Results 51 to 60 of about 14,204,460 (231)

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Indeterminate Cell Histiocytosis: Report of a Case

Acta Medica Iranica, 2014
Indeterminate cell histiocytosis is a very rare disorder of histiocytes proliferation. It has both Langerhans and non-Langerhans cell histiocytosis immunophenotypic features.
Alireza Ghanadan, Kambiz Kamyab, Mazaher Ramezani, Azadeh Goodarzi, Maryam Daneshpajouh, Kamran Balighi, Mahsa Ansari, Seyyed Farzad Mirfallah Nassiri, Soroush Daklan   +8 more
doaj  

CT‐Based Biomarkers for Predicting Progressive Phenotypes in Interstitial Lung Diseases: A Retrospective Cohort Study

Respirology, EarlyView.
This study demonstrates that the Single Time Point Prediction score, a novel machine learning–based imaging biomarker, along with established quantitative CT measures, is significantly associated with disease progression in non‐IPF ILD. This imaging metric may enable earlier identification of high‐risk patients and support personalised treatment ...
Ju Hyun Oh, Jin Woo Song, Jonathan Goldin, S. Samuel Weigt, Augustine Chung, Jared D. Wilkinson, Fereidoun Abtin, Lila Pourzand, Bianca Villegas, Jihey Lee, Kyungjong Lee, Grace Hyun J. Kim   +11 more
wiley   +1 more source

Extraosseous langerhans cell histiocytosis in children

, 2008
Langerhans cell histiocytosis, a rare disease that occurs mainly in children, may produce a broad range of manifestations, from a single osseous lesion to multiple lesions involving more than one organ or system.
Letovanec, I., Geoffray, A., Letovanec, Igor, Waibel, Peter, Georg Eich, Peter Waibel, Schmidt, S., Gudinchet, Francois, Hanquinet, Sylviane, Eich, Georg, Anne Geoffray, Wolf, R., Rainer Wolf, Sabine Schmidt, Geoffray, Anne, Hanquinet, S., Schmidt, Sabine, Alamo-Maestre, L., Francois Gudinchet, Alamo-Maestre, Leonore, Eich, G., Gudinchet, F., Igor Letovanec, Leonore Alamo-Maestre, Waibel, P., Wolf, Rainer, Sylviane Hanquinet   +26 more
core   +1 more source

Successful treatment of non-Langerhans cell histiocytosis with the MEK inhibitor trametinib: a multicenter analysis

Blood Advances, 2023
Abstract Erdheim-Chester disease (ECD) and Rosai-Dorfman disease (RDD) are rare non-Langerhans cell histiocytoses (non-LCHs), for which therapeutic options are limited. MAPK pathway activation through BRAFV600E mutation or other genomic alterations is a histiocytosis hallmark and correlates with a favorable response to BRAF inhibitors ...
Ashley Aaroe, Razelle Kurzrock, Gaurav Goyal, Aaron M. Goodman, Harsh Patel, Gordon Ruan, Gary Ulaner, Jason Young, Ziyi Li, Derek Dustin, Ronald S. Go, Eli L. Diamond, Filip Janku   +12 more
openaire   +2 more sources

Solitary Indeterminate Cell Histiocytosis Presenting as a Reddish Nodule on the Abdomen of a 4‐Year‐Old Boy: Clinicopathologic Correlation and Electron Microscopy Findings

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Indeterminate cell histiocytosis (ICH) is a clonal proliferative disorder of mononuclear phagocyte cells that shows features of both dendritic and histiocytic cells. Only around 100 cases of ICH were reported, and among them, only 24% of reported cases involve pediatric patients, with a mean age at diagnosis of 50 years.
Seung‐Soo Lee, Seok‐Jong Lee, Weon Ju Lee, Dae‐Lyong Ha   +3 more
wiley   +1 more source

The clinicopathological characteristics and differential diagnosis of histiocytosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
The histiocytosis is divided into Langerhans' cell histiocytosis (histiocytosis X) and non-Langerhans' cell histiocytosis (NLCH). The former mainly occurs in lymphatic hematopoietic tissue and often involves central nervous system (CNS).
Shi-zhu YU
doaj  

A rare cutaneous lesion in the neonatal period: The non-Langerhans cell histiocytosis

Marmara Medical Journal, 2020
The non-Langerhans cell histiocytosis (non-LCH) is a group of diseases characterized by cutaneous involvement in the neonatal period. The non-LCH affects less than 1 in 200,000 children born each year. A definitive diagnosis is important for the treatment of the disease.
Adnan BARUTCU, Ferda OZLU, Hacer YAPICIOGLU YILDIZDAS, Mehmet SATAR   +3 more
openaire   +3 more sources

An unusual case of intracerebral Non-Langerhans cell histiocytosis with review of the literature [PDF]

Diagnostic Pathology, 2007
Conclusion This case shows the unusual manifestation of a primary intracerebral Non-Langerhans cell histiocytosis, which begins as a solid mass around the sellar region and shows a remarkable extension as a flat lining of inner and outer liquor spaces.
Mueller, K., Trippel, M., Berlis, Ansgar, Janzarik, W., Volk, B.   +4 more
openaire   +2 more sources