Results 21 to 30 of about 17,531 (194)

Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient [PDF]

Malaysian Orthopaedic Journal, 2011
Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations.
Mohd Ariff S, Joehaimey J, Ahmad Sabri O, Zulmi W   +3 more
doaj   +1 more source

Langerhans' Cell Histiocytosis

Dermatology Online Journal, 2002
Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Mortazavi, Hessein, Ehsani, Amirhoushang, Namazi, Mohammad Reza, Hosseini, Mahbobeh   +3 more
openaire   +4 more sources

Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study

Orphanet Journal of Rare Diseases, 2020
Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet, Mohamed-Aziz Barkaoui, Jean Miron, Claire Galambrun, Nathalie Aladjidi, Pascal Chastagner, Kamila Kebaili, Corinne Armari-Alla, Anne Lambilliotte, Julien Lejeune, Despina Moshous, Valeria Della Valle, Chiara Sileo, Hubert Ducou Le Pointe, Jean-François Chateil, Sylvain Renolleau, Jean-Eudes Piloquet, Aurelie Portefaix, Ralph Epaud, Raphaël Chiron, Emmanuelle Bugnet, Gwenaël Lorillon, Abdelatif Tazi, Jean-François Emile, Jean Donadieu, Sébastien Héritier   +25 more
doaj   +1 more source

Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Cell Communication and Signaling, 2022
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj   +1 more source

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report [PDF]

, 2012
INTRODUCTION: Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults.
Chicoine, Michael R, Ferraro, Daniel J, Funk, Ryan K, Hurth, Kyle M, Jaboin, Jerry J, Mansur, David B, Perrin, Richard J, Simpson, Joseph R, Stephens, John J   +8 more
core   +2 more sources

Infantile and Adult Scabies mimicking Langerhans Cell Histiocytosis Clinically and Histopathologically

Journal of Contemporary Medicine, 2022
Scabies is an infestation caused by the Sarcoptes scabiei burrowing into the epidermis. Histopathologically scabies infestation may reveal Langerhans cell hyperplasia which might cause misdiagnosis of Langerhans cell histiocytosis in some cases.
Ayşe Esra Koku Aksu, Cem Leblebici, Duygu Erdil, Ecem Ergün, Dilara İlhan, Vildan Manav   +5 more
doaj   +1 more source

A rare case of oral multisystem Langerhans cell histiocytosis [PDF]

, 2017
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of Langerhans dendritic cells. LCH is a solitary or multifocal disease that primarily involves bone tissue and often affects children and young men. A 29 years-old
Facciolo, Maria Teresa, Gaglioti, Domenico, Gallenzi, Patrizia, Patini, Romeo, Riva, Francesco   +4 more
core   +1 more source

Neurodegenerative central nervous system disease as late sequelae of Langerhans cell histiocytosis. Report from the Japan LCH Study Group

Haematologica, 2008
Clinical features, brain magnetic resonance imaging findings and EDSS scores of 11 patients with neurodegenerative central nervous system Langerhans cell histiocytosis were analyzed in Japan.
Shinsaku Imashuku, Yoko Shioda, Ryoji Kobayashi, Gaku Hosoi, Hisanori Fujino, Shiro Seto, Hisashi Wakita, Akira Oka, Nagisa Okazaki, Naoto Fujita, Toshinori Minato, Kenichi Koike, Yukiko Tsunematsu, Akira Morimoto   +13 more
doaj   +1 more source

Pulmonary Langerhans cell histiocytosis causing spontaneous bilateral pneumothorax in a child

The Egyptian Journal of Internal Medicine, 2015
Bilateral pneumothorax is very rare in childhood. Moreover, if it is due to pulmonary involvement of Langerhans cell histiocytosis, it is even rarer in childhood.
Anupam Patra, Sujit K Bhattacharyay, Arnab Maji, Abhijit Mandal   +3 more
doaj   +1 more source

Swelling of bilateral parotid glands: An unusual symptom of multisystem Langerhans cell histiocytosis

SAGE Open Medical Case Reports, 2014
Objective: Langerhans cell histiocytosis is an unusual disorder of unknown etiology with heterogeneous clinical behaviors and variable outcomes. It can involve one or more organs or systems, but to our best knowledge, parotid glands involvement in ...
Xiaojun Yuan, Mengjie Tang, Qi Sheng, Xiaodong Zhu, Qin Zhang   +4 more
doaj   +1 more source