Results 21 to 30 of about 38,208 (195)
Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study
Orphanet Journal of Rare Diseases, 2020 Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet +25 more
doaj +1 more source
Journal of Indian Society of Periodontology, 2011 Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
Sushma Galgali +3 more
openaire +3 more sources
Langerhans cell histiocytosis on the penis: a case report
BMC Urology, 2006 Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao +5 more
doaj +1 more source
Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient [PDF]
Malaysian Orthopaedic Journal, 2011 Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations.
Mohd Ariff S +3 more
doaj +1 more source
Langerhans' Cell Histiocytosis
Dermatology Online Journal, 2002 Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Mortazavi, Hessein +3 more
openaire +4 more sources
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis
Cell Communication and Signaling, 2022 Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj +1 more source
Survey of Ophthalmology, 2008 Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia characterized by accumulation of clonal CD1a-positive immature dendritic cells (LCH cells) accompanied by infiltration of various inflammatory cells such as eosinophils, lymphocytes, macrophages, and osteoclast-like multinuclear giant cells.
Department of Ophthalmology and Pathology, University of South Florida, College of Medicine, and Section of Ophthalmology James A. Haley Veterans Hospital, Tampa, Florida, USA ( host institution ) +2 more
openaire +6 more sources
Langerhans Cell Histiocytosis [PDF]
Cancer Control, 2014 Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Scott Kelly, Michael T. Yen
openaire +5 more sources
Haematologica, 2008 Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku +13 more
doaj +1 more source
Journal of Contemporary Medicine, 2022 Scabies is an infestation caused by the Sarcoptes scabiei burrowing into the epidermis. Histopathologically scabies infestation may reveal Langerhans cell hyperplasia which might cause misdiagnosis of Langerhans cell histiocytosis in some cases.
Ayşe Esra Koku Aksu +5 more
doaj +1 more source