Results 101 to 110 of about 249,831 (220)

Effect of Infant and Maternal Secretor Status on Rotavirus Vaccine Take—An Overview

Viruses, 2021
Histo-blood group antigens, which are present on gut epithelial surfaces, function as receptors or attachment factors and mediate susceptibility to rotavirus infection.
Sumit Sharma, Johan Nordgren
doaj   +1 more source

Identifying the genetic basis of antigenic change in influenza A(H1N1) [PDF]

PLoS Pathogens (2016) 12(4): e1005526, 2014
Determining phenotype from genetic data is a fundamental challenge. Influenza A viruses undergo rapid antigenic drift and identification of emerging antigenic variants is critical to the vaccine selection process. Using former seasonal influenza A(H1N1) viruses, hemagglutinin sequence and corresponding antigenic data were analyzed in combination with 3-
arxiv   +1 more source

Rotavirus infection and histo-blood group antigens in the children hospitalized with diarrhoea in China [PDF]

Clinical Microbiology and Infection, 2016
To explore the association between rotavirus (RV) infection and histo-blood group antigens (HBGAs), a cross-sectional study was conducted in children hospitalized with diarrhoea in China from November 2014 to February 2015. In total, 424 sets of stool, saliva and buccal cell samples were collected.
Lili Pang, Lili Pang, Guang-Cheng Xie, Guang-Cheng Xie, Xiaoman Sun, Xiaoman Sun, Z. He, Xiaomei Yan, J. Li, J. Li, Zhao-jun Duan, Zhao-jun Duan, Na Liu, Na Liu, N. Guo, N. Guo, Dandi Li, Dandi Li, Qing Zhang, Qing Zhang, Miao Jin, Miao Jin   +21 more
openaire   +3 more sources

Elucidation of Dysregulated Pathways Associated With Hypoxia in Oestrogen Receptor‐Negative Breast Cancer

Cancer Medicine, Volume 13, Issue 23, December 2024.
ABSTRACT Purpose Carbonic anhydrase IX (CAIX) is a well‐established prognostic marker in breast cancer (BC). Nevertheless, this prognostic value is yet to be confirmed in BC subtypes. This study aims to investigate the prognostic effects of CAIX in oestrogen receptor (ER)‐negative (ER−) BCs and to establish pathways related to cytoplasmic CAIX ...
Suad A. K. Shamis, Jean Quinn, Sara Al‐Badran, Molly McKenzie, Phimmada Hatthakarnkul, Gerard Lynch, Guang‐Yu Lian, Warapan Numprasit, Laszlo Romics Jr., Ditte Andersen, Elizabeth Mallon, Donald C. McMillan, Joanne Edwards   +12 more
wiley   +1 more source

Astrocytic centrin‐2 expression in entorhinal cortex correlates with Alzheimer's disease severity

Glia, Volume 72, Issue 12, Page 2158-2177, December 2024.
Main Points Astroglial CETN2 immunoreactivity in entorhinal cortex correlates with AD‐related neuro‐decline and histological features. CETN2+ astrocytes co‐localize with reactive glia markers indicating a role in AD‐induced astrogliosis. Abstract Astrogliosis is a condition shared by acute and chronic neurological diseases and includes morphological ...
Elisa Degl'Innocenti, Tino Emanuele Poloni, Valentina Medici, Francesco Olimpico, Francesco Finamore, Xhulja Profka, Karouna Bascarane, Castrese Morrone, Aldo Pastore, Carole Escartin, Liam A. McDonnell, Maria Teresa Dell'Anno   +11 more
wiley   +1 more source

Diversity in Rotavirus–Host Glycan Interactions: A “Sweet” SpectrumSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Interaction with cellular glycans is a critical initial step in the pathogenesis of many infectious agents. Technological advances in glycobiology have expanded the repertoire of studies delineating host glycan–pathogen interactions. For rotavirus, the
Sasirekha Ramani, Liya Hu, B.V. Venkataram Prasad, Mary K. Estes   +3 more
doaj  

A stochastic microscopic model for the dynamics of antigenic variation [PDF]

arXiv, 2013
We present a novel model that describes the within-host evolutionary dynamics of parasites undergoing antigenic variation. The approach uses a multi-type branching process with two types of entities defined according to their relationship with the immune system: clans of resistant parasitic cells (i.e.
arxiv  

Myelinated Glial Cells: Their Proposed Role in Waste Clearance and Neurodegeneration in Arachnid and Human Brain

Journal of Comparative Neurology, Volume 532, Issue 11, November 2024.
We provide evidence that myelinated tanycytes likely remove cellular waste from the human hippocampus in an aquaporin‐4‐dependent manner for disposal from the brain. We propose that amyloid beta may play an important role in the differentiation and proliferation of these receptacles.
Ruth Fabian‐Fine, Adam L. Weaver, Abigail G. Roman, Melanie J. Winters, John C. DeWitt   +4 more
wiley   +1 more source

CD38, CD39, and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma

Cytometry Part B: Clinical Cytometry, Volume 106, Issue 6, Page 448-464, November 2024.
Abstract High‐grade B‐cell lymphomas (HGBCL) represent a heterogeneous group of very rare mature B‐cell lymphomas. The 4th revised edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues (WHO‐HAEM) previously defined two categories of HGBCL: the so‐called double‐hit (DHL) and triple‐hit (THL) lymphomas, which were related to ...
Pauline Marianini, Vanessa Lacheretz‐Szablewski, Marion Almeras, Jérôme Moreaux, Caroline Bret   +4 more
wiley   +1 more source

Glycan recognition in globally dominant human rotaviruses

Nature Communications, 2018
Human rotaviruses (RV) bind to histo-blood group antigens (HBGA) for attachment, but how different viral genotypes interact with HBGA isn’t known. Here, Hu et al. report crystal structures of a prevalent and a neonate-specific RV in complex with HBGA and
Liya Hu, Banumathi Sankaran, Daniel R. Laucirica, Ketki Patil, Wilhelm Salmen, Allan Chris M Ferreon, Phoebe S. Tsoi, Yi Lasanajak, David F. Smith, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes, Josephine C. Ferreon, B. V. Venkataram Prasad   +13 more
doaj   +1 more source