Results 61 to 70 of about 26,592 (294)

Substrates modulate charge-reorganization allosteric effects in protein-protein association [PDF]

open access: yesarXiv, 2021
Protein function may be modulated by an event occurring far away from the functional site, a phenomenon termed allostery. While classically allostery involves conformational changes, we recently observed that charge redistribution within an antibody can also lead to an allosteric effect, modulating the kinetics of binding to target antigen.
arxiv  

Sequence analysis of the cupin gene family in Synechocystis PCC6803 [PDF]

open access: yes, 1998
The recently described cupin superfamily of proteins includes the germin and germinlike proteins, of which the cereal oxalate oxidase is the best characterized.
DUNWELL J.M.   +5 more
core   +1 more source

Oxidative Stress in Antigen Processing and Presentation

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang   +9 more
wiley   +1 more source

Computational Studies about the Interactions of Nanomaterials with Proteins and their Impacts [PDF]

open access: yes, 2015
Intensive concerns about the biosafety of nanomaterials demand the systematic study of the mechanisms about their biological effects. Many biological effects can be attributed to the interaction of nanomaterials with protein and their impacts on protein function.
arxiv   +1 more source

Inferring interaction partners from protein sequences [PDF]

open access: yesProc. Natl. Acad. Sci. U.S.A., 113(43): 12180-12185 (2016), 2016
Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in coevolution between the interaction partners, causing their sequences to be correlated.
arxiv   +1 more source

Decarboxylases of histidine and ornithine in chick embryo [PDF]

open access: yesBritish Journal of Pharmacology, 1971
Summary The activities of histidine and ornithine decarboxylases as well as the histamine content of the developing chick embryo were studied. Histidine decarboxylase (l‐histidine carboxy‐lyase; E.C. 4.1.1.22) activity was fairly low with a tendency to increase at later stages of development.
Elsa Rosengren, Yao C. G. Dzodzœ
openaire   +3 more sources

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

open access: yesNeuropathology, Volume 45, Issue 3, Page 177-201, June 2025.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata   +6 more
wiley   +1 more source

Influences of Beta-Alanine and l-Histidine Supplementation on Growth Performance, Meat Quality, Carnosine Content, and mRNA Expression of Carnosine-Related Enzymes in Broilers

open access: yesAnimals, 2021
The current study investigated the effect of dietary l-histidine and beta-alanine supplementation on growth performance, meat quality, carnosine content, and gene expression of carnosine-related enzymes in broilers.
Bo Qi   +7 more
doaj   +1 more source

Dynamical coupling between protein conformational fluctuation and hydration water: Heterogeneous dynamics of biological water [PDF]

open access: yesChemical Physics Letters. Volume 683, Pages 29-37 (2017), 2017
We investigate dynamical coupling between water and amino acid side-chain residues in solvation dynamics by selecting residues often used as natural probes, namely tryptophan, tyrosine and histidine, located at different positions on protein surface and having various degrees of solvent exposure.
arxiv   +1 more source

Xenopus NM23-X4 regulates retinal gliogenesis through interaction with p27Xic1 [PDF]

open access: yes, 2009
Background. In Xenopus retinogenesis, p27Xic1, a Xenopus cyclin dependent kinase inhibitor, functions as a cell fate determinant in both gliogenesis and neurogenesis in a context dependent manner.
Aikaterini Bilitou   +6 more
core   +3 more sources

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