Results 51 to 60 of about 9,611 (207)

Eosinophilic Granuloma: A Rare and Often Benign Condition Presenting as a Lump on the Head, which was Easily Treated

European Journal of Case Reports in Internal Medicine, 2021
Eosinophilic granuloma is a localized, non-invasive form of Langerhans cell histiocytosis. It usually develops in the long bones and is more frequent in children under the age of 10 years. It is very rare in adults.
Tatiana Pires, Catarina Duarte Santos, Miguel Gonzalez Santos, Luís Luz, Ana Ferrão, Maria J. Banza   +5 more
doaj   +1 more source

Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]

, 2019
Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta, Doueiri, Mohemed-Salim, Heiland, Max, Lissat, Andrej, Neckel, Norbert, Raguse, Jan-Dirk, Spors, Birgit, Stackelberg, Arendt von, Thieme, Nadine   +8 more
core   +1 more source

An unusual case of intracerebral Non-Langerhans cell histiocytosis with review of the literature [PDF]

Diagnostic Pathology, 2007
Conclusion This case shows the unusual manifestation of a primary intracerebral Non-Langerhans cell histiocytosis, which begins as a solid mass around the sellar region and shows a remarkable extension as a flat lining of inner and outer liquor spaces.
Mueller, K., Trippel, M., Berlis, Ansgar, Janzarik, W., Volk, B.   +4 more
openaire   +2 more sources

Longitudinal Patterns of Fatigue in Long‐Term Survivors of Childhood and Adolescent Cancers: A Report From the Swiss Childhood Cancer Survivor Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fatigue negatively affects quality of life. We aimed to compare the prevalence of fatigue in survivors of childhood cancer with the Swiss general population, describe longitudinal patterns of fatigue, and identify characteristics associated with persistent fatigue in survivors.
Salome Christen, Luzius Mader, André O. von Bueren, Eva Maria Tinner, Grit Sommer, Christina Schindera, Claudia E. Kuehni, Katharina Roser, Gisela Michel   +8 more
wiley   +1 more source

Unravelling a hidden case of Erdheim-Chester disease in persistent pericardial effusion

Romanian Journal of Cardiology
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell, non-familial multisystemic histiocytosis, with widespread manifestations and of highly variable severity.
Alexandru Trenchea, Alexandru Cramba, Valentin Simon, Phillipe Couppie, Carina Ureche, Cristian Statescu, Radu-Andy Sascau   +6 more
doaj   +1 more source

Solving a Mystery . . . 8 Years Later

Journal of Investigative Medicine High Impact Case Reports, 2018
Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis with multisystem involvement and insidious symptoms. In this article, we describe an interesting case of Erdheim-Chester disease that was eventually diagnosed 8 years after symptoms ...
Hayan Jouni MD, Ronald S. Kuzo MD, Nandan S. Anavekar MBBCh   +2 more
doaj   +1 more source

Multisystem Langerhans' cell histiocytosis (Hand-Schüller-Christian disease) in an adult: a case report and review of the literature [PDF]

, 2018
Langerhans' cell histiocytosis (LCH) is a rare and enigmatic clonal disorder that affects mainly children. It is characterized by single or multiple granulomatous mass lesions composed of cells with the Langerhans' cell phenotype.
Jaques, B., Lombardi, T., Monnier, P., Scolozzi, P.   +3 more
core  

Erdheim Chester disease – 25 year history with early CNS involvement [PDF]

, 2016
We report a case of Erdheim-Chester disease (ECD) with a 25-year history following initial presentation with diabetes insipidus and brainstem involvement.
Cohen, N, Hall, C A, McCoubrie, Paul, Renowden, S, Rice, Claire, Scolding, Neil   +5 more
core   +1 more source

MEK Inhibition with Trametinib in Patients with Non-Langerhans Cell Histiocytosis

Blood, 2019
Background: Activation of the MAPK pathway through BRAF mutations or other molecular alterations is a hallmark of the non-Lagerhans cell histiocytosis (non-LCH) such Erdheim-Chester disease (ECD) or Rosai-Dorfman disease (RDD). Conventional clinical molecular testing of tumor tissue fails to identify targetable molecular alteration in about one third ...
Filip Janku, Harsh Patel, Vaijayanthi Kandadai Raghavan, Aaron Goodman, Tamara G. Barnes, Razelle Kurzrock   +5 more
openaire   +1 more source

Multicentric reticulohistiocytosis: a case report

BMC Research Notes, 2018
Background Multicentric reticulohistiocytosis is a rare form of non-langerhans cell histiocytosis presenting with skin changes and erosive arthritis. Infiltration of histiocytes and multinucleated giant cells are typical histological findings and confirm
Azadèh Farokhi, Richard M. van Vugt, Rick Hoekzema, Michael T. Nurmohamed   +3 more
doaj   +1 more source