Results 41 to 50 of about 6,935 (192)
Affinities of human histo-blood group antigens for norovirus capsid protein complexes. [PDF]
Glycobiology, 2015 The binding profiles of many human noroviruses (huNoVs) for human histo-blood group antigens have been characterized. However, quantitative-binding data for these important virus–host interactions are lacking. Here, we report on the intrinsic (per binding site) affinities of HBGA oligosaccharides for the huNoV VA387 virus-like particles (VLPs) and the ...
Han L +6 more
europepmc +6 more sources
Human Group C Rotavirus VP8*s Recognize Type A Histo-Blood Group Antigens as Ligands. [PDF]
J Virol, 2018 Sun X +13 more
europepmc +3 more sources
Minimizing the Entropy Penalty for Ligand Binding: Lessons from the Molecular Recognition of the Histo Blood-Group Antigens by Human Galectin-3. [PDF]
Angew Chem Int Ed Engl, 2019 Gimeno A +11 more
europepmc +3 more sources
Frontiers in Cellular and Infection Microbiology, 2021 The glycosyltransferases encoded by genes from the human ABO, Lewis, and Secretor histo-blood group systems synthesize part of the carbohydrate antigens in hematopoietic and non-hematopoietic tissues.
Luiz Carlos De Mattos +5 more
doaj +1 more source
Lewis b antigen is a common ligand for genogroup I norovirus strains
FEBS Open Bio, 2022 Noroviruses are major causative agents of nonbacterial acute gastroenteritis in humans. Ten genogroups of noroviruses have been identified to date, among which genogroup I (GI) and genogroup II (GII) noroviruses are major pathogens for humans. GI and GII
Yuichi Someya
doaj +1 more source
Frontiers in Chemistry, 2021 The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the ...
Jon I. Quintana +11 more
doaj +1 more source
International Journal of Medical Microbiology, 2021 The glycosylation profile of the gastrointestinal tract is an important factor mediating host-microbe interactions. Variation in these glycan structures is often mediated by blood group-related glycosyltransferases, and can lead to wide-ranging ...
Alibek Galeev +5 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2021 Rotaviruses (RVs) are the leading cause of acute gastroenteritis in children, while histo-blood group antigens (HBGAs) are believed to be host attachment and susceptibility factors of RVs.
Jin-Xia Wang +14 more
doaj +1 more source
Histo-blood group antigens as mediators of infections [PDF]
Current Opinion in Structural Biology, 2017 The critical first step of a microbial infection is usually the attachment of pathogens to host cell glycans. Targets on host tissues are in particular the histo-blood group antigens (HBGAs), which are present in rich diversity in the mucus layer and on the underlying mucosa.
Heggelund, Julie E. +3 more
openaire +3 more sources
Frontiers in Microbiology, 2023 The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children.
Emmanuelle Godefroy +13 more
doaj +1 more source