Results 51 to 60 of about 1,192,564 (261)
Frontiers in Pharmacology, 2015 Reversible phosphorylation of amino acid side chains in proteins is a frequently used mechanism in cellular signal transduction and alterations of such phosphorylation patterns are very common in cardiovascular diseases.
Thomas Wieland, Paul V. Attwood
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Characterization of CHARK, an unusual cytokinin receptor of rice
Scientific Reports, 2021 The signal transduction of the plant hormone cytokinin is mediated by a His-to-Asp phosphorelay. The canonical cytokinin receptor consists of an extra cytoplasmic hormone binding domain named cyclase/histidine kinase associated sensory extracellular ...
Mhyeddeen Halawa +3 more
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Probing the nucleotide-binding activity of a redox sensor: two-component regulatory control in chloroplasts [PDF]
, 2016 Two-component signal transduction systems mediate adaptation to environmental changes in bacteria, plants, fungi, and protists. Each two-component system consists of a sensor histidine kinase and a response regu- lator. Chloroplast sensor kinase (CSK) is
Allen, JF +3 more
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Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition.
Bioorganic & Medicinal Chemistry, 2018 Histidine kinases of bacterial two-component systems are promising antibacterial targets. Despite their varied, numerous roles, enzymes in the histidine kinase superfamily share a catalytic core that may be exploited to inhibit multiple histidine kinases
Kaelyn E. Wilke +2 more
semanticscholar +1 more source
A Unique Sensor Histidine Kinase [PDF]
Journal of Bacteriology, 2009 Sporulation initiation in Bacillus species is controlled by an extended version of two-component signal transduction systems, termed phosphorelay ([4][1]). The cascade of His→Asp→His→Asp phosphotransfer is typically initiated by the ATP-dependent autophosphorylation of the histidine ...
openaire +2 more sources
mBioThe two-component system (TCS) enables bacteria to sense and respond to environmental changes through histidine kinase-mediated signaling cascades. Although the core components of TCSs have been extensively studied, the molecular basis of accessory ...
Piqian Gong +7 more
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Biochemistry and Biophysics Reports, 2018 The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism.
Jimena Rinaldi +6 more
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Preliminary Study of Resistance Mechanism of Botrytis cinerea to SYAUP-CN-26
Molecules, 2022 SYAUP-CN-26 (1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide) is a novel sulfonamide compound with excellent activity against Botrytis cinerea.
Kai Wang +6 more
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Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences [PDF]
, 2007 A new algorithm is presented for vocabulary analysis (word detection) in texts of human origin. It performs at 60%–70% overall accuracy and greater than 80% accuracy for longer words, and approximately 85% sensitivity on Alice in Wonderland, a ...
Gatherer, D.
core +4 more sources
A Transmembrane Histidine Kinase Functions as a pH Sensor
Biomolecules, 2020 The two-component system DesK-DesR regulates the synthesis of unsaturated fatty acids in the soil bacteria Bacillus subtilis. This system is activated at low temperature and maintains membrane lipid fluidity upon temperature variations.
Ana Bortolotti +8 more
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