Histidine decarboxylase (EC 4.1.1.22) catalyzes the conversion of histidine to histamine. Because current assays for enzyme activity are time consuming and require additional enzymes or large amounts of tissue, a rapid radioisotopic assay was devised.
R, Roskoski, L M, Roskoski
openaire   +2 more sources

Histidine Decarboxylase and Dopa Decarboxylase

1970
The concept of neural transmission is intimately connected with that of the functional significance of the biogenic amines. Although so far relatively few amines have been recognized as transmitter compounds, it is frequently assumed that all amines in the central nervous systems (CNS) have some function related to the control or facilitation of ...
Dorothea Aures, Rolf Håkanson, William G. Clark   +2 more
openaire   +1 more source

Histidine decarboxylase and DOPA decarboxylase in the stomach of the developing rat

Experientia, 1968
Im Magen der fotalen Ratte erreicht die Dopadecarboxylase-Aktivitat 19 Tage nach der Paarung Werte, die den Aktivitatswerten des erwachsenen Tieres entsprechen. Die Aktivitat bleibt auch wahrend der weiteren Entwicklung hoch. Die Histidindecarboxylase des fotalen Rattenmagens ist wahrend der embryonalen Entwicklung hoch, aber die Aktivitatswerte fallen
D, Aures, R, Håkanson
openaire   +2 more sources