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Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
Sushma Galgali+3 more
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Pulmonary Langerhans cell histiocytosis causing spontaneous bilateral pneumothorax in a child
Bilateral pneumothorax is very rare in childhood. Moreover, if it is due to pulmonary involvement of Langerhans cell histiocytosis, it is even rarer in childhood.
Anupam Patra+3 more
doaj +1 more source
Objective: Langerhans cell histiocytosis is an unusual disorder of unknown etiology with heterogeneous clinical behaviors and variable outcomes. It can involve one or more organs or systems, but to our best knowledge, parotid glands involvement in ...
Xiaojun Yuan+4 more
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Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis.
Alejandro Peralta Soler+2 more
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Three cases of congenital self‐healing Langerhans cell histiocytosis with BRAF‐V600E mutation
Congenital self‐healing Langerhans cell histiocytosis (CSHLCH) is a rare variant of Langerhans cell histiocytosis characterised by the presence of skin lesions in the neonate and spontaneous self‐healing after a variable period of time.
Mar Ramírez‐Lluch+7 more
doaj +1 more source
Deep Multi-Scale U-Net Architecture and Label-Noise Robust Training Strategies for Histopathological Image Segmentation [PDF]
Although the U-Net architecture has been extensively used for segmentation of medical images, we address two of its shortcomings in this work. Firstly, the accuracy of vanilla U-Net degrades when the target regions for segmentation exhibit significant variations in shape and size.
arxiv
Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report [PDF]
INTRODUCTION: Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults.
Chicoine, Michael R+8 more
core +2 more sources
Expansion of Regulatory T Cells in Patients with Langerhans Cell Histiocytosis [PDF]
Frederic Geissmann and colleagues find that Langerhans cell accumulation in Langerhans cell histiocytosis results from survival rather than uncontrolled proliferation, and is associated with the expansion of regulatory T ...
Alain Fischer+70 more
core +5 more sources
Isolated Langerhans Histiocytosis in Thyroid: Thyroidectomy or Chemotherapy? [PDF]
Langerhans cell histiocytosis (LCH) is a rare disorder of mononuclear phagocytic system whose clinical presentation varies from the localised involvement of a single bone to a widely disseminated disease.
Anoop Attakkil+4 more
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A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult
Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
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