Improved Acid Stress Survival of Lactococcus lactis Expressing the Histidine Decarboxylation Pathway of Streptococcus thermophilus CHCC1524 [PDF]
Background: Degradative amino acid decarboxylation pathways in bacteria have diverse physiological functions. Results: A histidine decarboxylation pathway introduced in L.
Lolkema, Juke S.+2 more
core +2 more sources
Background: Histidine is an important amino acid with important properties that enable it to play a vital part in many activities in the human body, such as proton buffering, metal ion chelation, scavenging of reactive oxygen and nitrogen species ...
Sarab M Alazawi +3 more
doaj +2 more sources
Pyridoxal phosphate (PLP)-dependent enzymes are one of the most important enzymes involved in plant N metabolism. Here, we explored the evolution of group II PLP-dependent decarboxylases (PLP_deC), including aromatic L-amino acid decarboxylase, glutamate
Rahul Kumar+5 more
doaj +1 more source
Histidine decarboxylase in the stomach of the rat
Abstract Two enzymes capable of decarboxylating l-histidine in vitro have been identified in rat and mouse stomach; one, located in the fundic portion, shows maximal activity at a pH value of 5.6, whilst the other, in the pyloric portion, requires a pH of 7.6 for optimal activity.
G. B. West, Abdalla G. Radwan
openaire +3 more sources
Effect of eliminating hdcA gene of Staphylococcus epidermidis TYH1 on Histamine production
Background and Objectives: The possible adverse effect of histamine on human health has made it a detrimental aspect to the quality and safety of many fermented food products especially fish sauce.
Safoora Pashangeh+5 more
doaj +1 more source
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons [PDF]
Zolpidem, a GABAA receptor-positive modulator, is the gold-standard drug for treating insomnia. Zolpidem prolongs IPSCs to decrease sleep latency and increase sleep time, effects that depend on α2 and/or α3 subunit-containing receptors.
Brickley, SG+9 more
core +4 more sources
Localization and function of neurosecretory protein GM, a novel small secretory protein, in the chicken hypothalamus. [PDF]
Recently, we discovered a novel cDNA encoding the precursor of a small secretory protein, neurosecretory protein GL (NPGL), in the hypothalamic infundibulum of chickens. NPGL plays an important role in the regulation of growth and feeding.
Bentley, George+9 more
core +3 more sources
Investigation of diverse bacteria encoding histidine decarboxylase gene in Sichuan-style sausages by culture-dependent techniques, polymerase chain reaction-denaturing gradient gel electrophoresis, and high-throughput sequencing [PDF]
The diverse bacteria encoding histidine decarboxylase gene during the fermentation of Sichuan-style sausages were investigated by culture-dependent techniques, polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE), and high ...
Chen, Shujuan+13 more
core +1 more source
Theory of cooperation in a micro-organismal snow-drift game [PDF]
We present a mean field model for the phase diagram of a community of micro-organisms, interacting through their metabolism so that they are, in effect, engaging in a cooperative social game. We show that as a function of the concentration of the nutrients glucose and histidine, the community undergoes a phase transition separating a state in which one
arxiv +1 more source
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu+4 more
wiley +1 more source